POZELIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 22:46:01 GMT 2025` Edited by `admin` on `Tue Apr 01 22:46:01 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	0JJ21K6L2I
Record Status	`Validated (UNII)`
Record Version

Download

Related Record	Type

Name

Type

Language

REGN-3918

Preferred Name

English

POZELIMAB

Official Name

English

IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS C5 (COMPLEMENT C5)), HOMO SAPIENS MONOCLONAL ANTIBODYGAMMA4 HEAVY CHAIN HOMO SAPIENS (1-447) (VH (HOMO SAPIENS IGHV4-59*02 (94.8%)-(IGHD)-IGHJ4*01 (100%)) (8.7.14) (1-120)-HOMO SAPIENS IGHG4*01 (CH1 (121-218),

Systematic Name

English

REGN3918

Code

English

POZELIMAB [USAN]

Common Name

English

Pozelimab [WHO-DD]

Common Name

English

pozelimab [INN]

Common Name

English

IMMUNOGLOBULIN G4 (228-PROLINE), ANTI-(HUMAN COMPLEMENT C5) (HUMAN MONOCLONAL REGN3918 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL REGN3918 .KAPPA.-CHAIN, DIMER

Systematic Name

English

IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS COMPLEMENT C5)HUMAN MONOCLONAL ANTIBODY.GAMMA.4 HEAVY CHAIN (1-447) (HOMO SAPIENS VH (IGHV4-59*02 (95%) (IGHD)-IGHJ4*01) (8.7.14) (1-120)-HOMO SAPIENS IGHG4*01 (HINGE(S10>P(228))) (121-447)) (134-214')-DISULFID

Systematic Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

736820

Created by admin on Tue Apr 01 22:46:01 GMT 2025 , Edited by admin on Tue Apr 01 22:46:01 GMT 2025

FDA ORPHAN DRUG

660518

Created by admin on Tue Apr 01 22:46:01 GMT 2025 , Edited by admin on Tue Apr 01 22:46:01 GMT 2025

FDA ORPHAN DRUG

760920

Created by admin on Tue Apr 01 22:46:01 GMT 2025 , Edited by admin on Tue Apr 01 22:46:01 GMT 2025

Code System Code Type Description

NCI_THESAURUS

C166423

Created by admin on Tue Apr 01 22:46:01 GMT 2025 , Edited by admin on Tue Apr 01 22:46:01 GMT 2025

PRIMARY

DAILYMED

0JJ21K6L2I

Created by admin on Tue Apr 01 22:46:01 GMT 2025 , Edited by admin on Tue Apr 01 22:46:01 GMT 2025

PRIMARY

INN

10945

Created by admin on Tue Apr 01 22:46:01 GMT 2025 , Edited by admin on Tue Apr 01 22:46:01 GMT 2025

PRIMARY

USAN

FG-06

Created by admin on Tue Apr 01 22:46:01 GMT 2025 , Edited by admin on Tue Apr 01 22:46:01 GMT 2025

PRIMARY

CAS

2096328-94-6

Created by admin on Tue Apr 01 22:46:01 GMT 2025 , Edited by admin on Tue Apr 01 22:46:01 GMT 2025

PRIMARY

DRUG BANK

DB15218

Created by admin on Tue Apr 01 22:46:01 GMT 2025 , Edited by admin on Tue Apr 01 22:46:01 GMT 2025

PRIMARY

SMS_ID

300000005406

Created by admin on Tue Apr 01 22:46:01 GMT 2025 , Edited by admin on Tue Apr 01 22:46:01 GMT 2025

PRIMARY

FDA UNII

0JJ21K6L2I

Created by admin on Tue Apr 01 22:46:01 GMT 2025 , Edited by admin on Tue Apr 01 22:46:01 GMT 2025

PRIMARY

From	To
1_22	1_95
2_22	2_95
3_23	3_88
4_23	4_88
3_134	3_194
4_134	4_194
1_134	3_214
2_134	4_214
1_147	1_203
2_147	2_203
1_226	2_226
1_229	2_229
1_261	1_321
2_261	2_321
1_367	1_425
2_367	2_425

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_297
N	2_297

Related Record Type Details

SUB_CONCEPT->SUBSTANCE

Amount:


					7A6G4V3R84

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					0JJ21K6L2I

POZELIMAB

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL