U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C4H8N2O3
Molecular Weight 132.1179
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIGLYCINE

SMILES

NCC(=O)NCC(O)=O

InChI

InChIKey=YMAWOPBAYDPSLA-UHFFFAOYSA-N
InChI=1S/C4H8N2O3/c5-1-3(7)6-2-4(8)9/h1-2,5H2,(H,6,7)(H,8,9)

HIDE SMILES / InChI

Molecular Formula C4H8N2O3
Molecular Weight 132.1179
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Electrochemical determination of gamma-glutamyl transpeptidase activity and its application to a miniaturized analysis system.
2006-01-15
Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription.
2005-07-27
Ab initio-based exciton model of amide I vibrations in peptides: definition, conformational dependence, and transferability.
2005-06-08
Validation of a colorimetric assay for the in vitro screening of inhibitors of angiotensin-converting enzyme (ACE) from plant extracts.
2005-06
Activity determination, kinetic analyses and isoenzyme identification of gamma glutamyltransferase in human neutrophils.
2005-05-31
Industrial-scale production and purification of a heterologous protein in Lactococcus lactis using the nisin-controlled gene expression system NICE: the case of lysostaphin.
2005-05-27
Montanide ISA 720 vaccines: quality control of emulsions, stability of formulated antigens, and comparative immunogenicity of vaccine formulations.
2005-03-31
Photooxidation of diglycine in confined media. Application of the microreactor model for spin-correlated radical pairs in reverse micelles and water-in-oil microemulsions.
2005-03-29
Solution structure of human SUMO-3 C47S and its binding surface for Ubc9.
2005-03-01
New triorganotin(IV) derivatives of dipeptides as anti-inflammatory-antimicrobial agents.
2005-03
Tyrphostins reduce chemotherapy-induced intestinal injury in mice: assessment by a biochemical assay.
2005-01-31
Enzyme hyperactivity in AOT water-in-oil microemulsions is induced by 'lone' sodium counterions in the water-pool.
2005
The Gly-Gly linker region of the insect cytokine growth-blocking peptide is essential for activity.
2004-12-03
Identification of sites of ubiquitination in proteins: a fourier transform ion cyclotron resonance mass spectrometry approach.
2004-12-01
A pH-stating mechanism in isolated wheat (Triticum aestivum) aleurone layers involves malic acid transport.
2004-12
On the mechanisms of oligopeptide reactions in solution and clay dispersion.
2004-12
Binding behavior of aliphatic oligopeptides by bridged and metallobridged bis(beta-cyclodextrin)s bearing an oxamido bis(2-benzoic) carboxyl linker.
2004-11-18
Catalytic transformations with copper-metalated diglycine conjugates.
2004-11-15
The Gly482Ser polymorphism in the peroxisome proliferator-activated receptor-gamma coactivator-1 gene is associated with hypertension in type 2 diabetic men.
2004-11
In vivo imaging of activated estrogen receptors in utero by estrogens and bisphenol A.
2004-11
Effect of dipeptides on the growth of Oenococcus oeni in synthetic medium deprived of amino acids.
2004-11
Prominent role of gamma-glutamyl-transpeptidase on the growth of Helicobacter pylori.
2004-10-15
A generic basis for some simple light-operated mechanical molecular machines.
2004-10-06
Chlorination byproduct formation in the presence of humic acid, model nitrogenous organic compounds, ammonia, and bromide.
2004-10-01
Method for enhancing solubility of the expressed recombinant proteins in Escherichia coli.
2004-09
[Thermochemistry of dissolving glycine, glycyl-glycine, and diglycyl-glycine in a mixed water-dimethylsulfoxide solvent at 298.15 K].
2004-08-26
Direct detection of biomolecules in a capillary electrophoresis-chemiluminescence detection system.
2004-08-01
A basis for SUMO protease specificity provided by analysis of human Senp2 and a Senp2-SUMO complex.
2004-08
Molecular modeling of dipeptide and its analogous systems with water.
2004-06
Modification of the furanacryloyl-L-phenylalanylglycylglycine assay for determination of angiotensin-I-converting enzyme inhibitory activity.
2004-05-31
Gas-phase H/D exchange of sodiated glycine oligomers with ND3: exchange kinetics do not reflect parent ion structures.
2004-05-26
Part I: surface-enhanced Raman spectroscopy investigation of amino acids and their homodipeptides adsorbed on colloidal silver.
2004-05
Inhibition of copper-catalyzed cysteine oxidation by nanomolar concentrations of iron salts.
2004-03-15
Synthesis of novel 3-pyridinecarbonitriles with amino acid function and their fluorescence properties.
2004-03
Additive transfer free energies of the peptide backbone unit that are independent of the model compound and the choice of concentration scale.
2004-02-10
Hydrated metal(II) complexes of N-(6-amino-3,4-dihydro-3-methyl-5-nitroso-4-oxopyrimidin-2-yl) derivatives of glycine, glycylglycine, threonine, serine, valine and methionine: a monomeric complex and coordination polymers in one, two and three dimensions linked by hydrogen bonding.
2004-02
A novel molecular ladder structure of Cu(II)-Ba(II) coordination polymer exhibiting ferromagnetic coupling.
2003-12-07
Direct dynamics study of N-protonated diglycine surface-induced dissociation. Influence of collision energy.
2003-12
Redox modulation of NF-kappaB nuclear translocation and DNA binding in metastatic melanoma. The role of endogenous and gamma-glutamyl transferase-dependent oxidative stress.
2003-11-11
Probing cathepsin K activity with a selective substrate spanning its active site.
2003-10-15
Bis(glycylglycinium) oxalate at 100 K.
2003-10
Elimination of water from the carboxyl group of GlyGlyH+.
2003-10
The bold legacy of Emil Fischer.
2003-09
Rotational resonance NMR: separation of dipolar coupling and zero quantum relaxation.
2003-09
Specificity of the action of lysoamidase on Staphylococcus aureus 209P cell walls.
2003-07
[Analysis of the growth system of Candida albicans in a host and the development of new antifungal material].
2003-07
N[bond]C(alpha) bond dissociation energies and kinetics in amide and peptide radicals. Is the dissociation a non-ergodic process?
2003-05-14
Metal-catalyzed hydroxylaminolysis of unactivated amide and peptide bonds.
2003-03-07
Molecular recognition in the gas phase ligand switching reactions of the proton bound dimer of sarcosine and glycylglycine.
2003-02-21
Metabolism of tetraglycine in isolated non-filtering rat kidneys.
2002
Patents

Patents

Substance Class Chemical
Created
by admin
on Mon Mar 31 18:25:08 GMT 2025
Edited
by admin
on Mon Mar 31 18:25:08 GMT 2025
Record UNII
10525P22U0
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DIPEPTIDE-15
INCI  
INCI  
Preferred Name English
DIGLYCINE
Common Name English
GLYCYLGLYCINE [MI]
Common Name English
GLYCYLGLYCINE
MI  
Systematic Name English
GLYCYL GLYCINE
Systematic Name English
DIGLYCINE [USP-RS]
Common Name English
NSC-49346
Code English
GLYCYL-GLYCINE
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C73539
Created by admin on Mon Mar 31 18:25:08 GMT 2025 , Edited by admin on Mon Mar 31 18:25:08 GMT 2025
Code System Code Type Description
DAILYMED
10525P22U0
Created by admin on Mon Mar 31 18:25:08 GMT 2025 , Edited by admin on Mon Mar 31 18:25:08 GMT 2025
PRIMARY
SMS_ID
100000078742
Created by admin on Mon Mar 31 18:25:08 GMT 2025 , Edited by admin on Mon Mar 31 18:25:08 GMT 2025
PRIMARY
EVMPD
SUB12510MIG
Created by admin on Mon Mar 31 18:25:08 GMT 2025 , Edited by admin on Mon Mar 31 18:25:08 GMT 2025
PRIMARY
CHEBI
356445
Created by admin on Mon Mar 31 18:25:08 GMT 2025 , Edited by admin on Mon Mar 31 18:25:08 GMT 2025
PRIMARY
RS_ITEM_NUM
1199308
Created by admin on Mon Mar 31 18:25:08 GMT 2025 , Edited by admin on Mon Mar 31 18:25:08 GMT 2025
PRIMARY
ECHA (EC/EINECS)
209-127-8
Created by admin on Mon Mar 31 18:25:08 GMT 2025 , Edited by admin on Mon Mar 31 18:25:08 GMT 2025
PRIMARY
RXCUI
1362904
Created by admin on Mon Mar 31 18:25:08 GMT 2025 , Edited by admin on Mon Mar 31 18:25:08 GMT 2025
PRIMARY RxNorm
NCI_THESAURUS
C81374
Created by admin on Mon Mar 31 18:25:08 GMT 2025 , Edited by admin on Mon Mar 31 18:25:08 GMT 2025
PRIMARY
CHEBI
24786
Created by admin on Mon Mar 31 18:25:08 GMT 2025 , Edited by admin on Mon Mar 31 18:25:08 GMT 2025
PRIMARY
MERCK INDEX
m5809
Created by admin on Mon Mar 31 18:25:08 GMT 2025 , Edited by admin on Mon Mar 31 18:25:08 GMT 2025
PRIMARY Merck Index
WIKIPEDIA
GLYCYLGLYCINE
Created by admin on Mon Mar 31 18:25:08 GMT 2025 , Edited by admin on Mon Mar 31 18:25:08 GMT 2025
PRIMARY
EPA CompTox
DTXSID90862194
Created by admin on Mon Mar 31 18:25:08 GMT 2025 , Edited by admin on Mon Mar 31 18:25:08 GMT 2025
PRIMARY
FDA UNII
10525P22U0
Created by admin on Mon Mar 31 18:25:08 GMT 2025 , Edited by admin on Mon Mar 31 18:25:08 GMT 2025
PRIMARY
NSC
49346
Created by admin on Mon Mar 31 18:25:08 GMT 2025 , Edited by admin on Mon Mar 31 18:25:08 GMT 2025
PRIMARY
CAS
556-50-3
Created by admin on Mon Mar 31 18:25:08 GMT 2025 , Edited by admin on Mon Mar 31 18:25:08 GMT 2025
PRIMARY
PUBCHEM
11163
Created by admin on Mon Mar 31 18:25:08 GMT 2025 , Edited by admin on Mon Mar 31 18:25:08 GMT 2025
PRIMARY
CHEBI
17201
Created by admin on Mon Mar 31 18:25:08 GMT 2025 , Edited by admin on Mon Mar 31 18:25:08 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP