Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C9H12FN3O |
| Molecular Weight | 197.2095 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC(=N)NCCC1=CC(O)=C(F)C=C1
InChI
InChIKey=DBVYMDMGVRXUPK-UHFFFAOYSA-N
InChI=1S/C9H12FN3O/c10-7-2-1-6(5-8(7)14)3-4-13-9(11)12/h1-2,5,14H,3-4H2,(H4,11,12,13)
| Molecular Formula | C9H12FN3O |
| Molecular Weight | 197.2095 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Fluorine-18 labeled phenethylguanidines are currently under development as radiotracers for quantifying regional cardiac sympathetic nerve density using PET imaging techniques. [(18)F]4F-MHPG is a cardiac sympathetic nerve imaging agent with kinetic properties favorable for quantifying regional nerve density with PET and tracer kinetic analysis. .
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| [18F]Fluoro-Hydroxyphenethylguanidines: Efficient Synthesis and Comparison of Two Structural Isomers as Radiotracers of Cardiac Sympathetic Innervation. | 2017-07-19 |
|
| 4-[18F]Fluoro-m-hydroxyphenethylguanidine: a radiopharmaceutical for quantifying regional cardiac sympathetic nerve density with positron emission tomography. | 2013-09-26 |
|
| Synthesis and bioevaluation of [(18)F]4-fluoro-m-hydroxyphenethylguanidine ([(18)F]4F-MHPG): a novel radiotracer for quantitative PET studies of cardiac sympathetic innervation. | 2013-03-15 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 20:58:14 GMT 2025
by
admin
on
Mon Mar 31 20:58:14 GMT 2025
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| Record UNII |
0Q1093LYI4
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| Record Status |
Validated (UNII)
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0Q1093LYI4
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889882-04-6
Created by
admin on Mon Mar 31 20:58:14 GMT 2025 , Edited by admin on Mon Mar 31 20:58:14 GMT 2025
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