U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Thu Jul 06 21:12:04 UTC 2023
Edited
by admin
on Thu Jul 06 21:12:04 UTC 2023
Protein Type VIRAL NON-STRUCTURAL PROTEIN
Protein Sub Type
Sequence Origin VIRAL
Sequence Type COMPLETE
Record UNII
0T3KCZ2856
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
3C-LIKE PROTEINASE (SARS-COV-2)
Common Name English
3C-LIKE CYSTEINE PROTEINASE (SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2)
Common Name English
3CL-PRO (SARS-COV-2, WUHAN-HU-1)
Common Name English
CoV-2 3CLpro
Common Name English
NSP5 (SARS-COV-2, WUHAN-HU-1)
Common Name English
NON-STRUCTURAL PROTEIN 5 (SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2)
Common Name English
3CLPRO (SARS-COV-2, WUHAN-HU-1)
Common Name English
Code System Code Type Description
FDA UNII
0T3KCZ2856
Created by admin on Thu Jul 06 21:12:05 UTC 2023 , Edited by admin on Thu Jul 06 21:12:05 UTC 2023
PRIMARY
Related Record Type Details
INHIBITOR -> TARGET
IC50
INHIBITOR -> TARGET
Protease activity inhibited via a reversible covalent mechanism involving reaction of the cyano group with the catalytic Cys145 residue
Ki
INHIBITOR -> TARGET
Ki
WEAK INHIBITOR->TARGET
INHIBITOR -> TARGET
Ki
PARENT->CLEAVED PROTEIN
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL