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Details

Stereochemistry ACHIRAL
Molecular Formula C4H8N2O3
Molecular Weight 132.1179
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIGLYCINE

SMILES

NCC(=O)NCC(O)=O

InChI

InChIKey=YMAWOPBAYDPSLA-UHFFFAOYSA-N
InChI=1S/C4H8N2O3/c5-1-3(7)6-2-4(8)9/h1-2,5H2,(H,6,7)(H,8,9)

HIDE SMILES / InChI

Molecular Formula C4H8N2O3
Molecular Weight 132.1179
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Controls exerted by the Aib residue: helix formation and helix reversal.
2001
Buffer effects on electric signals of light-excited bacteriorhodopsin mutants.
2001
Fructose-6-phosphate aldolase is a novel class I aldolase from Escherichia coli and is related to a novel group of bacterial transaldolases.
2001 Apr 6
Nonlinear free energy relationship in the general-acid-catalyzed acylation of rat kidney gamma-glutamyl transpeptidase by a series of gamma-glutamyl anilide substrate analogues.
2001 Oct 23
Using a noncovalent protection strategy to enhance solid-phase synthesis.
2002
Batch-type chemiluminescence detection cell for sensitization and simplification of capillary electrophoresis.
2002 Aug 15
Synthesis of the pro-gly dipeptide alkene isostere using olefin cross-metathesis.
2002 Aug 23
Anchoring of surface proteins to the cell wall of Staphylococcus aureus. III. Lipid II is an in vivo peptidoglycan substrate for sortase-catalyzed surface protein anchoring.
2002 May 3
In vitro permeation of beta-lactam antibiotics across rat jejunum and its correlation with oral bioavailability in humans.
2002 Oct
Cytotoxic T lymphocyte epitope analogues containing cis- or trans-4-aminocyclohexanecarboxylic acid residues.
2002 Sep
Direct dynamics study of N-protonated diglycine surface-induced dissociation. Influence of collision energy.
2003 Dec
Retrofitting BACs with G418 resistance, luciferase, and oriP and EBNA-1 - new vectors for in vitro and in vivo delivery.
2003 Feb 3
Purification and some properties of lysostaphin, a glycylglycine endopeptidase from the culture liquid of Staphylococcus simulans biovar staphylolyticus.
2003 Jan
Redox modulation of NF-kappaB nuclear translocation and DNA binding in metastatic melanoma. The role of endogenous and gamma-glutamyl transferase-dependent oxidative stress.
2003 Jul-Aug
Production of enterolysin A by a raw milk enterococcal isolate exhibiting multiple virulence factors.
2003 Mar
Reinvestigation of the proposed folding and self-association of the Neuropeptide Head Activator.
2003 Mar
Plasmid relaxation induced by copper metalated diglycine conjugates under heterogeneous reaction conditions.
2003 Mar 10
Theanine, gamma-glutamylethylamide, is metabolized by renal phosphate-independent glutaminase.
2003 Mar 17
Mechanism and energetics of intramolecular hydrogen transfer in amide and peptide radicals and cation-radicals.
2003 Mar 19
gamma-Glutamyl transpeptidase catalyses the extracellular detoxification of cisplatin in a human cell line derived from the proximal convoluted tubule of the kidney.
2003 May
Bis(glycylglycinium) oxalate at 100 K.
2003 Oct
Elimination of water from the carboxyl group of GlyGlyH+.
2003 Oct
The bold legacy of Emil Fischer.
2003 Sep
A basis for SUMO protease specificity provided by analysis of human Senp2 and a Senp2-SUMO complex.
2004 Aug
Direct detection of biomolecules in a capillary electrophoresis-chemiluminescence detection system.
2004 Aug 1
A pH-stating mechanism in isolated wheat (Triticum aestivum) aleurone layers involves malic acid transport.
2004 Dec
On the mechanisms of oligopeptide reactions in solution and clay dispersion.
2004 Dec
Identification of sites of ubiquitination in proteins: a fourier transform ion cyclotron resonance mass spectrometry approach.
2004 Dec 1
Hydrated metal(II) complexes of N-(6-amino-3,4-dihydro-3-methyl-5-nitroso-4-oxopyrimidin-2-yl) derivatives of glycine, glycylglycine, threonine, serine, valine and methionine: a monomeric complex and coordination polymers in one, two and three dimensions linked by hydrogen bonding.
2004 Feb
Molecular modeling of dipeptide and its analogous systems with water.
2004 Jun
Part I: surface-enhanced Raman spectroscopy investigation of amino acids and their homodipeptides adsorbed on colloidal silver.
2004 May
Modification of the furanacryloyl-L-phenylalanylglycylglycine assay for determination of angiotensin-I-converting enzyme inhibitory activity.
2004 May 31
[Thermochemistry of dissolving glycine, glycyl-glycine, and diglycyl-glycine in a mixed water-dimethylsulfoxide solvent at 298.15 K].
2004 May-Jun
Tyrphostins reduce chemotherapy-induced intestinal injury in mice: assessment by a biochemical assay.
2005 Jan 31
Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription.
2005 Jul 27
Validation of a colorimetric assay for the in vitro screening of inhibitors of angiotensin-converting enzyme (ACE) from plant extracts.
2005 Jun
Photooxidation of diglycine in confined media. Application of the microreactor model for spin-correlated radical pairs in reverse micelles and water-in-oil microemulsions.
2005 Mar 29
Patents

Patents

Substance Class Chemical
Created
by admin
on Fri Dec 15 16:19:31 GMT 2023
Edited
by admin
on Fri Dec 15 16:19:31 GMT 2023
Record UNII
10525P22U0
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DIGLYCINE
Common Name English
GLYCYLGLYCINE [MI]
Common Name English
GLYCYLGLYCINE
MI  
Systematic Name English
GLYCYL GLYCINE
Systematic Name English
DIPEPTIDE-15
INCI  
INCI  
Official Name English
DIPEPTIDE-15 [INCI]
Common Name English
DIGLYCINE [USP-RS]
Common Name English
NSC-49346
Code English
GLYCYL-GLYCINE
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C73539
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
Code System Code Type Description
DAILYMED
10525P22U0
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
SMS_ID
100000078742
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
EVMPD
SUB12510MIG
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
CHEBI
356445
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
RS_ITEM_NUM
1199308
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
ECHA (EC/EINECS)
209-127-8
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
RXCUI
1362904
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY RxNorm
NCI_THESAURUS
C81374
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
CHEBI
24786
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
MERCK INDEX
m5809
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY Merck Index
WIKIPEDIA
GLYCYLGLYCINE
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
EPA CompTox
DTXSID90862194
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
FDA UNII
10525P22U0
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
NSC
49346
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
CAS
556-50-3
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
PUBCHEM
11163
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
CHEBI
17201
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP