SORBITAN SESQUIOLEATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	3C18H34O2.2C6H14O6
Molecular Weight	1211.7276
Optical Activity	UNSPECIFIED
Defined Stereocenters	8 / 8
E/Z Centers	3
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O

InChI

InChIKey=CUNWUEBNSZSNRX-RKGWDQTMSA-N

InChI=1S/3C18H34O2.2C6H14O6/c3*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;2*7-1-3(9)5(11)6(12)4(10)2-8/h3*9-10H,2-8,11-17H2,1H3,(H,19,20);2*3-12H,1-2H2/b3*10-9-;;/t;;;2*3-,4+,5-,6-/m...11/s1

HIDE SMILES / InChI

Molecular Formula	C18H34O2
Molecular Weight	282.4614
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Molecular Formula	C6H14O6
Molecular Weight	182.1718
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: http://www.webmd.com/drugs/2/drug-64292/sorbitan-sesquioleate-topical/details | https://www.truthinaging.com/ingredients/sorbitan-sesquioleate

A sorbitol derivative emulsifier used in many topical agents. Sorbitan Sesquioleate is used in a variety of products including skin care products, skin cleansing products, moisturizers, eye makeup and other makeup, primarily as an emollient. It is added to formulas as a skin soother and moisturizer and is derived from sorbitol, a humectant. Sorbitol sesquioleate (SSO) have recently been implicated in allergic dermatitis.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Dermatoses 23 Sources: http://www.webmd.com/drugs/2/drug-64292/sorbitan-sesquioleate-topical/details	Inactive ingredient		Approved 8429	Clobetasol propionate ointment Approved Use Clobetasol propionate cream and ointment are super-high potency corticosteroid formulations indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses. Treatment beyond 2 consecutive weeks is not recommended, and the total dosage should not exceed 50 g per week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis. Use in children under 12 years of age is not recommended. Launch Date 1996

PubMed

Title	Date	PubMed
Fabrication and in vivo evaluation of highly pH-responsive acrylic microparticles for targeted gastrointestinal delivery.	2009 Jun 28	19491017

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 20:09:20 GMT 2023` Edited by `admin` on `Sat Dec 16 20:09:20 GMT 2023`
Record UNII	0W8RRI5W5A
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SORBITAN SESQUIOLEATE

Official Name

English

SORBITAN SESQUIOLEATE [USAN]

Common Name

English

SORBITAN SESQUIOLEATE [VANDF]

Common Name

English

SORBITAN SESQUIOLEATE [INCI]

Common Name

English

SORBITAN SESQUIOLEATE [EP MONOGRAPH]

Common Name

English

SORBITAN SESQUIOLEATE [MART.]

Common Name

English

SORBITAN SESQUIOLEATE [II]

Common Name

English

SORBITAN SESQUIOLEATE [JAN]

Common Name

English

SORBITAN SESQUIOLEATE [EP IMPURITY]

Common Name

English

Sorbitan sesquioleate [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C83486