GRESONITAMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 05:02:48 GMT 2025` Edited by `admin` on `Wed Apr 02 05:02:48 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	0SIB91V6TP
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

GRESONITAMAB

Official Name

English

AMG 910 [WHO-DD]

Preferred Name

English

IMMUNOGLOBULIN, BISPECIFIC, ANTI-(HUMAN CLAUDIN 18.2) (HUMAN MONOCLONAL HWZV_KLA_L SINGLE-CHAIN VARIABLE FRAGMENT VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN CD3 ANTIGEN .EPSILON.-CHAIN) (HU

Common Name

English

gresonitamab [INN]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

752720

Created by admin on Wed Apr 02 05:02:48 GMT 2025 , Edited by admin on Wed Apr 02 05:02:48 GMT 2025

Code System Code Type Description

INN

11798

Created by admin on Wed Apr 02 05:02:48 GMT 2025 , Edited by admin on Wed Apr 02 05:02:48 GMT 2025

PRIMARY

NCI_THESAURUS

C184829

Created by admin on Wed Apr 02 05:02:48 GMT 2025 , Edited by admin on Wed Apr 02 05:02:48 GMT 2025

PRIMARY

FDA UNII

0SIB91V6TP

Created by admin on Wed Apr 02 05:02:48 GMT 2025 , Edited by admin on Wed Apr 02 05:02:48 GMT 2025

PRIMARY

CAS

2413817-97-5

Created by admin on Wed Apr 02 05:02:48 GMT 2025 , Edited by admin on Wed Apr 02 05:02:48 GMT 2025

PRIMARY

SMS_ID

300000017532

Created by admin on Wed Apr 02 05:02:48 GMT 2025 , Edited by admin on Wed Apr 02 05:02:48 GMT 2025

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From	To
1_22	1_96
1_44	1_240
1_163	1_228
1_275	1_351
1_415	1_483
1_512	1_769
1_515	1_772
1_547	1_607
1_578	1_588
1_653	1_711
1_804	1_864
1_835	1_845
1_910	1_968

Related Record Type Details


					1U72JD9DDZ

T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN

TARGET -> ACTIVATOR

Related Record Type Details


					0SIB91V6TP

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_990]	C-TERMINUS			LYSINE	K3Z4F929H6
AMINO_ACID_SUBSTITUTION	[1_1]	N-TERMINUS			PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL