ISOIMPERATORIN

CC(C)=CCOC1=C2C=CC(=O)OC2=CC3=C1C=CO3

InChIKey=IGWDEVSBEKYORK-UHFFFAOYSA-N

InChI=1S/C16H14O4/c1-10(2)5-7-19-16-11-3-4-15(17)20-14(11)9-13-12(16)6-8-18-13/h3-6,8-9H,7H2,1-2H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Mechanism-based inactivation of cytochrome P450 2B6 by isoimperatorin.	2015-01-25	25500267
Furocoumarins affect hepatic cytochrome P450 and renal organic ion transporters in mice.	2012-02-25	22173200
Notopterygium forbesii Boiss extract and its active constituent phenethyl ferulate attenuate pro-inflammatory responses to lipopolysaccharide in RAW 264.7 macrophages. A "protective" role for oxidative stress?	2009-08	19642688
The effects of isoimperatorin isolated from Angelicae dahuricae on cyclooxygenase-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells.	2008-02	18365692
Potent protective effect of isoimperatorin against aflatoxin B1-inducible cytotoxicity in H4IIE cells: bifunctional effects on glutathione S-transferase and CYP1A.	2006-12	16829687
Coumarins are competitive inhibitors of cytochrome P450 1B1, with equal potency for allelic variants.	2005-03	15861043
Suksdorfin: an anti-HIV principle from Lomatium suksdorfii, its structure-activity correlation with related coumarins, and synergistic effects with anti-AIDS nucleosides.	1994-10	7773621

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:58:05 GMT 2025` Edited by `admin` on `Mon Mar 31 19:58:05 GMT 2025`
Record UNII	0ZMV066080
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

7H-FURO(3,2-G)(1)BENZOPYRAN-7-ONE, 4-((3-METHYL-2-BUTENYL)OXY)-

Preferred Name

English

ISOIMPERATORIN

Common Name

English

Code System Code Type Description

PUBCHEM

68081

Created by admin on Mon Mar 31 19:58:05 GMT 2025 , Edited by admin on Mon Mar 31 19:58:05 GMT 2025

PRIMARY

FDA UNII

0ZMV066080

Created by admin on Mon Mar 31 19:58:05 GMT 2025 , Edited by admin on Mon Mar 31 19:58:05 GMT 2025

PRIMARY

EPA CompTox

DTXSID60197460

Created by admin on Mon Mar 31 19:58:05 GMT 2025 , Edited by admin on Mon Mar 31 19:58:05 GMT 2025

PRIMARY

CAS

482-45-1

Created by admin on Mon Mar 31 19:58:05 GMT 2025 , Edited by admin on Mon Mar 31 19:58:05 GMT 2025

PRIMARY

Related Record Type Details


					DTN01M69SN

PARENT -> CONSTITUENT ALWAYS PRESENT