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Details

Stereochemistry ABSOLUTE
Molecular Formula C21H20O12
Molecular Weight 464.3763
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ISOQUERCITRIN

SMILES

[H][C@@]1(O[C@@H](OC2=C(OC3=C(C2=O)C(O)=CC(O)=C3)C4=CC=C(O)C(O)=C4)[C@H](O)[C@H]1O)[C@H](O)CO

InChI

InChIKey=OPJZLUXFQFQYAI-GNPVFZCLSA-N
InChI=1S/C21H20O12/c22-6-12(27)19-16(29)17(30)21(32-19)33-20-15(28)14-11(26)4-8(23)5-13(14)31-18(20)7-1-2-9(24)10(25)3-7/h1-5,12,16-17,19,21-27,29-30H,6H2/t12-,16-,17-,19-,21+/m1/s1

HIDE SMILES / InChI

Molecular Formula C21H20O12
Molecular Weight 464.3763
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 5 / 5
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
4.5 µM [IC50]
2.0 µM [IC50]
3.8 nM [IC50]
PubMed

PubMed

TitleDatePubMed
Inhibition of HIV infection by flavanoids.
1993 Oct
Inhibitory effects of Egyptian folk medicines on human immunodeficiency virus (HIV) reverse transcriptase.
1995 Apr
Inhibitory activity of flavonoids and tannins against HIV-1 protease.
2000 Sep
Isolation of angiotensin converting enzyme (ACE) inhibitory flavonoids from Sedum sarmentosum.
2004 Dec
[Study on chemical constituents of Lagotis yunnanensis].
2005 Sep
Quantitative determination of major active components in Ginkgo biloba dietary supplements by liquid chromatography/mass spectrometry.
2006
Simultaneous determination of seven flavonoids in Potentilla multifida by HPLC.
2007 Apr
An unusual C6-C6" linked flavonoid from Miconia cabucu (Melastomataceae).
2007 Jul
The anti-thrombotic active constituents from Centella asiatica.
2007 May
Three new 3-benzylbenzofuran-2-one derivatives from Homalium brachybotrys (Flacourtiaceae/Salicaceae s. l.).
2007 Nov
[Studies on chemical constituents of Primula sikkmensis].
2008 Jan
[Studies on chemical constituents of Arachniodes rhomboidea].
2008 Mar
[Flavones from flowers of Paulownia fortunei].
2008 Nov
Phytochemicals of apple peels: isolation, structure elucidation, and their antiproliferative and antioxidant activities.
2008 Nov 12
[Chemical constituents from Neo-Taraxacum siphonathum].
2009 Apr
[Chemical constituents in Buddleja albiflora].
2009 Dec
[Flavonoid constituents from herbs of Sarcopyramis bodinieri var. delicata].
2009 Jan
[Chemical constituents of Galium verum].
2009 Nov
Phenolic compounds in leaves of Alchornea triplinervia: anatomical localization, mutagenicity, and antibacterial activity.
2010 Aug
Antioxidant enzymatically modified isoquercitrin or melatonin supplementation reduces oxidative stress-mediated hepatocellular tumor promotion of oxfendazole in rats.
2010 Feb
[Flavonoids of Lysimachia paridiformis var. stenophylla].
2010 Jul
[Flavonoids and phenolic acid derivatives from flos farfarae].
2010 May
Preparative isolation and purification of four flavonoids from the petals of Nelumbo nucifera by high-speed counter-current chromatography.
2010 May-Jun
Concomitant apoptosis and regeneration of liver cells as a mechanism of liver-tumor promotion by β-naphthoflavone involving TNFα-signaling due to oxidative cellular stress in rats.
2011 Apr 28
Screening medicinal plants for the detection of novel antimalarial products applying the inhibition of β-hematin formation.
2011 Dec 15
Effect of enzymatically modified isoquercitrin on preneoplastic liver cell lesions induced by thioacetamide promotion in a two-stage hepatocarcinogenesis model using rats.
2013 Mar 8
Patents

Patents

Substance Class Chemical
Created
by admin
on Fri Dec 15 19:39:40 GMT 2023
Edited
by admin
on Fri Dec 15 19:39:40 GMT 2023
Record UNII
0YX10VRV6J
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ISOQUERCITRIN
INCI  
INCI  
Official Name English
QUERCETIN 3-O-.BETA.-D-GLUCOFURANOSIDE
Common Name English
FEMA NO. 4225
Code English
ISOQUERCITRIN [INCI]
Common Name English
FLAVONE, 3,3',4',5,7-PENTAHYDROXY-, 3-.BETA.-D-GLUCOFURANOSIDE
Common Name English
QUERCETIN 3-(.BETA.-D-GLUCOFURANOSIDE)
Common Name English
ISOTRIFOLIN
Common Name English
ISOQUERCITROSIDE
Common Name English
ISOQUERCETIN ENZYMATICALLY MODIFIED [FHFI]
Common Name English
4H-1-BENZOPYRAN-4-ONE, 2-(3,4-DIHYDROXYPHENYL)-3-(.BETA.-D-GLUCOFURANOSYLOXY)-5,7-DIHYDROXY-
Common Name English
ISOTRIFOLIIN
Common Name English
Classification Tree Code System Code
DSLD 3889 (Number of products:4)
Created by admin on Fri Dec 15 19:39:40 GMT 2023 , Edited by admin on Fri Dec 15 19:39:40 GMT 2023
NCI_THESAURUS C270
Created by admin on Fri Dec 15 19:39:40 GMT 2023 , Edited by admin on Fri Dec 15 19:39:40 GMT 2023
Code System Code Type Description
MESH
C016527
Created by admin on Fri Dec 15 19:39:40 GMT 2023 , Edited by admin on Fri Dec 15 19:39:40 GMT 2023
PRIMARY
CHEBI
28299
Created by admin on Fri Dec 15 19:39:40 GMT 2023 , Edited by admin on Fri Dec 15 19:39:40 GMT 2023
PRIMARY
WIKIPEDIA
Isoquercitrin
Created by admin on Fri Dec 15 19:39:40 GMT 2023 , Edited by admin on Fri Dec 15 19:39:40 GMT 2023
PRIMARY
EPA CompTox
DTXSID80904976
Created by admin on Fri Dec 15 19:39:40 GMT 2023 , Edited by admin on Fri Dec 15 19:39:40 GMT 2023
PRIMARY
CAS
21637-25-2
Created by admin on Fri Dec 15 19:39:40 GMT 2023 , Edited by admin on Fri Dec 15 19:39:40 GMT 2023
PRIMARY
NCI_THESAURUS
C99879
Created by admin on Fri Dec 15 19:39:40 GMT 2023 , Edited by admin on Fri Dec 15 19:39:40 GMT 2023
PRIMARY
PUBCHEM
5484006
Created by admin on Fri Dec 15 19:39:40 GMT 2023 , Edited by admin on Fri Dec 15 19:39:40 GMT 2023
PRIMARY
FDA UNII
0YX10VRV6J
Created by admin on Fri Dec 15 19:39:40 GMT 2023 , Edited by admin on Fri Dec 15 19:39:40 GMT 2023
PRIMARY
ECHA (EC/EINECS)
244-488-5
Created by admin on Fri Dec 15 19:39:40 GMT 2023 , Edited by admin on Fri Dec 15 19:39:40 GMT 2023
PRIMARY
CHEBI
68352
Created by admin on Fri Dec 15 19:39:40 GMT 2023 , Edited by admin on Fri Dec 15 19:39:40 GMT 2023
PRIMARY
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