U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula 2Na.O4S.10H2O
Molecular Weight 322.195
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM SULFATE

SMILES

O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].[O-]S([O-])(=O)=O

InChI

InChIKey=RSIJVJUOQBWMIM-UHFFFAOYSA-L
InChI=1S/2Na.H2O4S.10H2O/c;;1-5(2,3)4;;;;;;;;;;/h;;(H2,1,2,3,4);10*1H2/q2*+1;;;;;;;;;;;/p-2

HIDE SMILES / InChI

Molecular Formula H2O4S
Molecular Weight 98.078
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Sodium sulfate anhydrous is an electrolyte replenisher and is used in isosmotic solutions so that administration does not disturb normal electrolyte balance and does not lead to absorption or excretion of water and ions. It is indicated for bowel cleansing prior to colonoscopy or barium enema X-ray examination. Sodium Sulfate, Potassium Sulfate and Magnesium Sulfate Oral Solution is indicated for cleansing of the colon as a preparation for colonoscopy in adults.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
GOLYTELY

Approved Use

GoLYTELY is indicated for bowel cleansing prior to colonoscopy and barium enema X-ray examination in adults.

Launch Date

1984
PubMed

PubMed

TitleDatePubMed
Different populations of progesterone receptor-steroid complexes in binding to specific DNA sequences: effects of salts on kinetics and specificity.
1998 Nov
Respiratory tract responses to repeated inhalation of an oxidant and acid gas-particle air pollutant mixture.
2001 Jun
Peroxides and macrophages in the toxicity of fine particulate matter in rats.
2003 Dec
Chemicals inducing acute irritant contact dermatitis mobilize intracellular calcium in human keratinocytes.
2013 Feb
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:15:54 GMT 2023
Edited
by admin
on Fri Dec 15 16:15:54 GMT 2023
Record UNII
0YPR65R21J
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM SULFATE
FCC   GREEN BOOK   II   INCI   MART.   ORANGE BOOK   USP   VANDF   WHO-IP  
INCI  
Official Name English
GLAUBER'S SALT
Common Name English
INS NO.514(I)
Code English
SODIUM SULFATE DECAHYDRATE [EP MONOGRAPH]
Common Name English
SODIUM SULFATE [VANDF]
Common Name English
SODIUM SULFATE COMPONENT OF SUPREP BOWEL PREP KIT
Common Name English
NATRUM SULPHURICUM [HPUS]
Common Name English
SODIUM SULFATE [ORANGE BOOK]
Common Name English
DISODIUM SULPHATE DECAHYDRATE
Systematic Name English
SODIUM SULFATE DECAHYDRATE
EP   II   WHO-DD  
Systematic Name English
SUPREP BOWEL PREP KIT COMPONENT SODIUM SULFATE
Common Name English
SULFURIC ACID DISODIUM SALT, DECAHYDRATE
Common Name English
NATRII SULFAS
CHP   WHO-IP LATIN  
Common Name English
Disodium sulfate decahydrate
Systematic Name English
NATRUM SULPHURICUM
HPUS  
Common Name English
SODIUM SULFATE HYDRATE [JAN]
Common Name English
MANGXIAO
Common Name English
MANG XIAO
Common Name English
SODIUM SULPHATE
Systematic Name English
NATRII SULFAS [WHO-IP LATIN]
Common Name English
Sodium sulfate decahydrate [WHO-DD]
Common Name English
Mirabilite [WHO-DD]
Common Name English
SODIUM SULFATE [FCC]
Common Name English
SODIUM SULFATE [GREEN BOOK]
Common Name English
SODIUM SULFATE [INCI]
Common Name English
SODIUM SULFATE [USP MONOGRAPH]
Common Name English
SODIUM SULFATE [II]
Common Name English
INS-514(I)
Code English
E-514(I)
Code English
SODIUM SULPHATE DECAHYDRATE
Systematic Name English
SODIUM SULFATE [WHO-IP]
Common Name English
NATRII SULFAS [CHP]
Common Name English
BLI801 COMPONENT SODIUM SULFATE
Code English
SODIUM SULFATE DECAHYDRATE [II]
Common Name English
BLI-801 COMPONENT SODIUM SULFATE
Common Name English
SODIUM SULFATE [MART.]
Common Name English
MIRABILITE
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29730
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
FDA ORPHAN DRUG 616817
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
WHO-ATC A06AD13
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
JECFA EVALUATION INS-514(I)
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
DSLD 3059 (Number of products:27)
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
WHO-VATC QA12CA02
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
FDA ORPHAN DRUG 403513
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
CODEX ALIMENTARIUS (GSFA) INS-514(I)
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
EPA PESTICIDE CODE 5604
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
WHO-ATC A12CA02
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
CFR 21 CFR 186.1797
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
WHO-VATC QA06AD13
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
FDA ORPHAN DRUG 379212
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
Code System Code Type Description
DRUG CENTRAL
4212
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
SODIUM SULFATE
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
PRIMARY Description: Colourless crystals or a white powder; odourless. Solubility: Freely soluble in water; practically insoluble in ethanol (~750 g/l) TS. Category: Laxative. Storage: Sodium sulfate should be kept in a well-closed container. Additional information: Sodium sulfate partially dissolves in its own water of crystallization at about 33?C. Definition: Sodium sulfate contains not less than 99.0% and not more than 100.5% of Na2SO4, calculated with reference to the dried substance.
DAILYMED
0YPR65R21J
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
PRIMARY
ChEMBL
CHEMBL233406
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
PRIMARY
SMS_ID
100000079578
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
PRIMARY
NCI_THESAURUS
C47727
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
PRIMARY
EVMPD
SUB20969
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
PRIMARY
PUBCHEM
62649
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
PRIMARY
MESH
C012036
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
PRIMARY
DRUG BANK
DB09472
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
PRIMARY
CHEBI
32149
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
PRIMARY
EPA CompTox
DTXSID80228003
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
PRIMARY
CHEBI
32586
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
PRIMARY
FDA UNII
0YPR65R21J
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
PRIMARY
RXCUI
36721
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
PRIMARY RxNorm
WIKIPEDIA
SODIUM SULFATE
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
PRIMARY
EVMPD
SUB12314MIG
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
PRIMARY
CAS
7727-73-3
Created by admin on Fri Dec 15 16:15:54 GMT 2023 , Edited by admin on Fri Dec 15 16:15:54 GMT 2023
PRIMARY
Related Record Type Details
ANHYDROUS->SOLVATE
Related Record Type Details
ACTIVE MOIETY