ISOQUERCITRIN

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H20O12
Molecular Weight	464.3763
Optical Activity	UNSPECIFIED
Defined Stereocenters	5 / 5
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]1(O[C@@H](OC2=C(OC3=C(C2=O)C(O)=CC(O)=C3)C4=CC=C(O)C(O)=C4)[C@H](O)[C@H]1O)[C@H](O)CO

InChI

InChIKey=OPJZLUXFQFQYAI-GNPVFZCLSA-N

InChI=1S/C21H20O12/c22-6-12(27)19-16(29)17(30)21(32-19)33-20-15(28)14-11(26)4-8(23)5-13(14)31-18(20)7-1-2-9(24)10(25)3-7/h1-5,12,16-17,19,21-27,29-30H,6H2/t12-,16-,17-,19-,21+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C21H20O12
Molecular Weight	464.3763
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	5 / 5
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Potency
Wnt signaling pathway 12 Target ID: GO:0016055 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25359775	Inhibitor 8228
Aldose reductase 44 Target ID: CHEMBL1900 Sources: https://www.ncbi.nlm.nih.gov/pubmed/22261024	Inhibitor 8228	4.5 µM [IC50]
Arginase 1 Target ID: CHEMBL3108635 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24521209	Inhibitor 8228	2.0 µM [IC50]
Carbonic anhydrase VII 36 Target ID: CHEMBL2326 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26498393	Inhibitor 8228	3.8 nM [IC50]

PubMed

Title	Date	PubMed
Inhibitory effects of Egyptian folk medicines on human immunodeficiency virus (HIV) reverse transcriptase.	1995 Apr	7541317
[Chemical constituents from the leaves of crataegus pinnatifida Bge. var. major N.E.Br].	2001 Oct	12579975
[HPLC investigation of antioxidant components in Solidago herba].	2004	16316050
[Applications of two-dimensional liquid chromatography coupled to mass spectrometry for the separation and identification of compounds in ginkgo biloba extracts].	2005 Jan	15881366
[Study on chemical constituents of Lagotis yunnanensis].	2005 Sep	16447867
Inhibition of human cytochrome CYP 1 enzymes by flavonoids of St. John's wort.	2006 Jan 16	16271822
[Isolation and preparation of flavones from the leaves of Lindera aggregata using high speed counter-current chromatography].	2007 Sep	18161329
Camellia japonica suppresses immunoglobulin E-mediated allergic response by the inhibition of Syk kinase activation in mast cells.	2008 May	18261158
[Flavones from flowers of Paulownia fortunei].	2008 Nov	19216158
Phytochemicals of apple peels: isolation, structure elucidation, and their antiproliferative and antioxidant activities.	2008 Nov 12	18828600
Chemical composition of the stem bark and leaves of Ficus pandurata Hance.	2009	19731141
Antioxidant enzymatically modified isoquercitrin suppresses the development of liver preneoplastic lesions in rats induced by beta-naphthoflavone.	2010 Feb 9	20045035
Concomitant apoptosis and regeneration of liver cells as a mechanism of liver-tumor promotion by β-naphthoflavone involving TNFα-signaling due to oxidative cellular stress in rats.	2011 Apr 28	21295105
Screening medicinal plants for the detection of novel antimalarial products applying the inhibition of β-hematin formation.	2011 Dec 15	21872416

Patents

Substance Class	Chemical Created by `admin` on `Thu Jul 06 02:42:51 UTC 2023` Edited by `admin` on `Thu Jul 06 02:42:51 UTC 2023`
Record UNII	0YX10VRV6J
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ISOQUERCITRIN

Official Name

English

QUERCETIN 3-O-.BETA.-D-GLUCOFURANOSIDE

Common Name

English

FEMA NO. 4225

Code

English

ISOQUERCITRIN [INCI]

Common Name

English

FLAVONE, 3,3',4',5,7-PENTAHYDROXY-, 3-.BETA.-D-GLUCOFURANOSIDE

Common Name

English

QUERCETIN 3-(.BETA.-D-GLUCOFURANOSIDE)

Common Name

English

ISOTRIFOLIN

Common Name

English

ISOQUERCITROSIDE

Common Name

English

ISOQUERCETIN ENZYMATICALLY MODIFIED [FHFI]

Common Name

English

4H-1-BENZOPYRAN-4-ONE, 2-(3,4-DIHYDROXYPHENYL)-3-(.BETA.-D-GLUCOFURANOSYLOXY)-5,7-DIHYDROXY-

Common Name

English

ISOTRIFOLIIN

Common Name

English

Classification Tree Code System Code

DSLD

3889 (Number of products:4)