STEPHOLIDINE

[H][C@@]12CC3=CC=C(O)C(OC)=C3CN1CCC4=CC(OC)=C(O)C=C24

InChIKey=JKPISQIIWUONPB-HNNXBMFYSA-N

InChI=1S/C19H21NO4/c1-23-18-8-12-5-6-20-10-14-11(3-4-16(21)19(14)24-2)7-15(20)13(12)9-17(18)22/h3-4,8-9,15,21-22H,5-7,10H2,1-2H3/t15-/m0/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Targets

Primary Target	Pharmacology	Potency
Dopamine D2 receptor 297 Target ID: CHEMBL217 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25231919	Antagonist 2778	11.6 nM [Ki]
Dopamine D1 receptor 101 Target ID: CHEMBL2056 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25231919	Antagonist 2778	5.1 nM [Ki]
Dopamine D3 receptor 91 Target ID: CHEMBL234 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25231919	Antagonist 2778	23.4 nM [Ki]
Dopamine D4 receptor 71 Target ID: CHEMBL219 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25231919	Antagonist 2778	1453.0 nM [Ki]
Dopamine D5 receptor 12 Target ID: CHEMBL1850 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25231919	Antagonist 2778	5.8 nM [Ki]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 09:39:57 GMT 2023` Edited by `admin` on `Sat Dec 16 09:39:57 GMT 2023`
Record UNII	0UPX3E69W8
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

STEPHOLIDINE

Common Name

English

(13AS)-5,8,13,13A-TETRAHYDRO-3,9-DIMETHOXY-6H-DIBENZO(A,G)QUINOLIZINE-2,10-DIOL

Systematic Name

English

Stepholidine [WHO-DD]

Common Name

English

STEPHOLIDINE, (-)-

Common Name

English

6H-DIBENZO(A,G)QUINOLIZINE-2,10-DIOL, 5,8,13,13A-TETRAHYDRO-3,9-DIMETHOXY-, (13AS)-

Systematic Name

English

(-)-STEPHOLIDINE

Common Name

English

L-STEPHOLIDINE

Common Name

English

13A.ALPHA.-BERBINE-2,10-DIOL, 3,9-DIMETHOXY-

Systematic Name

English

Code System Code Type Description

WIKIPEDIA

Stepholidine