Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C21H25FN6O3 |
| Molecular Weight | 428.46 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]1(CCCO1)C2=C3NC(NC(=O)NCC)=NC3=CC(C4=CN=C(N=C4)C(C)(C)O)=C2F
InChI
InChIKey=BKUISYCLLXCBJV-CQSZACIVSA-N
InChI=1S/C21H25FN6O3/c1-4-23-20(29)28-19-26-13-8-12(11-9-24-18(25-10-11)21(2,3)30)16(22)15(17(13)27-19)14-6-5-7-31-14/h8-10,14,30H,4-7H2,1-3H3,(H3,23,26,27,28,29)/t14-/m1/s1
| Molecular Formula | C21H25FN6O3 |
| Molecular Weight | 428.46 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 15:13:55 GMT 2023
by
admin
on
Sat Dec 16 15:13:55 GMT 2023
|
| Record UNII |
0O34AIS1YE
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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| Code System | Code | Type | Description | ||
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300000039064
Created by
admin on Sat Dec 16 15:13:56 GMT 2023 , Edited by admin on Sat Dec 16 15:13:56 GMT 2023
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57524959
Created by
admin on Sat Dec 16 15:13:56 GMT 2023 , Edited by admin on Sat Dec 16 15:13:56 GMT 2023
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1384984-18-2
Created by
admin on Sat Dec 16 15:13:56 GMT 2023 , Edited by admin on Sat Dec 16 15:13:56 GMT 2023
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PRIMARY | |||
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0O34AIS1YE
Created by
admin on Sat Dec 16 15:13:56 GMT 2023 , Edited by admin on Sat Dec 16 15:13:56 GMT 2023
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PRIMARY |
| Related Record | Type | Details | ||
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TARGET ORGANISM->INHIBITOR |
SPR719 showed potent activity against MAC (MIC90, 2 mg/liter) and M. kansasii (MIC90, 0.125 mg/liter) and modest activity against M. abscessus (MIC90, 8 mg/liter); its activity is bacteriostatic and concentration-dependent.
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TARGET -> INHIBITOR |
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TARGET ORGANISM->INHIBITOR |
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TARGET ORGANISM->INHIBITOR |
SPR719 showed potent activity against MAC (MIC90, 2 mg/liter) and M. kansasii (MIC90, 0.125 mg/liter) and modest activity against M. abscessus (MIC90, 8 mg/liter); its activity is bacteriostatic and concentration-dependent.
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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PRODRUG -> METABOLITE ACTIVE |
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| Related Record | Type | Details | ||
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ACTIVE MOIETY |
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