U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Wed Apr 02 01:25:04 GMT 2025
Edited
by admin
on Wed Apr 02 01:25:04 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG2
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
0O39RGI33V
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
IMMUNOGLOBULIN G2, ANTI-(HUMAN CD40 ANTIGEN RECEPTOR) (HUMAN MONOCLONAL IMAB CD40 HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL IMAB CD40 LIGHT CHAIN, DIMER
Preferred Name English
SELICRELUMAB
INN  
USAN   INN  
Official Name English
selicrelumab [INN]
Common Name English
IMMUNOGLOBULIN G2-KAPPA, ANTI-(HOMO SAPIENS TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5 (CD40 ANTIGEN)HOMO SAPIENS MONOCLONAL ANTIBODY.GAMMA.2 HEAVY CHAIN (1-452) (HOMO SAPIENS VH (IGHV1-2*02 (98%) (IGHD)-IGHJ4*01) (8.8.19) (1-126) -HOMO SAPIENS
Systematic Name English
SELICRELUMAB [USAN]
Common Name English
CP-870,893
Code English
CD40 AGONIST MONOCLONAL ANTIBODY CP-870,893
Common Name English
CP 870,893 [WHO-DD]
Common Name English
CP-870893
Code English
HUMAN MOAB (IGG2) (CP-870,893) TO CD40 RECEPTOR
Common Name English
Selicrelumab [WHO-DD]
Common Name English
RG7876
Code English
CP 870,893
Code English
NG-350A expressed anti-CD40 antibody
Common Name English
RG-7876
Code English
RO-7009789
Code English
Classification Tree Code System Code
NCI_THESAURUS C129823
Created by admin on Wed Apr 02 01:25:04 GMT 2025 , Edited by admin on Wed Apr 02 01:25:04 GMT 2025
NCI_THESAURUS C20401
Created by admin on Wed Apr 02 01:25:04 GMT 2025 , Edited by admin on Wed Apr 02 01:25:04 GMT 2025
NCI_THESAURUS C133877
Created by admin on Wed Apr 02 01:25:04 GMT 2025 , Edited by admin on Wed Apr 02 01:25:04 GMT 2025
Code System Code Type Description
CHEMBL
CHEMBL2109477
Created by admin on Wed Apr 02 01:25:04 GMT 2025 , Edited by admin on Wed Apr 02 01:25:04 GMT 2025
PRIMARY
INN
10523
Created by admin on Wed Apr 02 01:25:04 GMT 2025 , Edited by admin on Wed Apr 02 01:25:04 GMT 2025
PRIMARY
SMS_ID
100000177752
Created by admin on Wed Apr 02 01:25:04 GMT 2025 , Edited by admin on Wed Apr 02 01:25:04 GMT 2025
PRIMARY
CAS
1109228-14-9
Created by admin on Wed Apr 02 01:25:04 GMT 2025 , Edited by admin on Wed Apr 02 01:25:04 GMT 2025
ALTERNATIVE
NCI_THESAURUS
C152323
Created by admin on Wed Apr 02 01:25:04 GMT 2025 , Edited by admin on Wed Apr 02 01:25:04 GMT 2025
NO STRUCTURE GIVEN
USAN
FG-74
Created by admin on Wed Apr 02 01:25:04 GMT 2025 , Edited by admin on Wed Apr 02 01:25:04 GMT 2025
PRIMARY
DRUG BANK
DB14958
Created by admin on Wed Apr 02 01:25:04 GMT 2025 , Edited by admin on Wed Apr 02 01:25:04 GMT 2025
PRIMARY
FDA UNII
0O39RGI33V
Created by admin on Wed Apr 02 01:25:04 GMT 2025 , Edited by admin on Wed Apr 02 01:25:04 GMT 2025
PRIMARY
CAS
1622140-49-1
Created by admin on Wed Apr 02 01:25:04 GMT 2025 , Edited by admin on Wed Apr 02 01:25:04 GMT 2025
PRIMARY
NCI_THESAURUS
C119740
Created by admin on Wed Apr 02 01:25:04 GMT 2025 , Edited by admin on Wed Apr 02 01:25:04 GMT 2025
PRIMARY
From To
2_140 4_214
2_105 2_110
1_229 2_229
1_228 2_228
1_105 1_110
1_22 1_96
1_153 1_209
1_266 1_326
1_372 1_430
2_22 2_96
2_153 2_209
2_266 2_326
2_372 2_430
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
1_140 3_214
1_232 2_232
1_235 2_235
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_302
N 2_302
Related Record Type Details
TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5
TARGET -> AGONIST
Related Record Type Details
SELICRELUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT(CALCULATED) CHEMICAL
NIH
NCATS
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