Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C18H14F3N3O2S |
| Molecular Weight | 393.383 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CS(=O)(=O)C1=CC=C(C=C1)C2=CC(C3=CC=C(N=C3)C(F)(F)F)=C(N)N=C2
InChI
InChIKey=RTJQABCNNLMCJF-UHFFFAOYSA-N
InChI=1S/C18H14F3N3O2S/c1-27(25,26)14-5-2-11(3-6-14)13-8-15(17(22)24-10-13)12-4-7-16(23-9-12)18(19,20)21/h2-10H,1H3,(H2,22,24)
| Molecular Formula | C18H14F3N3O2S |
| Molecular Weight | 393.383 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Synthesis of 4-aminoquinoline-pyrimidine hybrids as potent antimalarials and their mode of action studies. | 2013 Aug |
|
| Cell-based medicinal chemistry optimization of high throughput screening hits for orally active antimalarials. Part 2: hits from SoftFocus kinase and other libraries. | 2013 Oct 24 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 18:31:39 GMT 2023
by
admin
on
Sat Dec 16 18:31:39 GMT 2023
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| Record UNII |
0Z5T00JJ10
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| Record Status |
Validated (UNII)
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| Record Version |
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0Z5T00JJ10
Created by
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53311393
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1314883-11-8
Created by
admin on Sat Dec 16 18:31:40 GMT 2023 , Edited by admin on Sat Dec 16 18:31:40 GMT 2023
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TARGET ORGANISM->INHIBITOR |
Whole-cell blood stage activity of UCT943 against a panel of resistant P. falciparum strains to determine potential for cross-resistance compared with MMV048, chloroquine (CQ) and artesunate (AS)
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ACTIVE MOIETY |
