4,4',4''-(4-PROPYL-(1H)-PYRAZOLE-1,3,5-TRIYL)TRISPHENOL

CCCC1=C(N(N=C1C2=CC=C(O)C=C2)C3=CC=C(O)C=C3)C4=CC=C(O)C=C4

InChIKey=IOTXSIGGFRQYKW-UHFFFAOYSA-N

InChI=1S/C24H22N2O3/c1-2-3-22-23(16-4-10-19(27)11-5-16)25-26(18-8-14-21(29)15-9-18)24(22)17-6-12-20(28)13-7-17/h4-15,27-29H,2-3H2,1H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
Estrogen receptor alpha 134 Target ID: CHEMBL206 Sources: https://www.ncbi.nlm.nih.gov/pubmed/12399409 \| https://www.ncbi.nlm.nih.gov/pubmed/11150164 \| https://www.ncbi.nlm.nih.gov/pubmed/11014206	Agonist 2752		200.0 pM [EC50]

PubMed

Title	Date	PubMed
Characterization of the biological roles of the estrogen receptors, ERalpha and ERbeta, in estrogen target tissues in vivo through the use of an ERalpha-selective ligand.	2002-11	12399409
Pyrazole ligands: structure-affinity/activity relationships and estrogen receptor-alpha-selective agonists.	2000-12-28	11150164
Conformational changes and coactivator recruitment by novel ligands for estrogen receptor-alpha and estrogen receptor-beta: correlations with biological character and distinct differences among SRC coactivator family members.	2000-10	11014206

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:17:51 GMT 2025` Edited by `admin` on `Mon Mar 31 22:17:51 GMT 2025`
Record UNII	0T83Y6JZPF
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

4,4',4''-(4-PROPYL-(1H)-PYRAZOLE-1,3,5-TRIYL)TRISPHENOL

Systematic Name

English

PPT

Preferred Name

English

PHENOL, 4,4',4''-(4-PROPYL-1H-PYRAZOLE-1,3,5-TRIYL)TRIS-

Systematic Name

English

PROPYL PYRAZOLE TRIOL

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID9040392