Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C21H20O12 |
Molecular Weight | 464.3771 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 5 / 5 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
c1cc(c(cc1-c2c(c(=O)c3c(cc(cc3o2)O)O)O[C@@]4([H])[C@@]([H])([C@]([H])([C@@]([H])([C@@]([H])(CO)O)O4)O)O)O)O
InChI
InChIKey=OPJZLUXFQFQYAI-GNPVFZCLSA-N
InChI=1S/C21H20O12/c22-6-12(27)19-16(29)17(30)21(32-19)33-20-15(28)14-11(26)4-8(23)5-13(14)31-18(20)7-1-2-9(24)10(25)3-7/h1-5,12,16-17,19,21-27,29-30H,6H2/t12-,16-,17-,19-,21+/m1/s1
Molecular Formula | C21H20O12 |
Molecular Weight | 464.3771 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 5 / 5 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: GO:0016055 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25359775 |
|||
Target ID: CHEMBL1900 Sources: https://www.ncbi.nlm.nih.gov/pubmed/22261024 |
4.5 µM [IC50] | ||
Target ID: CHEMBL3108635 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24521209 |
2.0 µM [IC50] | ||
Target ID: CHEMBL2326 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26498393 |
3.8 nM [IC50] |
PubMed
Title | Date | PubMed |
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[HPLC investigation of antioxidant components in Solidago herba]. | 2004 |
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Glycosides from Grewia damine and Filicium decipiens. | 2004 Dec |
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Isolation of angiotensin converting enzyme (ACE) inhibitory flavonoids from Sedum sarmentosum. | 2004 Dec |
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[Studies on the chemical constituents of Knoxia corymbosa]. | 2004 Jun |
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[Studies on chemical constituents from Salvia roborowskii Maxim]. | 2005 Feb |
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[Applications of two-dimensional liquid chromatography coupled to mass spectrometry for the separation and identification of compounds in ginkgo biloba extracts]. | 2005 Jan |
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[Study on chemical constituents of Lagotis yunnanensis]. | 2005 Sep |
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[Studies on chemical constituents from flowers of Apocynum venetum]. | 2005 Sep |
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Quantitative determination of major active components in Ginkgo biloba dietary supplements by liquid chromatography/mass spectrometry. | 2006 |
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Inhibition of human cytochrome CYP 1 enzymes by flavonoids of St. John's wort. | 2006 Jan 16 |
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Constituents from the leaves of Phellodendron amurense and their antioxidant activity. | 2006 Sep |
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Development of an HPLC-PAD-MS assay for the identification and quantification of major phenolic edelweiss (Leontopodium alpium Cass.) constituents. | 2006 Sep-Oct |
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Simultaneous determination of seven flavonoids in Potentilla multifida by HPLC. | 2007 Apr |
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[Studies on antiproliferative effect of flavones compounds isolated from Yao herb medicines]. | 2007 Aug |
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An unusual C6-C6" linked flavonoid from Miconia cabucu (Melastomataceae). | 2007 Jul |
|
The anti-thrombotic active constituents from Centella asiatica. | 2007 May |
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Three new 3-benzylbenzofuran-2-one derivatives from Homalium brachybotrys (Flacourtiaceae/Salicaceae s. l.). | 2007 Nov |
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[Isolation and preparation of flavones from the leaves of Lindera aggregata using high speed counter-current chromatography]. | 2007 Sep |
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[Study on antioxidant activity of constituents from mulberry leaf]. | 2008 Apr |
|
[Studies on chemical constituents of Primula sikkmensis]. | 2008 Jan |
|
Quercetin 3-glucoside protects neuroblastoma (SH-SY5Y) cells in vitro against oxidative damage by inducing sterol regulatory element-binding protein-2-mediated cholesterol biosynthesis. | 2008 Jan 25 |
|
[Chemical constituents from Polygonum capitatum and their antioxidation activities in vitro]. | 2008 Jul |
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Soil quality effects on Chenopodium album flavonoid content and antioxidant potential. | 2008 Jul 9 |
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Determination of quercetin and its glucosides in onion by electrochemical methods. | 2008 Jun 9 |
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[Studies on chemical constituents of Arachniodes rhomboidea]. | 2008 Mar |
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Deconjugation and degradation of flavonol glycosides by pig cecal microbiota characterized by Fluorescence in situ hybridization (FISH). | 2008 Mar 26 |
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Camellia japonica suppresses immunoglobulin E-mediated allergic response by the inhibition of Syk kinase activation in mast cells. | 2008 May |
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Pharmacological basis for use of Pistacia integerrima leaves in hyperuricemia and gout. | 2008 May 22 |
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Determination of the relative contribution of quercetin and its glucosides to the antioxidant capacity of onion by cyclic voltammetry and spectrophotometric methods. | 2008 May 28 |
|
Taxodione, a DNA-binding compound from Taxodium distichum L. (Rich.). | 2008 May-Jun |
|
[Flavones from flowers of Paulownia fortunei]. | 2008 Nov |
|
Phytochemicals of apple peels: isolation, structure elucidation, and their antiproliferative and antioxidant activities. | 2008 Nov 12 |
|
Flavonoid glycosides isolated from Salicornia herbacea inhibit matrix metalloproteinase in HT1080 cells. | 2008 Oct |
|
Light filtering by epidermal flavonoids during the resistant response of cotton to Xanthomonas protects leaf tissue from light-dependent phytoalexin toxicity. | 2008 Sep |
|
Deep supercooling xylem parenchyma cells of katsura tree (Cercidiphyllum japonicum) contain flavonol glycosides exhibiting high anti-ice nucleation activity. | 2008 Sep |
|
Chemical composition of the stem bark and leaves of Ficus pandurata Hance. | 2009 |
|
[Chemical constituents from Neo-Taraxacum siphonathum]. | 2009 Apr |
|
[Chemical study on ethyl acetate soluble portion of Kadsura oblongifolia]. | 2009 Apr |
|
[Study on chemical constituents of Herba Cirsii]. | 2009 Jan |
|
[Flavonoid constituents from herbs of Sarcopyramis bodinieri var. delicata]. | 2009 Jan |
|
[Flavones from Helichrysi flos syn]. | 2009 Jun |
|
[Chemical constituents of Galium verum]. | 2009 Nov |
|
[Chemical constituents from leaves of Sterculia foetida]. | 2009 Oct |
|
Nondigestible saccharides suppress the bacterial degradation of quercetin aglycone in the large intestine and enhance the bioavailability of quercetin glucoside in rats. | 2009 Oct 28 |
|
Phenolic compounds in leaves of Alchornea triplinervia: anatomical localization, mutagenicity, and antibacterial activity. | 2010 Aug |
|
Antioxidant enzymatically modified isoquercitrin or melatonin supplementation reduces oxidative stress-mediated hepatocellular tumor promotion of oxfendazole in rats. | 2010 Feb |
|
Antioxidant enzymatically modified isoquercitrin suppresses the development of liver preneoplastic lesions in rats induced by beta-naphthoflavone. | 2010 Feb 9 |
|
Preparative isolation and purification of four flavonoids from the petals of Nelumbo nucifera by high-speed counter-current chromatography. | 2010 May-Jun |
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Screening medicinal plants for the detection of novel antimalarial products applying the inhibition of β-hematin formation. | 2011 Dec 15 |
|
Effect of enzymatically modified isoquercitrin on preneoplastic liver cell lesions induced by thioacetamide promotion in a two-stage hepatocarcinogenesis model using rats. | 2013 Mar 8 |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Jun 26 06:28:44 UTC 2021
by
admin
on
Sat Jun 26 06:28:44 UTC 2021
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Record UNII |
0YX10VRV6J
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Record Status |
Validated (UNII)
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Record Version |
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-
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Classification Tree | Code System | Code | ||
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DSLD |
3889 (Number of products:4)
Created by
admin on Sat Jun 26 06:28:44 UTC 2021 , Edited by admin on Sat Jun 26 06:28:44 UTC 2021
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NCI_THESAURUS |
C270
Created by
admin on Sat Jun 26 06:28:44 UTC 2021 , Edited by admin on Sat Jun 26 06:28:44 UTC 2021
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Code System | Code | Type | Description | ||
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C016527
Created by
admin on Sat Jun 26 06:28:44 UTC 2021 , Edited by admin on Sat Jun 26 06:28:44 UTC 2021
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PRIMARY | |||
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Isoquercitrin
Created by
admin on Sat Jun 26 06:28:44 UTC 2021 , Edited by admin on Sat Jun 26 06:28:44 UTC 2021
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PRIMARY | |||
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21637-25-2
Created by
admin on Sat Jun 26 06:28:44 UTC 2021 , Edited by admin on Sat Jun 26 06:28:44 UTC 2021
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PRIMARY | |||
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C99879
Created by
admin on Sat Jun 26 06:28:44 UTC 2021 , Edited by admin on Sat Jun 26 06:28:44 UTC 2021
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PRIMARY | |||
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5484006
Created by
admin on Sat Jun 26 06:28:44 UTC 2021 , Edited by admin on Sat Jun 26 06:28:44 UTC 2021
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PRIMARY | |||
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0YX10VRV6J
Created by
admin on Sat Jun 26 06:28:44 UTC 2021 , Edited by admin on Sat Jun 26 06:28:44 UTC 2021
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PRIMARY | |||
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244-488-5
Created by
admin on Sat Jun 26 06:28:44 UTC 2021 , Edited by admin on Sat Jun 26 06:28:44 UTC 2021
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PRIMARY |
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PARENT -> IMPURITY |
NMT 2%
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