MEZAGITAMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 14:42:24 GMT 2023` Edited by `admin` on `Sat Dec 16 14:42:24 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	0XMR8L9LOL
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MEZAGITAMAB

Official Name

English

TAK079

Code

English

mezagitamab [INN]

Common Name

English

Mezagitamab [WHO-DD]

Common Name

English

TAK-079

Code

English

MEZAGITAMAB [USAN]

Common Name

English

IMMUNOGLOBULIN G1-LAMBDA, ANTI-(HOMO SAPIENS ADP-RIBOSYL CYCLASE/CYCLIC ADP-RIBOSE HYDROLASE 1 (2'-PHOSPHO-ADP-RIBOSYL CYCLASE, ANTIGENE CD38))HUMANIZED MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN HUMANIZED(1-453) (HOMO SAPIENS VH (IGHV3-23*01 (89%) (IGHD)-I

Common Name

English

ANTI-CD38 MONOCLONAL ANTIBODY TAK-079

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN CD38 ANTIGEN) (HUMAN MONOCLONAL AB79 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL AB79 .LAMBDA.-CHAIN, DIMER

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

667418

Created by admin on Sat Dec 16 14:42:24 GMT 2023 , Edited by admin on Sat Dec 16 14:42:24 GMT 2023

FDA ORPHAN DRUG

905822

Created by admin on Sat Dec 16 14:42:24 GMT 2023 , Edited by admin on Sat Dec 16 14:42:24 GMT 2023

Code System Code Type Description

USAN

HI-208

Created by admin on Sat Dec 16 14:42:24 GMT 2023 , Edited by admin on Sat Dec 16 14:42:24 GMT 2023

PRIMARY

NCI_THESAURUS

C148078

Created by admin on Sat Dec 16 14:42:24 GMT 2023 , Edited by admin on Sat Dec 16 14:42:24 GMT 2023

PRIMARY

CAS

2227490-52-8

Created by admin on Sat Dec 16 14:42:24 GMT 2023 , Edited by admin on Sat Dec 16 14:42:24 GMT 2023

PRIMARY

FDA UNII

0XMR8L9LOL

Created by admin on Sat Dec 16 14:42:24 GMT 2023 , Edited by admin on Sat Dec 16 14:42:24 GMT 2023

PRIMARY

INN

11159

Created by admin on Sat Dec 16 14:42:24 GMT 2023 , Edited by admin on Sat Dec 16 14:42:24 GMT 2023

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_150	2_206
2_226	4_215
2_267	2_327
1_150	1_206
2_373	2_431
3_22	3_89
3_138	3_197
4_22	4_89
4_138	4_197
1_226	3_215
1_232	2_232
1_235	2_235
1_267	1_327
1_373	1_431

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_303
N	2_303

Related Record Type Details


					6CC4WO1AUN

PLATELET GLYCOPROTEIN 4

TARGET -> INHIBITOR

Comments:

depletes human tumor cells expressing CD38 by antibody-dependent cellular cytotoxicity (ADCC) and complement dependent cytotoxicity (CDC).


					JMN849I3XV

ADP-RIBOSYL CYCLASE/CYCLIC ADP-RIBOSE HYDROLASE 1

TARGET -> INHIBITOR

Comments:

depletes human tumor cells expressing CD38 by antibody-dependent cellular cytotoxicity (ADCC) and complement dependent cytotoxicity (CDC).

Related Record Type Details


					0XMR8L9LOL

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL