ISOQUERCITRIN

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H20O12
Molecular Weight	464.3763
Optical Activity	UNSPECIFIED
Defined Stereocenters	5 / 5
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]1(O[C@@H](OC2=C(OC3=C(C2=O)C(O)=CC(O)=C3)C4=CC=C(O)C(O)=C4)[C@H](O)[C@H]1O)[C@H](O)CO

InChI

InChIKey=OPJZLUXFQFQYAI-GNPVFZCLSA-N

InChI=1S/C21H20O12/c22-6-12(27)19-16(29)17(30)21(32-19)33-20-15(28)14-11(26)4-8(23)5-13(14)31-18(20)7-1-2-9(24)10(25)3-7/h1-5,12,16-17,19,21-27,29-30H,6H2/t12-,16-,17-,19-,21+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C21H20O12
Molecular Weight	464.3763
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	5 / 5
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Potency
Wnt signaling pathway 13 Target ID: GO:0016055 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25359775	Inhibitor 8297
Aldose reductase 44 Target ID: CHEMBL1900 Sources: https://www.ncbi.nlm.nih.gov/pubmed/22261024	Inhibitor 8297	4.5 µM [IC50]
Arginase 1 Target ID: CHEMBL3108635 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24521209	Inhibitor 8297	2.0 µM [IC50]
Carbonic anhydrase VII 34 Target ID: CHEMBL2326 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26498393	Inhibitor 8297	3.8 nM [IC50]

PubMed

Title	Date	PubMed
Inhibition of HIV infection by flavanoids.	1993 Oct	8279812
Inhibitory effects of Egyptian folk medicines on human immunodeficiency virus (HIV) reverse transcriptase.	1995 Apr	7541317
Inhibitory effects of sudanese medicinal plant extracts on hepatitis C virus (HCV) protease.	2000 Nov	11054840
Antioxidative components from the aerial parts of Lactuca scariola L.	2001 Oct	11693545
Antioxidant and photoprotective activity of a crude extract of Culcitium reflexum H.B.K. leaves and their major flavonoids.	2002 Feb	11801380
The inhibitory effects of 12 medicinal plants and their component compounds on lipid peroxidation.	2003	14992543
Depsides from the petals of Papaver rhoeas.	2004 Apr	15095160
Characterization of flavonols in cranberry (Vaccinium macrocarpon) powder.	2004 Jan 28	14733493
[Study on chemical constituents of Lagotis yunnanensis].	2005 Sep	16447867
[Studies on chemical constituents from flowers of Apocynum venetum].	2005 Sep	16323543
Development of an HPLC-PAD-MS assay for the identification and quantification of major phenolic edelweiss (Leontopodium alpium Cass.) constituents.	2006 Sep-Oct	17019930
[Studies on chemical constituents of Primula sikkmensis].	2008 Jan	18589747
Soil quality effects on Chenopodium album flavonoid content and antioxidant potential.	2008 Jul 9	18553886
Determination of the relative contribution of quercetin and its glucosides to the antioxidant capacity of onion by cyclic voltammetry and spectrophotometric methods.	2008 May 28	18454541
Deep supercooling xylem parenchyma cells of katsura tree (Cercidiphyllum japonicum) contain flavonol glycosides exhibiting high anti-ice nucleation activity.	2008 Sep	18518920
[Chemical study on ethyl acetate soluble portion of Kadsura oblongifolia].	2009 Apr	19623983
[Flavonoid constituents from herbs of Sarcopyramis bodinieri var. delicata].	2009 Jan	19385178
Preparative isolation and purification of four flavonoids from the petals of Nelumbo nucifera by high-speed counter-current chromatography.	2010 May-Jun	20020439
Effect of enzymatically modified isoquercitrin on preneoplastic liver cell lesions induced by thioacetamide promotion in a two-stage hepatocarcinogenesis model using rats.	2013 Mar 8	23318833

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:39:40 GMT 2023` Edited by `admin` on `Fri Dec 15 19:39:40 GMT 2023`
Record UNII	0YX10VRV6J
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ISOQUERCITRIN

Official Name

English

QUERCETIN 3-O-.BETA.-D-GLUCOFURANOSIDE

Common Name

English

FEMA NO. 4225

Code

English

ISOQUERCITRIN [INCI]

Common Name

English

FLAVONE, 3,3',4',5,7-PENTAHYDROXY-, 3-.BETA.-D-GLUCOFURANOSIDE

Common Name

English

QUERCETIN 3-(.BETA.-D-GLUCOFURANOSIDE)

Common Name

English

ISOTRIFOLIN

Common Name

English

ISOQUERCITROSIDE

Common Name

English

ISOQUERCETIN ENZYMATICALLY MODIFIED [FHFI]

Common Name

English

4H-1-BENZOPYRAN-4-ONE, 2-(3,4-DIHYDROXYPHENYL)-3-(.BETA.-D-GLUCOFURANOSYLOXY)-5,7-DIHYDROXY-

Common Name

English

ISOTRIFOLIIN

Common Name

English

Classification Tree Code System Code

DSLD

3889 (Number of products:4)