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Details

Stereochemistry ACHIRAL
Molecular Formula C3H6Cl2O
Molecular Weight 128.985
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1,3-Dichloro-2-propanol

SMILES

OC(CCl)CCl

InChI

InChIKey=DEWLEGDTCGBNGU-UHFFFAOYSA-N
InChI=1S/C3H6Cl2O/c4-1-3(6)2-5/h3,6H,1-2H2

HIDE SMILES / InChI

Molecular Formula C3H6Cl2O
Molecular Weight 128.985
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
1,3-Dichloro-2-propanol inhibits progesterone production through the expression of steroidogenic enzymes and cAMP concentration in Leydig cells.
2014-07-01
1,3-Dichloro-2-propanol induced hyperlipidemia in C57BL/6J mice via AMPK signaling pathway.
2014-02
Antioxidant Vitamins and Lipoperoxidation in Non-pregnant, Pregnant, and Gestational Diabetic Women: Erythrocytes Osmotic Fragility Profiles.
2010-12-11
Migration studies of 3-chloro-1,2-propanediol (3-MCPD) in polyethylene extrusion-coated paperboard food packaging.
2010-06
A high-throughput colorimetric assay for screening halohydrin dehalogenase saturation mutagenesis libraries.
2010-06
Application of the margin of exposure (MoE) approach to substances in food that are genotoxic and carcinogenic: example: (CAS No. 96-23-1) 1,3-dichloro-2-propanol (DCP).
2010-01
1,3-Dichloro-2-propanol induces apoptosis via both calcium and ROS in mouse melanoma cells.
2010-01
An evaluation of the chick cardiomyocyte micromass system for identification of teratogens in a blind trial.
2009-12
Solid-phase micro-extraction procedure for the determination of 1,3-dichloro-2-propanol in water by on-fibre derivatisation with bis(trimethylsilyl)trifluoroacetamide.
2009-06
Developmental toxic potential of 1,3-dichloro-2-propanol in Sprague-Dawley rats.
2009-02
[Research concerning rutin semisynthetic derivatives. Synthesis, physico-chemical and microbiological characterisation of some new rutin-isoniazid derivatives].
2008-08-06
[Gas chromatography for determination of 1, 3-dichloro-2-propanol in air of working places].
2008-08
Enrichment and characterization of chlorinated organophosphate ester-degrading mixed bacterial cultures.
2008-07
Identification of OBO nonalignments and its implications for OBO enrichment.
2008-06-15
subchronic inhalation toxicity study of 1,3-dichloro-2-propanol in rats.
2007-10
Occurrence of chloropropanols in soy sauce and other foods in China between 2002 and 2004.
2007-08
Photochemical degradation of 1,3-dichloro-2-propanol aqueous solutions.
2007-07-31
Determination of 1,3-dichloro-2-propanol and 3-chloro-1,2-propandiol in soy sauce by headspace derivatization solid-phase microextraction combined with gas chromatography-mass spectrometry.
2007-05-22
Evaluation of certain food additives and contaminants.
2007
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.
2006-11
Photocatalytical degradation of 1,3-dichloro-2-propanol aqueous solutions by using an immobilized TiO2 photoreactor.
2006-09-21
The simultaneous separation and determination of chloropropanols in soy sauce and other flavoring with gas chromatography-mass spectrometry in negative chemical and electron impact ionization modes.
2006-02
Determination of 1,3-dichloropropanol in soy sauce and related products by headspace gas chromatography with mass spectrometric detection: interlaboratory study.
2006-01-03
Removal of 1,3-dichloro2-propanol and 3-chloro1,2-propanediol by the whole cell system of pseudomonas putida DSM 437.
2006
A rapid and sensitive GC-MS method for determination of 1,3-dichloro-2-propanol in water.
2005-05
[Determination of residual epichlorohydrin and sym-dichloroisopropyl alcohol in cationic etherified reagent by gas chromatography].
2004-11
Structure and mechanism of a bacterial haloalcohol dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site.
2003-10-01
Survey of chloropropanols in soy sauces and related products purchased in the UK in 2000 and 2002.
2003-10
Survey of chloropropanols in soy sauces and related products.
2003-10
Determination of 1,3-dichloropropanol in soy and related sauces by using gas chromatography/mass spectrometry.
2003-10
[Toxicity of dichloropropanols].
2002-09-01
The relative embryotoxicity of 1,3-dichloro-2-propanol on primary chick embryonic cells.
2002-08
Modulation of hepatocyte thiol content by medium composition: implications for toxicity studies.
2002-06
Sensitive method for the determination of 1,3-dichloropropan-2-ol and 3-chloropropane-1,2-diol in soy sauce by capillary gas chromatography with mass spectrometric detection.
2002-04-05
Determination of 1,3-dichloropropanol in soy sauces by automated headspace gas chromatography-mass spectrometry.
2002-04
Enrichment of microbial cultures able to degrade 1,3-dichloro-2-propanol: a comparison between batch and continuous methods.
2002
A Genetically engineered cell-based system for detecting metabolism-mediated toxicity.
2001-11-16
Characterization of a novel enantioselective halohydrin hydrogen-halide-lyase.
1994-04
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:14:25 GMT 2025
Edited
by admin
on Mon Mar 31 19:14:25 GMT 2025
Record UNII
0F4P2VQC07
Record Status Validated (UNII)
Record Version
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Name Type Language
NSC-70982
Preferred Name English
1,3-Dichloro-2-propanol
HSDB   MI  
Systematic Name English
SYM-GLYCEROL DICHLOROHYDRIN
Common Name English
DICHLORO-2-PROPANOL, 1,3-
Systematic Name English
.ALPHA.-DICHLOROHYDRIN
Common Name English
1,3-DICHLORO-2-PROPANOL [HSDB]
Common Name English
1,3-DICHLORO-2-PROPANOL [IARC]
Common Name English
SYM-DICHLOROISOPROPYL ALCOHOL
Common Name English
1,3-DICHLORO-2-PROPANOL [MI]
Common Name English
GLYCEROL .ALPHA.,.GAMMA.-DICHLOROHYDRIN
Common Name English
Code System Code Type Description
NSC
70982
Created by admin on Mon Mar 31 19:14:25 GMT 2025 , Edited by admin on Mon Mar 31 19:14:25 GMT 2025
PRIMARY
MERCK INDEX
m4354
Created by admin on Mon Mar 31 19:14:25 GMT 2025 , Edited by admin on Mon Mar 31 19:14:25 GMT 2025
PRIMARY Merck Index
WIKIPEDIA
1,3-Dichloropropan-2-ol
Created by admin on Mon Mar 31 19:14:25 GMT 2025 , Edited by admin on Mon Mar 31 19:14:25 GMT 2025
PRIMARY
RXCUI
1305516
Created by admin on Mon Mar 31 19:14:25 GMT 2025 , Edited by admin on Mon Mar 31 19:14:25 GMT 2025
PRIMARY RxNorm
EPA CompTox
DTXSID6025010
Created by admin on Mon Mar 31 19:14:25 GMT 2025 , Edited by admin on Mon Mar 31 19:14:25 GMT 2025
PRIMARY
HSDB
5302
Created by admin on Mon Mar 31 19:14:25 GMT 2025 , Edited by admin on Mon Mar 31 19:14:25 GMT 2025
PRIMARY
ECHA (EC/EINECS)
202-491-9
Created by admin on Mon Mar 31 19:14:25 GMT 2025 , Edited by admin on Mon Mar 31 19:14:25 GMT 2025
PRIMARY
PUBCHEM
7289
Created by admin on Mon Mar 31 19:14:25 GMT 2025 , Edited by admin on Mon Mar 31 19:14:25 GMT 2025
PRIMARY
FDA UNII
0F4P2VQC07
Created by admin on Mon Mar 31 19:14:25 GMT 2025 , Edited by admin on Mon Mar 31 19:14:25 GMT 2025
PRIMARY
CHEBI
18917
Created by admin on Mon Mar 31 19:14:25 GMT 2025 , Edited by admin on Mon Mar 31 19:14:25 GMT 2025
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SMS_ID
300000052978
Created by admin on Mon Mar 31 19:14:25 GMT 2025 , Edited by admin on Mon Mar 31 19:14:25 GMT 2025
PRIMARY
MESH
C033489
Created by admin on Mon Mar 31 19:14:25 GMT 2025 , Edited by admin on Mon Mar 31 19:14:25 GMT 2025
PRIMARY
CAS
96-23-1
Created by admin on Mon Mar 31 19:14:25 GMT 2025 , Edited by admin on Mon Mar 31 19:14:25 GMT 2025
PRIMARY