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Description

AC-2592 (glucagon-like peptide 1, or GLP-1) was being in development by Amylin Pharmaceuticals for the treatment of severe congestive heart failure. AC-2592 is a glucagon like peptide 1 receptor agonist.

Originator

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
Gateways to clinical trials.
2010-05
Patents

Patents

08524726
5
20050070539
2
6756374
2
9212177
2
WO2011015037A1
2
WO2012044531A1
2
WO2013171334A1
2

Sample Use Guides

In Vivo Use Guide
Congestive Heart Failure: Continuous subcutaneous infusion (via pump), dose based on subject body weight
Route of Administration: Parenteral
Substance Class Protein
Created
by admin
on Wed Apr 02 05:34:20 GMT 2025
Edited
by admin
on Wed Apr 02 05:34:20 GMT 2025
Protein Type HORMONE
Protein Sub Type GLUCAGON-LIKE PEPTIDE
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
0JS9125PIZ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
GLUCAGON-LIKE PEPTIDE-I(7-36) AMIDE
Common Name English
AC-2592
Preferred Name English
HUMAN GLP-1-(7-36)-AMIDE
Common Name English
BETATROPIN
Common Name English
GLP-1(7-36)AMIDE
Common Name English
(7-36)GLUCAGON-LIKE PEPTIDE-1 AMIDE (HUMAN)
Common Name English
GLP-1(7-36)
Common Name English
MKC 253
Code English
RAT GLP-I(7-36)AMIDE
Common Name English
GLP-1 (7-36) AMIDE
Common Name English
GLUCAGON-LIKE-PEPTIDE-1 (7-36) AMIDE
Common Name English
INSULINOTROPIN (HUMAN)
Common Name English
HUMAN GLUCAGON-LIKE PEPTIDE-1-(7-36) AMIDE
Common Name English
7-36-HUMAN GLUCAGON-LIKE PEPTIDE I AMIDE
Common Name English
GLUCAGON-LIKE PEPTIDE-I (7-36)
Common Name English
Code System Code Type Description
PUBCHEM
16133831
Created by admin on Wed Apr 02 05:34:20 GMT 2025 , Edited by admin on Wed Apr 02 05:34:20 GMT 2025
PRIMARY
CAS
107444-51-9
Created by admin on Wed Apr 02 05:34:20 GMT 2025 , Edited by admin on Wed Apr 02 05:34:20 GMT 2025
PRIMARY
FDA UNII
0JS9125PIZ
Created by admin on Wed Apr 02 05:34:20 GMT 2025 , Edited by admin on Wed Apr 02 05:34:20 GMT 2025
PRIMARY
MANUFACTURER PRODUCT INFORMATION
GLUCAGON-LIKE PEPTIDE-I(7-36) AMIDE
Created by admin on Wed Apr 02 05:34:20 GMT 2025 , Edited by admin on Wed Apr 02 05:34:20 GMT 2025
PRIMARY
Related Record Type Details
GLUCAGON-LIKE PEPTIDE-I(7-36) AMIDE ACETATE
SALT/SOLVATE -> PARENT
Related Record Type Details
GLUCAGON-LIKE PEPTIDE-I(7-36) AMIDE
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO_ACID_SUBSTITUTION [1_30] C-TERMINUS ARGININAMIDE, L- 29626ZE0WY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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