U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:51:27 GMT 2023
Edited
by admin
on Sat Dec 16 14:51:27 GMT 2023
Protein Type ENZYME
Protein Sub Type
Sequence Origin BACTERIAL
Sequence Type COMPLETE
Record UNII
0JMN4Q4EUY
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CARBAPENEM-HYDROLYZING BETA-LACTAMASE KPC
Common Name English
CARBAPENEM-HYDROLYZING BETA-LACTAMASE KPC-1
Common Name English
KPC-2
Common Name English
KPC
Common Name English
KPC-1
Common Name English
KPC2
Common Name English
KPC1
Common Name English
Code System Code Type Description
UNIPROT
Q9F663
Created by admin on Sat Dec 16 14:51:27 GMT 2023 , Edited by admin on Sat Dec 16 14:51:27 GMT 2023
PRIMARY
EC (ENZYME CLASS)
EC 3.5.2.6
Created by admin on Sat Dec 16 14:51:27 GMT 2023 , Edited by admin on Sat Dec 16 14:51:27 GMT 2023
PRIMARY
FDA UNII
0JMN4Q4EUY
Created by admin on Sat Dec 16 14:51:27 GMT 2023 , Edited by admin on Sat Dec 16 14:51:27 GMT 2023
PRIMARY
Related Record Type Details
INHIBITOR -> TARGET
Inhibits but does not undergo hydrolysis.
Ki
SUBSTRATE->ENZYME
Inactivates antibacterial activity
APICAL
INHIBITOR -> TARGET
KOFF=0.000017 (1/S), RESIDENCE TIME=992 (MIN), STOICHIOMETRY=1
REVERSIBLE
Kd
INHIBITOR -> TARGET
koff
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL