PD-161374

CC[C@H](C)[C@H](N1SC2=C(C=CC=C2)C1=O)C(O)=O

InChIKey=FUSYFEXGXRDJNB-KWQFWETISA-N

InChI=1S/C13H15NO3S/c1-3-8(2)11(13(16)17)14-12(15)9-6-4-5-7-10(9)18-14/h4-8,11H,3H2,1-2H3,(H,16,17)/t8-,11-/m0/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

PubMed

Title	Date	PubMed
Inhibition of the early phase of HIV replication by an isothiazolone, PD 161374.	2001-02	11248362
2,2'-Dithiobisbenzamides and 2-benzisothiazolones, two new classes of antiretroviral agents: SAR and mechanistic considerations.	1997-05	9332831
The human immunodeficiency virus type 1 (HIV-1) nucleocapsid protein zinc ejection activity of disulfide benzamides and benzisothiazolones: correlation with anti-HIV and virucidal activities.	1997-02	9021197

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:00:32 GMT 2025` Edited by `admin` on `Mon Mar 31 18:00:32 GMT 2025`
Record UNII	103QB0867Q
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

1,2-BENZISOTHIAZOLE-2(3H)-ACETIC ACID, .ALPHA.-((1S)-1-METHYLPROPYL)-3-OXO-, (.ALPHA.S)-

Preferred Name

English

PD-161374

Code

English

A-(1-METHYLPROPYL)-3-OXO-1,2-BENZOISOTHIAZOLE-2(3H)-ACETIC ACID, S-(R*,R*)

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID3047261

Created by admin on Mon Mar 31 18:00:32 GMT 2025 , Edited by admin on Mon Mar 31 18:00:32 GMT 2025

PRIMARY

PUBCHEM

462368

Created by admin on Mon Mar 31 18:00:32 GMT 2025 , Edited by admin on Mon Mar 31 18:00:32 GMT 2025

PRIMARY

CAS

177785-47-6

Created by admin on Mon Mar 31 18:00:32 GMT 2025 , Edited by admin on Mon Mar 31 18:00:32 GMT 2025

PRIMARY

FDA UNII

103QB0867Q

Created by admin on Mon Mar 31 18:00:32 GMT 2025 , Edited by admin on Mon Mar 31 18:00:32 GMT 2025

PRIMARY