LORPIPRAZOLE

Details

Stereochemistry	RACEMIC
Molecular Formula	C21H26F3N5
Molecular Weight	405.4598
Optical Activity	( + / - )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@]12CCC[C@@]1([H])C3=NN=C(CCN4CCN(CC4)C5=CC=CC(=C5)C(F)(F)F)N3C2

InChI

InChIKey=BNRMWKUVWLKDQJ-CRAIPNDOSA-N

InChI=1S/C21H26F3N5/c22-21(23,24)16-4-2-5-17(13-16)28-11-9-27(10-12-28)8-7-19-25-26-20-18-6-1-3-15(18)14-29(19)20/h2,4-5,13,15,18H,1,3,6-12,14H2/t15-,18-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C21H26F3N5
Molecular Weight	405.4598
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/23192413 | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 742, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | https://alchetron.com/Lorpiprazole

Lorpiprazole (brand name Normarex) is a marketed anxiolytic drug of the phenylpiperazine group. It has been described as a serotonin antagonist and reuptake inhibitor (SARI) in the same group as trazodone, nefazodone, and etoperidone.

Approval Year

PubMed

Title	Date	PubMed
Rediscovering trazodone for the treatment of major depressive disorder.	2012 Dec	23192413

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:11:30 GMT 2023` Edited by `admin` on `Fri Dec 15 16:11:30 GMT 2023`
Record UNII	0M14O7T47Q
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

LORPIPRAZOLE

Official Name

English

(±)-CIS-5,5A,6,7,8,8A-HEXAHYDRO-3-(2-(4-(.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-M-TOLYL)-1-PIPERAZINYL)ETHYL)CYCLOPENTA(3,4)PYRROLO(2,1-C)-S-TRIAZOLE

Common Name

English

lorpiprazole [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29710