Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C21H20O12 |
Molecular Weight | 464.3763 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 5 / 5 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]1(O[C@@H](OC2=C(OC3=C(C2=O)C(O)=CC(O)=C3)C4=CC=C(O)C(O)=C4)[C@H](O)[C@H]1O)[C@H](O)CO
InChI
InChIKey=OPJZLUXFQFQYAI-GNPVFZCLSA-N
InChI=1S/C21H20O12/c22-6-12(27)19-16(29)17(30)21(32-19)33-20-15(28)14-11(26)4-8(23)5-13(14)31-18(20)7-1-2-9(24)10(25)3-7/h1-5,12,16-17,19,21-27,29-30H,6H2/t12-,16-,17-,19-,21+/m1/s1
Molecular Formula | C21H20O12 |
Molecular Weight | 464.3763 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 5 / 5 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: GO:0016055 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25359775 |
|||
Target ID: CHEMBL1900 Sources: https://www.ncbi.nlm.nih.gov/pubmed/22261024 |
4.5 µM [IC50] | ||
Target ID: CHEMBL3108635 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24521209 |
2.0 µM [IC50] | ||
Target ID: CHEMBL2326 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26498393 |
3.8 nM [IC50] |
PubMed
Title | Date | PubMed |
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Inhibitory effects of Egyptian folk medicines on human immunodeficiency virus (HIV) reverse transcriptase. | 1995 Apr |
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[Chemical constituents from the leaves of crataegus pinnatifida Bge. var. major N.E.Br]. | 2001 Oct |
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[HPLC investigation of antioxidant components in Solidago herba]. | 2004 |
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[Applications of two-dimensional liquid chromatography coupled to mass spectrometry for the separation and identification of compounds in ginkgo biloba extracts]. | 2005 Jan |
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[Study on chemical constituents of Lagotis yunnanensis]. | 2005 Sep |
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Inhibition of human cytochrome CYP 1 enzymes by flavonoids of St. John's wort. | 2006 Jan 16 |
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[Isolation and preparation of flavones from the leaves of Lindera aggregata using high speed counter-current chromatography]. | 2007 Sep |
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Camellia japonica suppresses immunoglobulin E-mediated allergic response by the inhibition of Syk kinase activation in mast cells. | 2008 May |
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[Flavones from flowers of Paulownia fortunei]. | 2008 Nov |
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Phytochemicals of apple peels: isolation, structure elucidation, and their antiproliferative and antioxidant activities. | 2008 Nov 12 |
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Chemical composition of the stem bark and leaves of Ficus pandurata Hance. | 2009 |
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Antioxidant enzymatically modified isoquercitrin suppresses the development of liver preneoplastic lesions in rats induced by beta-naphthoflavone. | 2010 Feb 9 |
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Concomitant apoptosis and regeneration of liver cells as a mechanism of liver-tumor promotion by β-naphthoflavone involving TNFα-signaling due to oxidative cellular stress in rats. | 2011 Apr 28 |
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Screening medicinal plants for the detection of novel antimalarial products applying the inhibition of β-hematin formation. | 2011 Dec 15 |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Thu Jul 06 02:42:51 UTC 2023
by
admin
on
Thu Jul 06 02:42:51 UTC 2023
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Record UNII |
0YX10VRV6J
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Record Status |
Validated (UNII)
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Record Version |
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Classification Tree | Code System | Code | ||
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DSLD |
3889 (Number of products:4)
Created by
admin on Thu Jul 06 02:42:51 UTC 2023 , Edited by admin on Thu Jul 06 02:42:51 UTC 2023
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NCI_THESAURUS |
C270
Created by
admin on Thu Jul 06 02:42:51 UTC 2023 , Edited by admin on Thu Jul 06 02:42:51 UTC 2023
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Code System | Code | Type | Description | ||
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C016527
Created by
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28299
Created by
admin on Thu Jul 06 02:42:51 UTC 2023 , Edited by admin on Thu Jul 06 02:42:51 UTC 2023
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PRIMARY | |||
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Isoquercitrin
Created by
admin on Thu Jul 06 02:42:51 UTC 2023 , Edited by admin on Thu Jul 06 02:42:51 UTC 2023
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DTXSID80904976
Created by
admin on Thu Jul 06 02:42:51 UTC 2023 , Edited by admin on Thu Jul 06 02:42:51 UTC 2023
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21637-25-2
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C99879
Created by
admin on Thu Jul 06 02:42:51 UTC 2023 , Edited by admin on Thu Jul 06 02:42:51 UTC 2023
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PRIMARY | |||
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5484006
Created by
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PRIMARY | |||
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0YX10VRV6J
Created by
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244-488-5
Created by
admin on Thu Jul 06 02:42:51 UTC 2023 , Edited by admin on Thu Jul 06 02:42:51 UTC 2023
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PRIMARY | |||
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68352
Created by
admin on Thu Jul 06 02:42:51 UTC 2023 , Edited by admin on Thu Jul 06 02:42:51 UTC 2023
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PRIMARY |
Related Record | Type | Details | ||
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PARENT -> IMPURITY |
NMT 2%
USP
|