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Details

Stereochemistry ACHIRAL
Molecular Formula C15H18N2O3
Molecular Weight 274.315
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TERBEQUINIL

SMILES

CCCNC(=O)C1=CN(COC)C2=C(C=CC=C2)C1=O

InChI

InChIKey=RIPDGZHPNKQLDC-UHFFFAOYSA-N
InChI=1S/C15H18N2O3/c1-3-8-16-15(19)12-9-17(10-20-2)13-7-5-4-6-11(13)14(12)18/h4-7,9H,3,8,10H2,1-2H3,(H,16,19)

HIDE SMILES / InChI

Molecular Formula C15H18N2O3
Molecular Weight 274.315
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Terbequinil (previously known as SR 25776), a nootropic agent, is a partial inverse agonist of benzodiazepine receptor with psychostimulant activity. This drug participated in clinical trials for the treatment of cognition disorders and major depressive disorder. However, the development of terbequinil was discontinued during clinical trials in France.

Originator

Approval Year

PubMed

Sample Use Guides

In Vivo Use Guide
The effects of SR 25776 (TERBEQUINIL) 500 mg alone and in combination with triazolam 0.25 mg on psychomotor performance and memory were assessed in 8 healthy consenting male volunteers in a double-blind placebo controlled trial
Route of Administration: Oral
Substance Class Chemical
Record UNII
0DH9WUS03O
Record Status Validated (UNII)
Record Version