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Details

Stereochemistry ACHIRAL
Molecular Formula C2H3N3
Molecular Weight 69.0653
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1H-1,2,4-TRIAZOLE

SMILES

N1C=NC=N1

InChI

InChIKey=NSPMIYGKQJPBQR-UHFFFAOYSA-N
InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)

HIDE SMILES / InChI

Molecular Formula C2H3N3
Molecular Weight 69.0653
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Polynucleating open-chain systems with imidazole and proton-ionizable 1,2,4-triazole structural motifs.
2001 Apr 6
Expanded phthalocyanine analogues: synthesis and characterization of new triazole-derived annulenes containing six heterocyclic subunits.
2001 Jun 1
A new class of nonsteroidal aromatase inhibitors: design and synthesis of chromone and xanthone derivatives and inhibition of the P450 enzymes aromatase and 17 alpha-hydroxylase/C17,20-lyase.
2001 Mar 1
Synthesis and antitumor activity of some new phthalimide analogues.
2001 May
Determination of benzylpenicillin, oxacillin, cloxacillin, and dicloxacillin in cows' milk by ion-pair high-performance liquid chromatography after precolumn derivatization.
2001 Sep
Synthesis of 3-alkyl(aryl)-4-alkylidenamino-4,5-dihydro-1H-1,2,4-triazol-5-ones and 3-alkyl-4-alkylamino-4,5-dihydro-1H-1,2,4-triazol-5-ones as antitumor agents.
2002 Dec
Tin-free radical sequences under acidic conditions. Convergent access to azole-containing structures.
2002 Nov 28
Different oxidation states of copper(I, I/II, II) thiocyanate complexes containing 1,2,4-triazole as a bridging ligand: syntheses, crystal structures, and magnetic properties of 2-D polymer Cu I(admtrz)SCN, linear trinuclear [CuI2CuII(admtrz)6(SCN)2](ClO4)2, and triangular trinuclear [CuII3(admtrz)4(SCN)3(mu3-OH)(H2O)](ClO4)2.H2O (admtrz = 4-amino-3,5-dimethyl-1,2,4-triazole).
2003 Jan 13
Synthesis of some functionalized arylaminomethyl-1 ,2,4-triazoles, 1,3,4-oxa- and thiadiazoles.
2003 Nov
Synthesis and antimycobacterial activity of 1,2,4-triazole 3-benzylsulfanyl derivatives.
2004 Apr
Synthesis and SAR evaluation of 1,2,4-triazoles as A(2A) receptor antagonists.
2004 Feb 9
Highly efficient and mild copper-catalyzed N- and C-arylations with aryl bromides and iodides.
2004 Nov 5
Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors.
2005 Dec 1
Energetic azolium azolate salts.
2005 Jul 11
4,4'-Butane-1,4-diylbis[3-ethyl-1H-1,2,4-triazol-5(4H)-one] and 4-hydroxy-3-n-propyl-1H-1,2,4-triazol-5(4H)-one.
2005 Jun
Metal ion coordination to azole nucleosides.
2005 Oct 21
Determination of 22 triazole compounds including parent fungicides and metabolites in apples, peaches, flour, and water by liquid chromatography/tandem mass spectrometry.
2005 Sep-Oct
Influence of garlic, synthetic 1,2,4-triasole derivative and herbal preparation echinovit C on selected indices of turkey-hens non-specific immunity.
2006
Synthesis, characterization, and in vitro antitumor properties of tris(hydroxymethyl)phosphine copper(I) complexes containing the new bis(1,2,4-triazol-1-yl)acetate ligand.
2006 Dec 14
Synthesis and CYP26A1 inhibitory activity of 1-[benzofuran-2-yl-(4-alkyl/aryl-phenyl)-methyl]-1H-triazoles.
2006 Jun 1
Synthesis and light-emitting properties of bipolar oligofluorenes containing triarylamine and 1,2,4-triazole moieties.
2006 Sep 14
Nondegenerate pi-donor/pi-acceptor [2]catenanes containing proton-ionizable 1H-1,2,4-triazole subunits: synthesis and spontaneous resolution.
2007
Synthesis of 1,2,4-triazole C-nucleosides from hydrazonyl chlorides and nitriles.
2007
Differential reactivity of alpha and beta 2'-deoxyribonucleosides towards protonation and metalation.
2007 Mar
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 17:32:27 GMT 2023
Edited
by admin
on Fri Dec 15 17:32:27 GMT 2023
Record UNII
10MS0Y1RDI
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
1H-1,2,4-TRIAZOLE
HSDB   MI  
Systematic Name English
EFINACONAZOLE METABOLITE H1
Common Name English
TRIAZOLE, 1H,1,2,4-
Common Name English
PYRRODIAZOLE
Common Name English
1H-1,2,4-TRIAZOLE [MI]
Common Name English
1H-1,2,4-TRIAZOLE [HSDB]
Common Name English
NSC-83128
Code English
Classification Tree Code System Code
EPA PESTICIDE CODE 600074
Created by admin on Fri Dec 15 17:32:27 GMT 2023 , Edited by admin on Fri Dec 15 17:32:27 GMT 2023
Code System Code Type Description
PUBCHEM
9257
Created by admin on Fri Dec 15 17:32:27 GMT 2023 , Edited by admin on Fri Dec 15 17:32:27 GMT 2023
PRIMARY
NSC
83128
Created by admin on Fri Dec 15 17:32:27 GMT 2023 , Edited by admin on Fri Dec 15 17:32:27 GMT 2023
PRIMARY
MERCK INDEX
m11036
Created by admin on Fri Dec 15 17:32:27 GMT 2023 , Edited by admin on Fri Dec 15 17:32:27 GMT 2023
PRIMARY Merck Index
DRUG BANK
DB03594
Created by admin on Fri Dec 15 17:32:27 GMT 2023 , Edited by admin on Fri Dec 15 17:32:27 GMT 2023
PRIMARY
CHEBI
35550
Created by admin on Fri Dec 15 17:32:27 GMT 2023 , Edited by admin on Fri Dec 15 17:32:27 GMT 2023
PRIMARY
WIKIPEDIA
1,2,4-Triazole
Created by admin on Fri Dec 15 17:32:27 GMT 2023 , Edited by admin on Fri Dec 15 17:32:27 GMT 2023
PRIMARY
FDA UNII
10MS0Y1RDI
Created by admin on Fri Dec 15 17:32:27 GMT 2023 , Edited by admin on Fri Dec 15 17:32:27 GMT 2023
PRIMARY
ECHA (EC/EINECS)
206-022-9
Created by admin on Fri Dec 15 17:32:27 GMT 2023 , Edited by admin on Fri Dec 15 17:32:27 GMT 2023
PRIMARY
HSDB
7860
Created by admin on Fri Dec 15 17:32:27 GMT 2023 , Edited by admin on Fri Dec 15 17:32:27 GMT 2023
PRIMARY
CAS
288-88-0
Created by admin on Fri Dec 15 17:32:27 GMT 2023 , Edited by admin on Fri Dec 15 17:32:27 GMT 2023
PRIMARY
EPA CompTox
DTXSID6027131
Created by admin on Fri Dec 15 17:32:27 GMT 2023 , Edited by admin on Fri Dec 15 17:32:27 GMT 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
Related Record Type Details
PARENT -> METABOLITE
PARENT -> METABOLITE
lacks pharmacologic activity
MAJOR