Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H5Cl5 |
| Molecular Weight | 326.433 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC1=C(Cl)C=C(C=C1)C2=C(Cl)C(Cl)=C(Cl)C=C2
InChI
InChIKey=WIDHRBRBACOVOY-UHFFFAOYSA-N
InChI=1S/C12H5Cl5/c13-8-3-1-6(5-10(8)15)7-2-4-9(14)12(17)11(7)16/h1-5H
| Molecular Formula | C12H5Cl5 |
| Molecular Weight | 326.433 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Genome-wide association study of plasma levels of polychlorinated biphenyls disclose an association with the CYP2B6 gene in a population-based sample. | 2015-07 |
|
| Consensus toxicity factors for polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls combining in silico models and extensive in vitro screening of AhR-mediated effects in human and rodent cells. | 2015-04-20 |
|
| Functionality of aryl hydrocarbon receptors (AhR1 and AhR2) of white sturgeon (Acipenser transmontanus) and implications for the risk assessment of dioxin-like compounds. | 2014-07-15 |
|
| Cytochrome P4501A induction in avian hepatocyte cultures exposed to polychlorinated biphenyls: comparisons with AHR1-mediated reporter gene activity and in ovo toxicity. | 2013-01-01 |
|
| In utero and lactational exposure to PCBs in mice: adult offspring show altered learning and memory depending on Cyp1a2 and Ahr genotypes. | 2011-09 |
|
| In utero and lactational exposure to a complex mixture of polychlorinated biphenyls: toxicity in pups dependent on the Cyp1a2 and Ahr genotypes. | 2011-01 |
|
| Polychlorinated biphenyls, lead, and mercury are associated with liver disease in American adults: NHANES 2003-2004. | 2010-12 |
|
| Highly purified hexachlorobenzene induces cytochrome P4501A in primary cultures of chicken embryo hepatocytes. | 2010-11-01 |
|
| Generalized concentration addition predicts joint effects of aryl hydrocarbon receptor agonists with partial agonists and competitive antagonists. | 2010-05 |
|
| Transactivation potencies of Baikal seal constitutive active/androstane receptor by persistent organic pollutants and brominated flame retardants. | 2009-08-15 |
|
| Prevalence of metabolic syndrome associated with body burden levels of dioxin and related compounds among Japan's general population. | 2009-04 |
|
| Pharmacologic profiling of human and rat cytochrome P450 1A1 and 1A2 induction and competition. | 2008-12 |
|
| Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism. | 2008-04 |
|
| Relative potency based on hepatic enzyme induction predicts immunosuppressive effects of a mixture of PCDDS/PCDFS and PCBS. | 2008-03-15 |
|
| Polychlorinated biphenyls 105 and 118 form thyroid hormone receptor agonists after cytochrome P4501A1 activation in rat pituitary GH3 cells. | 2007-11 |
|
| Fungal bioconversion of toxic polychlorinated biphenyls by white-rot fungus, Phlebia brevispora. | 2006-12 |
|
| Determination of in vitro relative potency (REP) values for mono-ortho polychlorinated biphenyls after purification with active charcoal. | 2006-09-10 |
|
| Cytochrome P450 1A4 and 1A5 in common cormorant (Phalacrocorax carbo): evolutionary relationships and functional implications associated with dioxin and related compounds. | 2006-08 |
|
| Comparison of hepatic and extra hepatic induction of cytochrome P4501A by graded doses of aryl hydrocarbon receptor agonists in Atlantic tomcod from two populations. | 2006-03-10 |
|
| Inhibition of human and rat CYP1A2 by TCDD and dioxin-like chemicals. | 2005-04 |
|
| Suppression of aromatase activity in vitro by PCBs 28 and 105 and Aroclor 1221. | 2004-08-30 |
|
| Brominated dioxin-like compounds: in vitro assessment in comparison to classical dioxin-like compounds and other polyaromatic compounds. | 2003-09 |
|
| [Metabolism of 2,3,3',4,4'-pentachlorobiphenyl in hamsters]. | 2003-05 |
|
| Retinoid metabolism (LRAT, REH) in the yolk-sac membrane of Japanese quail eggs and effects of mono-ortho-PCBs. | 2003-01 |
|
| Placental transfer of a hydroxylated polychlorinated biphenyl and effects on fetal and maternal thyroid hormone homeostasis in the rat. | 2002-08 |
|
| Effects of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) on thyroid hormone and vitamin A levels in rats and mice. | 2001-06 |
|
| Dose-response relationships for induction of CYP1A1 and CYP1A2 enzyme activity in liver, lung, and skin in female mice following subchronic exposure to polychlorinated biphenyls. | 2000-09-15 |
|
| Induction of aberrant mitosis with PCBs: particular efficiency of 2, 3,3',4,4'-pentachlorobiphenyl and synergism with triphenyltin. | 2000-01 |
|
| Transactivation activity of human, zebrafish, and rainbow trout aryl hydrocarbon receptors expressed in COS-7 cells: greater insight into species differences in toxic potency of polychlorinated dibenzo-p-dioxin, dibenzofuran, and biphenyl congeners. | 1999-08-15 |
|
| Tissue distribution and effects on hepatic xenobiotic metabolising enzymes of 2,3,3',4,4'-pentachlorobiphenyl (PCB-105) in COD (Gadus morhua) and rainbow trout (Oncorhynchus mykiss). | 1994 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:17:12 GMT 2025
by
admin
on
Mon Mar 31 21:17:12 GMT 2025
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| Record UNII |
0S596V3MLH
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| Record Status |
Validated (UNII)
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| Record Version |
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DTXSID8038306
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0S596V3MLH
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32598-14-4
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