Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 13:50:10 GMT 2023
by
admin
on
Sat Dec 16 13:50:10 GMT 2023
|
| Protein Type | ENZYME |
| Protein Sub Type | PHOSPHODIESTERASE |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
0FY8X1RL72
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
P27815
Created by
admin on Sat Dec 16 13:50:11 GMT 2023 , Edited by admin on Sat Dec 16 13:50:11 GMT 2023
|
PRIMARY | |||
|
0FY8X1RL72
Created by
admin on Sat Dec 16 13:50:11 GMT 2023 , Edited by admin on Sat Dec 16 13:50:11 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR -> TARGET |
Representative of PDE4
|
||
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR -> TARGET |
IC50
|
||
|
INHIBITOR -> TARGET |
2-3 fold less active than ROFLUMILAST but much higher concentration in plasma.
|
||
|
|
INHIBITOR -> TARGET | |||
|
INHIBITOR -> TARGET |
|
||
|
|
INHIBITOR -> TARGET |
No specific PDE4 mentioned. Designed as a soft drug but lead to active metabolites.
IC50
|
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
|