FLUDEOXYGLUCOSE F-18

First approved in 1994

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C6H11FO5
Molecular Weight	181.1495
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H]([18F])C=O

InChI

InChIKey=AOYNUTHNTBLRMT-MXWOLSILSA-N

InChI=1S/C6H11FO5/c7-3(1-8)5(11)6(12)4(10)2-9/h1,3-6,9-12H,2H2/t3-,4+,5+,6+/m0/s1/i7-1

HIDE SMILES / InChI

Molecular Formula	C6H11FO5
Molecular Weight	181.1495
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021870s007lbl.pdf

Fludeoxyglucose F-18 is a positron emitting radiopharmaceutical that is used for diagnostic purposes in conjunction with positron emission tomography (PET) imaging.

CNS Activity

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
glucose metabolic process 4 Target ID: GO:0006006 Sources: http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021870s007lbl.pdf	Interacts 323

Conditions

Condition	Modality	Highest Phase	Product
Cancer 592 Sources: http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021870s007lbl.pdf	Diagnostic	Approved 8429	FLUDEOXYGLUCOSE F18 Approved Use For positron emission tomography (PET) imaging in oncology, cardiology, neurology. Launch Date 2005
Coronary artery disease 48 Sources: http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021870s007lbl.pdf	Diagnostic	Approved 8429	FLUDEOXYGLUCOSE F18 Approved Use For positron emission tomography (PET) imaging in oncology, cardiology, neurology. Launch Date 2005
Left ventricular dysfunction 4 Sources: http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021870s007lbl.pdf	Diagnostic	Approved 8429	FLUDEOXYGLUCOSE F18 Approved Use For positron emission tomography (PET) imaging in oncology, cardiology, neurology. Launch Date 2005
Epileptic seizures 3 Sources: http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021870s007lbl.pdf	Diagnostic	Approved 8429	FLUDEOXYGLUCOSE F18 Approved Use For positron emission tomography (PET) imaging in oncology, cardiology, neurology. Launch Date 2005

PubMed

Title	Date	PubMed
A shielded synthesis system for production of 2-deoxy-2-[18F]fluoro-D-glucose.	1981 Apr	7205386
Metabolic mapping of functional activity in human subjects with the [18F]fluorodeoxyglucose technique.	1981 May 8	6971492
Disseminated histoplasmosis demonstrated on F18-fluorodeoxyglucose positron emission tomography/computed tomography in a renal transplant recipient.	2016 Apr-Jun	27095874
Future imaging of atherosclerosis: molecular imaging of coronary atherosclerosis with (18)F positron emission tomography.	2016 Aug	27500093
Impact of (18)FDG PET and (11)C-PIB PET brain imaging on the diagnosis of Alzheimer's disease and other dementias in a regional memory clinic in Hong Kong.	2016 Aug	27313272

Sample Use Guides

In Vivo Use Guide

5 – 10 mCi (adults), 2.6 mCi (pediatric patients)

Route of Administration: Intravenous

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:30:47 GMT 2023` Edited by `admin` on `Fri Dec 15 15:30:47 GMT 2023`
Record UNII	0Z5B2CJX4D
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FLUDEOXYGLUCOSE F-18

Common Name

English

FLUGLUCOSCAN

Brand Name

English

18-F FDG

Common Name

English

FLUDEOXYGLUCOSE F 18 [VANDF]

Common Name

English

(18F)-FDG

Common Name

English

FLUORODEOXYGLUCOSE F18

Common Name

English

FLUDEOXYGLUCOSE (18F)

Official Name

English

FLUDEOXYGLUCOSE F 18 [USAN]

Common Name

English

(18F)FLUORODEOXYGLUCOSE

Common Name

English

FLUDEOXYGLUCOSE F-18 [ORANGE BOOK]

Common Name

English

S8FDG

Code

English

Fludeoxyglucose (18f) [WHO-DD]

Common Name

English

(18F)FLUORO-2-DEOXYGLUCOSE

Common Name

English

FLUDEOXYGLUCOSE F 18

Official Name

English

18F-FDG

Common Name

English

FLUDEOXYGLUCOSE F(SUP 18) [MI]

Common Name

English

18F-FLUORODEOXYGLUCOSE

Common Name

English

FLUDEOXYGLUCOSE, F-18

Common Name

English

FLUDEOXYGLUCOSE ((SUP 18)F)

Common Name

English

(18F)-FLUORODEOXYGLUCOSE

Common Name

English

fludeoxyglucose (¹⁸F) [INN]

Common Name

English

2-DEOXY-2-(FLUORO-18F)-D-GLUCOSE

Systematic Name

English

FLUDEOXYGLUCOSE (18F) [JAN]

Common Name

English

18-FDG

Code

English

2-DEOXY-2-(18F)FLUORO-D-GLUCOSE

Common Name

English

FDG F-18

Common Name

English

FLUDEOXYGLUCOSE F18

Brand Name

English

D-GLUCOSE, 2-DEOXY-2-(FLUORO-18F)-

Systematic Name

English

FLUDEOXYGLUCOSE F 18 [MI]

Common Name

English

FLUORINE (18F) FLUDEOXYGLUCOSE

Common Name

English

FDG-PET

Common Name

English

FLUDEOXYGLUCOSE F 18 [USP IMPURITY]

Common Name

English

2-DEOXY-2-FLUORO-D-GLUCOSE, F-18

Common Name

English

(18F)FDG

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C2124

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

WHO-VATC

QV09IX04

Created by admin on Fri Dec 15 15:30:48 GMT 2023 , Edited by admin on Fri Dec 15 15:30:48 GMT 2023

NDF-RT

N0000177914

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

WHO-ATC

V09IX04

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

NDF-RT

N0000000205

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

Code System Code Type Description

DRUG BANK

DB09150

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

PRIMARY

DRUG CENTRAL

4455

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

PRIMARY

CHEBI

49134

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

PRIMARY

NCI_THESAURUS

C964

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

PRIMARY

CHEBI

31617

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

PRIMARY

CAS

105851-17-0

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

ALTERNATIVE

DAILYMED

0Z5B2CJX4D

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

PRIMARY

EPA CompTox

DTXSID40212908

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

PRIMARY

WIKIPEDIA

FLUDEOXYGLUCOSE (18F)

Created by admin on Fri Dec 15 15:30:48 GMT 2023 , Edited by admin on Fri Dec 15 15:30:48 GMT 2023

PRIMARY

SMS_ID

100000092614

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

PRIMARY

INN

6446

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

PRIMARY

ChEMBL

CHEMBL1235932

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

PRIMARY

RXCUI

1362737

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

PRIMARY

RxNorm

CAS

63503-12-8

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

PRIMARY

PUBCHEM

68614

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

PRIMARY

MERCK INDEX

m5428

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

PRIMARY

EVMPD

SUB07680MIG

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

PRIMARY

USAN

AA-83

Created by admin on Fri Dec 15 15:30:48 GMT 2023 , Edited by admin on Fri Dec 15 15:30:48 GMT 2023

PRIMARY

LACTMED

Fludeoxyglucose F18

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

PRIMARY

FDA UNII

0Z5B2CJX4D

Created by admin on Fri Dec 15 15:30:47 GMT 2023 , Edited by admin on Fri Dec 15 15:30:47 GMT 2023

PRIMARY

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ACTIVE MOIETY

Amount:

Details

SMILES

InChI

DescriptionSources: http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021870s007lbl.pdf

CNS Activity

Originator

Approval Year

Targets

Conditions

Approved Use

Launch Date

Approved Use

Launch Date

Approved Use

Launch Date

Approved Use

Launch Date

PubMed

Sample Use Guides

Description
Sources: http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021870s007lbl.pdf