Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C18H14F3N3O2S |
| Molecular Weight | 393.383 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CS(=O)(=O)C1=CC=C(C=C1)C2=CN=C(N)C(=C2)C3=CN=C(C=C3)C(F)(F)F
InChI
InChIKey=RTJQABCNNLMCJF-UHFFFAOYSA-N
InChI=1S/C18H14F3N3O2S/c1-27(25,26)14-5-2-11(3-6-14)13-8-15(17(22)24-10-13)12-4-7-16(23-9-12)18(19,20)21/h2-10H,1H3,(H2,22,24)
| Molecular Formula | C18H14F3N3O2S |
| Molecular Weight | 393.383 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Cell-based medicinal chemistry optimization of high throughput screening hits for orally active antimalarials. Part 2: hits from SoftFocus kinase and other libraries. | 2013-10-24 |
|
| Synthesis of 4-aminoquinoline-pyrimidine hybrids as potent antimalarials and their mode of action studies. | 2013-08 |
|
| 3,5-Diaryl-2-aminopyridines as a novel class of orally active antimalarials demonstrating single dose cure in mice and clinical candidate potential. | 2012-04-12 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Apr 02 11:26:09 GMT 2025
by
admin
on
Wed Apr 02 11:26:09 GMT 2025
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| Record UNII |
0Z5T00JJ10
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| Record Status |
Validated (UNII)
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300000046528
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1314883-11-8
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TARGET ORGANISM->INHIBITOR |
Whole-cell blood stage activity of UCT943 against a panel of resistant P. falciparum strains to determine potential for cross-resistance compared with MMV048, chloroquine (CQ) and artesunate (AS)
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ACTIVE MOIETY |
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