Trastuzumab Rezetecan

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 16:17:35 GMT 2023` Edited by `admin` on `Sat Dec 16 16:17:35 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type	IGG1
Sequence Type	COMPLETE
Record UNII	1000BJC8CR
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Trastuzumab Rezetecan

Official Name

English

Immunoglobulin G1, anti-(human epidermal growth factor receptor HER2) (human-Mus musculus monoclonal SHR-1805 γ1-chain), complex with human-Mus musculus monoclonal SHR-1805 κ-chain, dimer, thioether with N-[6-(3-mercapto-2,5-dioxo-1-pyrrolidinyl)-1-oxo

Common Name

English

SHR A1811 [WHO-DD]

Code

English

immunoglobulin G1-kappa, anti-[Homo sapiens ERBB2 (epidermal growth factor receptor 2, receptor tyrosine-protein kinase erbB-2, EGFR2, HER2, HER-2, p185c-erbB2, NEU, CD340)], humanized monoclonal antibody, conjugated via a cleavable linker with a camptot

Common Name

English

trastuzumab rezetecan [INN]

Common Name

English

Code System Code Type Description

FDA UNII

1000BJC8CR

Created by admin on Sat Dec 16 16:17:35 GMT 2023 , Edited by admin on Sat Dec 16 16:17:35 GMT 2023

PRIMARY

NCI_THESAURUS

C178312

Created by admin on Sat Dec 16 16:17:35 GMT 2023 , Edited by admin on Sat Dec 16 16:17:35 GMT 2023

PRIMARY

INN

12243

Created by admin on Sat Dec 16 16:17:35 GMT 2023 , Edited by admin on Sat Dec 16 16:17:35 GMT 2023

PRIMARY

CAS

2647845-11-0

Created by admin on Sat Dec 16 16:17:35 GMT 2023 , Edited by admin on Sat Dec 16 16:17:35 GMT 2023

PRIMARY

From	To
4_134	4_194
4_23	4_88
3_134	3_194
3_23	3_88
2_370	2_428
2_264	2_324
2_147	2_203
2_22	2_96
1_370	1_428
1_264	1_324
1_147	1_203
1_22	1_96

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_300
N	2_300

Related Record Type Details


					1000BJC8CR

Trastuzumab Rezetecan

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL

Molecular Formula	CHEMICAL