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CGMP-DEPENDENT PROTEIN KINASE 1
0GTQ39868X
Other
General
Record Details
Names
9
Identifiers
5
Subunits
2
Disulfide Links
1
Relationships
6
Modifications
3
Characteristic Attributes
2
CGMP-DEPENDENT PROTEIN KINASE 1
0GTQ39868X
Other
General
Approval Year
Unknown
149,124
Record Details
Substance Class
Protein
Protein Sub Type
Sequence Type
COMPLETE
Record UNII
0GTQ39868X
Record Status
Validated (UNII)
Record Version
5
4
3
2
1
Names
9
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entries
Name
Type
Language
Name
Type
Language
CGMP-DEPENDENT PROTEIN KINASE 1
Common Name
English
CGK1
Preferred Name
English
CGK1-ALPHA
Common Name
English
PRKGR1B
Common Name
English
PRKG1B
Common Name
English
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Identifiers
5
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entries
Code System
Code
Type
Description
Code System
Code
Type
Description
EC (ENZYME CLASS)
EC 2.7.11.12
PRIMARY
UNIPROT
Q13976
PRIMARY
PHAROS
Q13976
PRIMARY
WIKIPEDIA
PRKG1
PRIMARY
FDA UNII
0GTQ39868X
PRIMARY
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Subunits
2
Subunit 0
>SUBUNIT_0
Subunit 1
>SUBUNIT_1
Disulfide Links
1
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entries
From
To
From
To
1_42
2_42
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Relationships
6
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entries
Related Record
Type
Details
Related Record
Type
Details
524Y3IB4HQ
IPATASERTIB
INHIBITOR -> TARGET
2DW6Y8OU16
NOP-46 C-11
RADIOLIGAND->TARGET
GWH480321B
GSK-690693
INHIBITOR -> TARGET
Comments:
PKG1.beta.
Interaction Type:
IN-VITRO
Qualification:
IC50
Amount:
RELATIONSHIP_AMOUNT 33 NANOMOLAR (average)
524Y3IB4HQ
IPATASERTIB
INHIBITOR -> TARGET
Comments:
IC50(PRKG1.beta.)=69 nM
Interaction Type:
IN-VITRO
Qualification:
IC50
Amount:
RELATIONSHIP_AMOUNT 98 NANOMOLAR (average)
GR20O32F2J
NOP-46
LIGAND->BINDER
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Modifications
3
Structural Modifications
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Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
AMINO ACID SUBSTITUTION
[1_58] [2_58]
THREONINE
THREONINE PHOSPHATE
3L4WX7B1EI
AMINO ACID SUBSTITUTION
[1_514] [2_514]
THREONINE
THREONINE PHOSPHATE
3L4WX7B1EI
AMINO ACID SUBSTITUTION
[1_1] [2_1]
SERINE
N-ACETYLSERINE
W98518XGZ3
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Characteristic Attributes
2
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Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Molecular Formula
CHEMICAL
ESTIMATED
C6844H10724N1804O2054P4S52
MOL_WEIGHT
CHEMICAL
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