DEFOSFAMIDE

Possibly Marketed Outside US

Details

Stereochemistry	RACEMIC
Molecular Formula	C9H20Cl3N2O3P
Molecular Weight	341.599
Optical Activity	( + / - )
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OCCCNP(=O)(OCCCl)N(CCCl)CCCl

InChI

InChIKey=FQWNGSKQHPNIQG-UHFFFAOYSA-N

InChI=1S/C9H20Cl3N2O3P/c10-2-6-14(7-3-11)18(16,17-9-4-12)13-5-1-8-15/h15H,1-9H2,(H,13,16)

HIDE SMILES / InChI

Molecular Formula	C9H20Cl3N2O3P
Molecular Weight	341.599
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13981675 | http://www.druglead.com/cds/Defosfamide.html | (1973) Cancer Chemotherapy Abstracts, v. 14, retrieved from: https://books.google.ru/books?id=Gr4TAQAAMAAJ

Defosfamide (Mitarson) was developed as antineoplastic agent. Mitarson and radioactive gold were used in some patients with poor results. The most serious complication resulting from therapy was hemorrhagic cystitis.

Approval Year

Patents

Sample Use Guides

In Vivo Use Guide

Dosу - 100 mg

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:24:45 GMT 2025` Edited by `admin` on `Mon Mar 31 18:24:45 GMT 2025`
Record UNII	0W33021S30
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-40627

Preferred Name

English

DEFOSFAMIDE

Official Name

English

Defosfamide [WHO-DD]

Common Name

English

defosfamide [INN]

Common Name

English

DEFOSFAMIDE [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C697