URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 2B7

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 10:46:32 GMT 2023` Edited by `admin` on `Sat Dec 16 10:46:32 GMT 2023`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	0M77ZW789J
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 2B7

Common Name

English

UGT2B7

Common Name

English

UDP-GLUCURONOSYLTRANSFERASE-2B7

Common Name

English

UGT2B9

Common Name

English

UDPGT-2B7

Common Name

English

UDP-GLUCURONOSYLTRANSFERASE-2B9

Common Name

English

3,4-CATECHOL ESTROGEN-SPECIFIC UDPGT

Common Name

English

Code System Code Type Description

FDA UNII

0M77ZW789J

Created by admin on Sat Dec 16 10:46:35 GMT 2023 , Edited by admin on Sat Dec 16 10:46:35 GMT 2023

PRIMARY

EC (ENZYME CLASS)

EC 2.4.1.17

Created by admin on Sat Dec 16 10:46:35 GMT 2023 , Edited by admin on Sat Dec 16 10:46:35 GMT 2023

PRIMARY

WIKIPEDIA

UGT2B7

Created by admin on Sat Dec 16 10:46:35 GMT 2023 , Edited by admin on Sat Dec 16 10:46:35 GMT 2023

PRIMARY

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_44
N	1_45
N	1_292

Related Record Type Details


					5YL4IQ1078

OSILODROSTAT

SUBSTRATE -> METABOLIC ENZYME


					V5F60UPD8P

DENOPAMINE

SUBSTRATE -> METABOLIC ENZYME


					P5T6BYS22Y

LICOFELONE

SUBSTRATE -> METABOLIC ENZYME


					19GBJ60SN5

CANNABIDIOL

SUBSTRATE -> METABOLIC ENZYME

Amount:


					VJT6J7R4TR

RIFAMPIN

INDUCER -> METABOLIC ENZYME


					1EJ6Z6Q368

BEMPEDOIC ACID

SUBSTRATE -> METABOLIC ENZYME

Amount:


					HDC1R2M35U

EMPAGLIFLOZIN

SUBSTRATE -> METABOLIC ENZYME


					0QTW8Z7MCR

ROFECOXIB

SUBSTRATE -> METABOLIC ENZYME


					6783M2LV5X

PEXIDARTINIB

INHIBITOR -> METABOLIC ENZYME

Qualification:

IC50

Amount:


					0ES1C2KQ94

SELICICLIB

SUBSTRATE -> METABOLIC ENZYME

Amount:


					58IFB293JI

VORINOSTAT

SUBSTRATE -> METABOLIC ENZYME

Amount:


					36B82AMQ7N

NALOXONE

SUBSTRATE -> METABOLIC ENZYME


					5S371K6132

RIVOCERANIB

SUBSTRATE -> METABOLIC ENZYME

Amount:


					66974FR9Q1

CHLORAMPHENICOL

SUBSTRATE -> METABOLIC ENZYME

Interaction Type:

MAJOR


					8FG9H9D31J

TAFAMIDIS

SUBSTRATE -> METABOLIC ENZYME

Interaction Type:

MINOR

Amount:


					12WJ62D047

VERINURAD

SUBSTRATE -> METABOLIC ENZYME


					3A3N0634Q6

RIVOGLITAZONE

SUBSTRATE -> METABOLIC ENZYME


					144O8QL0L1

DICLOFENAC

INHIBITOR -> METABOLIC ENZYME

Interaction Type:

POTENT


					UC7ILE15NN

2,3,7-TRICHLORODIBENZO-P-DIOXIN

SUBSTRATE -> METABOLIC ENZYME


					S7946O4P76

SESAMIN

SUBSTRATE -> METABOLIC ENZYME

Interaction Type:

MAJOR


					9RL37ZZ665

ORANTINIB

SUBSTRATE -> METABOLIC ENZYME


					4B9XT59T7S

ZIDOVUDINE

SUBSTRATE -> METABOLIC ENZYME


					62XCK0G93T

ORNIDAZOLE

SUBSTRATE -> METABOLIC ENZYME

Interaction Type:

MAJOR


					101V0R1N2E

FEBUXOSTAT

SUBSTRATE -> METABOLIC ENZYME


					2U23G6VNUZ

PRADIGASTAT

SUBSTRATE -> METABOLIC ENZYME


					Z5MR2Y1IJJ

ENAVOGLIFLOZIN

SUBSTRATE -> METABOLIC ENZYME

Amount:


					W6HS99O8ZO

VARENICLINE

SUBSTRATE -> METABOLIC ENZYME

Amount:


					7S5I7G3JQL

DEXAMETHASONE

INDUCER -> METABOLIC ENZYME


					5G7AKV2MKP

PONESIMOD

SUBSTRATE -> METABOLIC ENZYME

Amount:


					48I5LU4ZWD

MECLOFENAMIC ACID

INHIBITOR -> METABOLIC ENZYME

Interaction Type:

POTENT


					8VZV102JFY

FLUCONAZOLE

METABOLIC ENZYME -> INHIBITOR

Interaction Type:

POTENT


					R3ZGC15A9A

LERSIVIRINE

SUBSTRATE -> METABOLIC ENZYME

Interaction Type:

MAJOR


					637E494O0Z

LORCASERIN

SUBSTRATE -> METABOLIC ENZYME

Amount:


					NM2KXJ990T

NEBICAPONE

SUBSTRATE -> METABOLIC ENZYME

Interaction Type:

MINOR


					53PF01Q249

CLOFIBRIC ACID

SUBSTRATE -> METABOLIC ENZYME


					VD2YSN1AFD

OLODATEROL

SUBSTRATE -> METABOLIC ENZYME


					614OI1Z5WI

VALPROIC ACID

SUBSTRATE -> METABOLIC ENZYME


					ER29L26N1X

COBIMETINIB

SUBSTRATE -> METABOLIC ENZYME


					144O8QL0L1

DICLOFENAC

SUBSTRATE -> METABOLIC ENZYME

Interaction Type:

POTENT


					2PEX5N7DQ4

FEVIPIPRANT

SUBSTRATE -> METABOLIC ENZYME

Amount:


					YQE403BP4D

PHENOBARBITAL

INDUCER -> METABOLIC ENZYME


					7J8897W37S

DRONABINOL

SUBSTRATE -> METABOLIC ENZYME

Amount:


					7LKK855W8I

LETROZOLE

SUBSTRATE -> METABOLIC ENZYME

Amount:


					A74586SNO7

CLOPIDOGREL

SUBSTRATE -> METABOLIC ENZYME

Comments:

UGT2B7 is the main enzyme involved in clopidogrel carboxylic acid glucuronidation in the liver

Amount:


					367589PJ2C

MEFENAMIC ACID

INHIBITOR -> METABOLIC ENZYME


					KG60484QX9

OMEPRAZOLE

INDUCER -> METABOLIC ENZYME


					P85X70RZWS

CENOBAMATE

SUBSTRATE -> METABOLIC ENZYME

Interaction Type:

MAJOR

Amount:


					S39XZ5QV8Y

BREXANOLONE

SUBSTRATE -> METABOLIC ENZYME


					UX6OWY2V7J

CODEINE ANHYDROUS

SUBSTRATE -> METABOLIC ENZYME


					G70A8514T8

FALECALCITRIOL

SUBSTRATE -> METABOLIC ENZYME

Interaction Type:

MINOR


					S798V6YJRP

EDARAVONE

SUBSTRATE -> METABOLIC ENZYME


					3T1SS4E7AG

ENASIDENIB

SUBSTRATE -> METABOLIC ENZYME


					64Y9KYM60R

MORPHINE-6-GLUCURONIDE

SUBSTRATE -> METABOLIC ENZYME


					N62TGJ04A1

ESAXERENONE

SUBSTRATE -> METABOLIC ENZYME

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER AVERAGE(CALCULATED)	CHEMICAL