Approval Year
| Substance Class |
Nucleic Acid
Created
by
admin
on
Edited
Sat Dec 16 13:27:14 GMT 2023
by
admin
on
Sat Dec 16 13:27:14 GMT 2023
|
| Nucleic Acid Type | OLIGONUCLEOTIDE |
| Nucleic Acid Subtype | |
| Sequence Type | COMPLETE |
| Record UNII |
0IEO0F56LV
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Official Name | English | ||
|
Common Name | English | ||
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Common Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Code | English | ||
|
Common Name | English | ||
|
Code | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
FDA ORPHAN DRUG |
374512
Created by
admin on Sat Dec 16 13:27:14 GMT 2023 , Edited by admin on Sat Dec 16 13:27:14 GMT 2023
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
2099289
Created by
admin on Sat Dec 16 13:27:14 GMT 2023 , Edited by admin on Sat Dec 16 13:27:14 GMT 2023
|
PRIMARY | |||
|
1492984-65-2
Created by
admin on Sat Dec 16 13:27:14 GMT 2023 , Edited by admin on Sat Dec 16 13:27:14 GMT 2023
|
PRIMARY | |||
|
Inotersen
Created by
admin on Sat Dec 16 13:27:14 GMT 2023 , Edited by admin on Sat Dec 16 13:27:14 GMT 2023
|
PRIMARY | |||
|
5319
Created by
admin on Sat Dec 16 13:27:14 GMT 2023 , Edited by admin on Sat Dec 16 13:27:14 GMT 2023
|
PRIMARY | |||
|
10294
Created by
admin on Sat Dec 16 13:27:14 GMT 2023 , Edited by admin on Sat Dec 16 13:27:14 GMT 2023
|
PRIMARY | |||
|
0IEO0F56LV
Created by
admin on Sat Dec 16 13:27:14 GMT 2023 , Edited by admin on Sat Dec 16 13:27:14 GMT 2023
|
PRIMARY | |||
|
m12102
Created by
admin on Sat Dec 16 13:27:14 GMT 2023 , Edited by admin on Sat Dec 16 13:27:14 GMT 2023
|
PRIMARY | |||
|
0IEO0F56LV
Created by
admin on Sat Dec 16 13:27:14 GMT 2023 , Edited by admin on Sat Dec 16 13:27:14 GMT 2023
|
PRIMARY | |||
|
CD-06
Created by
admin on Sat Dec 16 13:27:14 GMT 2023 , Edited by admin on Sat Dec 16 13:27:14 GMT 2023
|
PRIMARY | |||
|
DB14713
Created by
admin on Sat Dec 16 13:27:14 GMT 2023 , Edited by admin on Sat Dec 16 13:27:14 GMT 2023
|
PRIMARY | |||
|
DTXSID501027905
Created by
admin on Sat Dec 16 13:27:14 GMT 2023 , Edited by admin on Sat Dec 16 13:27:14 GMT 2023
|
PRIMARY | |||
|
121492004
Created by
admin on Sat Dec 16 13:27:14 GMT 2023 , Edited by admin on Sat Dec 16 13:27:14 GMT 2023
|
PRIMARY | |||
|
C121667
Created by
admin on Sat Dec 16 13:27:14 GMT 2023 , Edited by admin on Sat Dec 16 13:27:14 GMT 2023
|
PRIMARY |
| Sugar | Site Range | Site Count |
|---|---|---|
| Deoxyribose (DNA) | 1_6-1_15 | 10 / 20 |
| 2'-O-Methoxyethyl ribose | 1_1-1_5;1_16-1_20 | 10 / 20 |
| Linkage | Site Range | Site Count |
|---|---|---|
| Phosporothioate | 1_2-1_20 | 19 / 19 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
SALT/SOLVATE -> PARENT | |||
|
TARGET->INHIBITOR OF EXPRESSION | |||
|
TARGET->INHIBITOR OF EXPRESSION |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |
Structural Modifications
| Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
|---|---|---|---|---|---|---|
| NUCLEOSIDE SUBSTITUTION | [1_2] [1_18] [1_19] [1_20] | C | 2'-O-(2-METHOXYETHYL)-5-METHYLCYTIDINE | AOQ54IZZ6J | ||
| NUCLEOSIDE SUBSTITUTION | [1_10] | C | 5-METHYLDEOXYCYTIDINE | B200GV71QM | ||
| NUCLEOSIDE SUBSTITUTION | [1_1] [1_3] [1_4] [1_17] | U | 2'-O-(2-METHOXYETHYL)-5-METHYLURIDINE | 9Q36I4D9VB |