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AGANIRSEN
0N3FY8225K
Investigational
General
Record Details
Names
5
Classification
5
Identifiers
9
Subunits
1
Sugars
1
Linkages
1
Characteristic Attributes
1
AGANIRSEN
0N3FY8225K
Investigational
General
Approval Year
Unknown
139,594
Record Details
Substance Class
Nucleic Acid
Nucleic Acid Subtype
Sequence Type
OLIGONUCLEOTIDE
Record UNII
0N3FY8225K
Record Status
Validated (UNII)
Record Version
15
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Names
5
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entries
Name
Type
Language
Name
Type
Language
AGANIRSEN
Official Name
English
(3'->5')D(P-THIO)(T-A-T-C-C-G-G-A-G-G-G-C-T-C-G-C-C-A-T-G-C-T G-C-T)
Common Name
English
Aganirsen [WHO-DD]
Common Name
English
GS-101
Common Name
English
aganirsen [INN]
Common Name
English
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Classification
5
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Classification Tree
Code System
Code
Classification Tree
Code System
Code
Designated
ORPHAN DRUG
Designated
Prevention of corneal graft rejection.
FDA ORPHAN DRUG
500515
Gene Therapy Agent
Pharmacologic Substance
[C1909]
Biological Agent
[C307]
Gene Therapy Agent
[C1962]
Antisense Oligonucleotides
NCI_THESAURUS
C1291
Positive
EU ORPHAN DRUG
Positive
Treatment of central retinal vein occlusion
EU-Orphan Drug
EU/03/14/1275
Combination Medication
Pharmacologic Substance
[C1909]
Combination Medication
[C29629]
Topical Preparation
NCI_THESAURUS
C29639
Antineoplastic Agent
Pharmacologic Substance
[C1909]
Antineoplastic Agent
[C274]
Angiogenesis Inhibitor
NCI_THESAURUS
C1742
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Identifiers
9
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Code System
Code
Type
Description
Code System
Code
Type
Description
ChEMBL
CHEMBL2108296
PRIMARY
FDA UNII
0N3FY8225K
PRIMARY
NCI_THESAURUS
C148131
PRIMARY
WIKIPEDIA
Aganirsen
PRIMARY
EVMPD
SUB129665
PRIMARY
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Subunits
1
Subunit 0
>SUBUNIT_0
Sugars
1
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Sugar
Site Range
Site Count
Sugar
Site Range
Site Count
Deoxyribose (DNA)
1_1-1_25
25 / 25
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Linkages
1
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entries
Linkage
Site Range
Site Count
Linkage
Site Range
Site Count
Phosporothioate
1_2-1_25
24 / 24
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Characteristic Attributes
1
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Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
MOL_WEIGHT:NUMBER(CALCULATED)
CHEMICAL
NUMBER 8035 AMU (average)
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