Bezetabart Debotansine

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 15:04:04 GMT 2023` Edited by `admin` on `Sat Dec 16 15:04:04 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	0D8BWL78LD
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Bezetabart Debotansine

Official Name

English

Gamma1 heavy chain (1-454) [VH (Homo sapiens IGHV3-30-5*03 (95.9%) -(IGHD) -IGHJ6*01 (93.8%), CDR-IMGT [8.8.16] (27-34.52-59.98-113)) (1-124) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14 (CH1R120>K(221) (125-222), hinge 1-15 (223-237

Common Name

English

STRO-001

Code

English

Immunoglobulin G1, anti-(human CD74 antigen) (human monoclonal SP7219 γ1-chain), disulfide with human monoclonal SP7219 κ-chain, dimer, 411,411′-bis[4-[[8-(3-amino-1-oxopropyl)-8,9-dihydroxy-1H(or 3H)-dibenzo[b,f]-1,2,3-triazolo[4,5-d]azocin-1(or 3)-

Common Name

English

Immunoglobulin G1-kappa, anti-[Homo sapiens CD74 (major histocompatibility complex class II invariant chain)], monoclonal antibody, conjugated at C-4 of two specific phenylalanine residues with N2' -deacetylmaytansine via a non cleavable linker

Common Name

English

bezetabart debotansine [INN]

Common Name

English

ANTI-CD74 ANTIBODY-DRUG CONJUGATE STRO-001

Common Name

English

STRO-001, A SITE-SPECIFIC ANTI-CD74 ANTIBODY-DRUG CONJUGATE

Common Name

English

SP7675

Code

English

Classification Tree Code System Code

FDA ORPHAN DRUG

654118