Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H6Br4O |
| Molecular Weight | 485.791 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
BrC1=CC(Br)=C(OC2=C(Br)C=C(Br)C=C2)C=C1
InChI
InChIKey=XYBSIYMGXVUVGY-UHFFFAOYSA-N
InChI=1S/C12H6Br4O/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6H
| Molecular Formula | C12H6Br4O |
| Molecular Weight | 485.791 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Cytogenotoxicity induced by PBDE-47 combined with PCB153 treatment in SH-SY5Y cells. | 2010-12 |
|
| Vibrational spectroscopic investigation and DFT studies on 2,2',4,4'-tetrabromodiphenyl ether. | 2010-10-15 |
|
| Polybrominated diphenyl ethers and arylhydrocarbon receptor agonists: Different toxicity and target gene expression. | 2010-10-05 |
|
| Metabolism of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) in chickens. | 2010-08-11 |
|
| Chronic exposure of 2,2',4,4'-tetrabromodiphenyl ether (PBDE-47) alters locomotion behavior in juvenile zebrafish (Danio rerio). | 2010-07-15 |
|
| Placental transfer of the polybrominated diphenyl ethers BDE-47, BDE-99 and BDE-209 in a human placenta perfusion system: an experimental study. | 2010-07-05 |
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| Mechanism of polybrominated diphenyl ether uptake into the liver: PBDE congeners are substrates of human hepatic OATP transporters. | 2010-06 |
|
| Cytotoxicity and apoptosis induction on RTG-2 cells of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) and decabrominated diphenyl ether (BDE-209). | 2010-06 |
|
| Changes in mitogen-activated protein kinase in cerebellar granule neurons by polybrominated diphenyl ethers and polychlorinated biphenyls. | 2010-05-15 |
|
| Flow cytometric analysis of BDE 47 mediated injury to rainbow trout gill epithelial cells. | 2010-04-01 |
|
| Growth and transcriptional effect of dietary 2,2',4,4'-tetrabromodiphenyl ether (PBDE-47) exposure in developing zebrafish (Danio rerio). | 2010-03 |
|
| Global gene expression analysis in the livers of rat offspring perinatally exposed to low doses of 2,2',4,4'-tetrabromodiphenyl ether. | 2010-01 |
|
| Prenatal exposure to organohalogens, including brominated flame retardants, influences motor, cognitive, and behavioral performance at school age. | 2009-12 |
|
| Mechanisms underlying the developmental neurotoxic effect of PBDE-47 and the enhanced toxicity associated with its combination with PCB153 in rats. | 2009-11 |
|
| Immunoassay for monitoring environmental and human exposure to the polybrominated diphenyl ether BDE-47. | 2009-10-15 |
|
| Site-specific impacts on gene expression and behavior in fathead minnows (Pimephales promelas) exposed in situ to streams adjacent to sewage treatment plants. | 2009-10-08 |
|
| Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells. | 2009-08 |
|
| Perinatal exposure to low-dose 2,2',4,4'-tetrabromodiphenyl ether affects growth in rat offspring: what is the role of IGF-1? | 2009-06-16 |
|
| In vitro hepatic metabolism of 2,2',4,4',5-pentabromodiphenyl ether (BDE 99) in Chinook salmon (Onchorhynchus tshawytscha). | 2009-05-17 |
|
| Examining the role of temperature and sediment-chemical contact time on desorption and bioavailability of sediment-associated tetrabromo diphenyl ether and benzo(a)pyrene. | 2009-05 |
|
| Transcriptional effects of nonylphenol, bisphenol A and PBDE-47 in liver of juvenile Atlantic cod (Gadus morhua). | 2009-04 |
|
| Preliminary evidence of the in vitro effects of BDE-47 on innate immune responses in children with autism spectrum disorders. | 2009-03-31 |
|
| Cytotoxicity and gene expression profiling of two hydroxylated polybrominated diphenyl ethers in human H295R adrenocortical carcinoma cells. | 2009-02-25 |
|
| Recombinant transthyretin purification and competitive binding with organohalogen compounds in two gull species (Larus argentatus and Larus hyperboreus). | 2009-02 |
|
| Mechanism of the neurotoxic effect of PBDE-47 and interaction of PBDE-47 and PCB153 in enhancing toxicity in SH-SY5Y cells. | 2009-01 |
|
| Influence of PCB153 on oxidative DNA damage and DNA repair-related gene expression induced by PBDE-47 in human neuroblastoma cells in vitro. | 2009-01 |
|
| Dietary exposure to 2,2',4,4'-tetrabromodiphenyl ether (PBDE-47) alters thyroid status and thyroid hormone-regulated gene transcription in the pituitary and brain. | 2008-12 |
|
| Facing the challenge of data transfer from animal models to humans: the case of persistent organohalogens. | 2008-11-13 |
|
| Photodegradation of 2,2',4,4'-tetrabromodiphenyl ether in nonionic surfactant solutions. | 2008-11 |
|
| A technical mixture of 2,2',4,4'-tetrabromo diphenyl ether (BDE47) and brominated furans triggers aryl hydrocarbon receptor (AhR) mediated gene expression and toxicity. | 2008-09 |
|
| Multixenobiotic resistance, acetyl-choline esterase activity and total oxyradical scavenging capacity of the Arctic spider crab, Hyasaraneus, following exposure to bisphenol A, tetra bromo diphenyl ether and diallyl phthalate. | 2008-08 |
|
| Concentration of polybrominated diphenyl ethers (PBDEs) in household dust from various countries. | 2008-08 |
|
| Toxicity and physiological effects of brominated flame retardant PBDE-47 on two life stages of grass shrimp, Palaemonetes pugio. | 2008-07-25 |
|
| A cohort study of in utero polychlorinated biphenyl (PCB) exposures in relation to secondary sex ratio. | 2008-07-15 |
|
| Biomonitoring of polybrominated diphenyl ether (PBDE) pollution: a field study. | 2008-07 |
|
| Comparative oxygen radical formation and toxicity of BDE 47 in rainbow trout cell lines. | 2008-07 |
|
| Microarray analysis reveals a mechanism of phenolic polybrominated diphenylether toxicity in zebrafish. | 2008-03-01 |
|
| Gene expression profiles in rainbow trout, Onchorynchus mykiss, exposed to a simple chemical mixture. | 2008-03 |
|
| Serum concentrations of polybrominated diphenyl ethers (PBDEs) and polybrominated biphenyl (PBB) in the United States population: 2003-2004. | 2008-02-15 |
|
| Reductive debromination of polybrominated diphenyl ethers in anaerobic sediment and a biomimetic system. | 2008-02-15 |
|
| Effects of 20 PBDE metabolites on steroidogenesis in the H295R cell line. | 2008-02-15 |
|
| Inhibition of human placental aromatase activity by hydroxylated polybrominated diphenyl ethers (OH-PBDEs). | 2008-02-15 |
|
| Possible mechanisms of thyroid hormone disruption in mice by BDE 47, a major polybrominated diphenyl ether congener. | 2008-02-01 |
|
| Determination of brominated flame retardants and brominated dioxins in fish collected from three regions of Japan. | 2008-02 |
|
| Biotransformation of brominated flame retardants into potentially endocrine-disrupting metabolites, with special attention to 2,2',4,4'-tetrabromodiphenyl ether (BDE-47). | 2008-02 |
|
| Effects of PBDE-47 on cytotoxicity and genotoxicity in human neuroblastoma cells in vitro. | 2008-01-08 |
|
| The role of mitochondrial and oxidative injury in BDE 47 toxicity to human fetal liver hematopoietic stem cells. | 2008-01 |
|
| Flame retardants in placenta and breast milk and cryptorchidism in newborn boys. | 2007-10 |
|
| Debromination of polybrominated diphenyl ether-99 (BDE-99) in carp (Cyprinus carpio) microflora and microsomes. | 2007-10 |
|
| Bioaccumulation and biotransformation of 61 polychlorinated biphenyl and four polybrominated diphenyl ether congeners in juvenile American kestrels (Falco sparverius). | 2007-02 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:06:33 GMT 2025
by
admin
on
Mon Mar 31 21:06:33 GMT 2025
|
| Record UNII |
0N97R5X10X
|
| Record Status |
Validated (UNII)
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| Record Version |
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m8951
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0N97R5X10X
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