Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C3H5NO3 |
| Molecular Weight | 103.0767 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)CNC=O
InChI
InChIKey=UGJBHEZMOKVTIM-UHFFFAOYSA-N
InChI=1S/C3H5NO3/c5-2-4-1-3(6)7/h2H,1H2,(H,4,5)(H,6,7)
| Molecular Formula | C3H5NO3 |
| Molecular Weight | 103.0767 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Recent N-atom containing compounds from indo-pacific invertebrates. | 2010-11-10 |
|
| Computational exploration of the mechanism of alcohol oxidation by dioxygen activated with biquinolyl-containing cu complexes. | 2010-04-05 |
|
| Sulfatase activities towards the regulation of cell metabolism and signaling in mammals. | 2010-03 |
|
| Efficient, chemoselective synthesis of immunomicelles using single-domain antibodies with a C-terminal thioester. | 2009-07-20 |
|
| Molecular basis of multiple sulfatase deficiency, mucolipidosis II/III and Niemann-Pick C1 disease - Lysosomal storage disorders caused by defects of non-lysosomal proteins. | 2009-04 |
|
| Characterization of the arylsulfatase I (ARSI) gene preferentially expressed in the human retinal pigment epithelium cell line ARPE-19. | 2009 |
|
| A new member of the alkaline phosphatase superfamily with a formylglycine nucleophile: structural and kinetic characterisation of a phosphonate monoester hydrolase/phosphodiesterase from Rhizobium leguminosarum. | 2008-12-05 |
|
| Sulfotransferases, sulfatases and formylglycine-generating enzymes: a sulfation fascination. | 2008-10 |
|
| New aldehyde tag sequences identified by screening formylglycine generating enzymes in vitro and in vivo. | 2008-09-17 |
|
| Function and structure of a prokaryotic formylglycine-generating enzyme. | 2008-07-18 |
|
| In vitro characterization of AtsB, a radical SAM formylglycine-generating enzyme that contains three [4Fe-4S] clusters. | 2008-07-15 |
|
| The non-catalytic N-terminal extension of formylglycine-generating enzyme is required for its biological activity and retention in the endoplasmic reticulum. | 2008-04-25 |
|
| ERp44 mediates a thiol-independent retention of formylglycine-generating enzyme in the endoplasmic reticulum. | 2008-03-07 |
|
| Paralog of the formylglycine-generating enzyme--retention in the endoplasmic reticulum by canonical and noncanonical signals. | 2008-03 |
|
| Molecular analysis of SUMF1 mutations: stability and residual activity of mutant formylglycine-generating enzyme determine disease severity in multiple sulfatase deficiency. | 2008-01 |
|
| Generation of quinoneimine intermediates in the bioactivation of 3-(N-phenylamino)alanine (PAA) by human liver microsomes: a potential link between eosinophilia-myalgia syndrome and toxic oil syndrome. | 2007-10 |
|
| Formamide as the main building block in the origin of nucleic acids. | 2007-08-16 |
|
| Human sulfatases: a structural perspective to catalysis. | 2007-08 |
|
| Probing the oxygen-binding site of the human formylglycine-generating enzyme using halide ions. | 2007-05 |
|
| SUMF1 enhances sulfatase activities in vivo in five sulfatase deficiencies. | 2007-04-15 |
|
| Ethanol decreases rat hepatic arylsulfatase A activity levels. | 2006-11 |
|
| Electron transfer in amino acid.nucleic acid base complexes: EPR, ENDOR, and DFT study of X-irradiated N-formylglycine.cytosine complex crystals. | 2006-07-20 |
|
| Alkaline Phosphatases : Structure, substrate specificity and functional relatedness to other members of a large superfamily of enzymes. | 2006-06 |
|
| Diversity in domain architectures of Ser/Thr kinases and their homologues in prokaryotes. | 2005-09-19 |
|
| De novo calcium/sulfur SAD phasing of the human formylglycine-generating enzyme using in-house data. | 2005-08 |
|
| Sulphatase activities are regulated by the interaction of sulphatase-modifying factor 1 with SUMF2. | 2005-07 |
|
| Molecular basis for multiple sulfatase deficiency and mechanism for formylglycine generation of the human formylglycine-generating enzyme. | 2005-05-20 |
|
| Three-dimensional structures of sulfatases. | 2005 |
|
| Overexpression of inactive arylsulphatase mutants and in vitro activation by light-dependent oxidation with vanadate. | 2004-09-01 |
|
| Crystal structure of a covalent intermediate of endogenous human arylsulfatase A. | 2003-08-01 |
|
| Posttranslational modification of serine to formylglycine in bacterial sulfatases. Recognition of the modification motif by the iron-sulfur protein AtsB. | 2003-01-24 |
|
| Identification of formylglycine in sulfatases by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. | 2003-01 |
|
| Estrone 3-sulfate mimics, inhibitors of estrone sulfatase activity: homology model construction and docking studies. | 2002-12-17 |
|
| Optosensing properties of fac-Re(CO)(3)(dpknph)Cl (dpknph=di-2-pyridyl ketone p-nitrophenyl hydrazone) toward chemotactic N-formylamino acids. | 2002-04-08 |
|
| Characterization of posttranslational formylglycine formation by luminal components of the endoplasmic reticulum. | 2001-12-14 |
|
| Conserved core structure and active site residues in alkaline phosphatase superfamily enzymes. | 2001-12-01 |
|
| Heparan N-sulfatase: cysteine 70 plays a role in the enzyme catalysis and processing. | 2001-09-21 |
|
| 1.3 A structure of arylsulfatase from Pseudomonas aeruginosa establishes the catalytic mechanism of sulfate ester cleavage in the sulfatase family. | 2001-06 |
|
| Crystal structure of an enzyme-substrate complex provides insight into the interaction between human arylsulfatase A and its substrates during catalysis. | 2001-01-12 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:34:01 GMT 2025
by
admin
on
Mon Mar 31 18:34:01 GMT 2025
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| Record UNII |
11F24CG16M
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| Record Status |
Validated (UNII)
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| Record Version |
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