PHENYL ISOTHIOCYANATE

Possibly Marketed Outside US

First approved in 2018

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H5NS
Molecular Weight	135.186
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

S=C=NC1=CC=CC=C1

InChI

InChIKey=QKFJKGMPGYROCL-UHFFFAOYSA-N

InChI=1S/C7H5NS/c9-6-8-7-4-2-1-3-5-7/h1-5H

HIDE SMILES / InChI

Molecular Formula	C7H5NS
Molecular Weight	135.186
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Year-long validation study and reference values for urinary amino acids using a reversed-phase HPLC method.	2001 Mar	11238314
Normal plasma free amino acid levels in Thai children.	2001 Nov	11853298
Synthesis of some new quinoline derivatives: new routes to synthesize polysubstituted 2(1H)-quinolone derivatives.	2001 Sep-Oct	11680080
Synthesis and antibacterial activity of fused 1, 2, 4-triazolo[4, 3-a]quinoxaline and oxopyrimido[2', 1':5, 1]-1, 2, 4-triazolo[4, 3-a]quinoxaline derivatives.	2002 Aug	12397623
Purification and characterization of the reconstitutively active adenine nucleotide carrier from mitochondria of Jerusalem artichoke (Helianthus tuberosus L.) tubers.	2002 Dec	12678438
[Simultaneous determination of 18 amino acids by reversed-phase high performance liquid chromatography with precolumn phenylisothiocyanate derivatization].	2002 Jul	12541928
Involvement of amino-acid side chains of membrane proteins in the binding of glutathione to pig cerebral cortical membranes.	2002 May	12064354
[(111)In]Bz-DTPA-hEGF: Preparation and in vitro characterization of a potential anti-glioblastoma targeting agent.	2003 Aug	14503960
Determination of amino acids in foods by reversed-phase HPLC with new precolumn derivatives, butylthiocarbamyl, and benzylthiocarbamyl derivatives compared to the phenylthiocarbamyl derivative and ion exchange chromatography.	2003 May	12721496
Synthesis and fungicidal activity of some 5-aryl/aryloxymethyl-2-[5-aryl-3-methyl-1,2,4-triazol-2-yl]-1,3,4-thiadiazoles and 5-aryl/aryloxymethyl-2[5-aryl-2-phenylimino-1,3,4- thiadiazolin-3-yl]-1,3,4-thiadiazoles.	2003 Nov	14971312
A glycosylated byssal precursor protein from the green mussel Perna viridis with modified dopa side-chains.	2004 Apr	15203964
Application of iodine-azide reaction for detection of amino acids in thin-layer chromatography.	2004 Dec 3	15628138
The facile HPLC enantioresolution of amino acids, peptides on naphthylethylcarbamate-beta-cyclodextrin bonded phases using the acetonitrile-based mobile phase after their pre-column derivatization with phenyl isothiocyanate: factors that affect the resolution.	2004 Jun	15221510
Photodissociation tandem mass spectrometry at 266 nm of an aliphatic peptide derivatized with phenyl isothiocyanate and 4-sulfophenyl isothiocyanate.	2005	15838844
Amino-functionalized ionic liquid as a nucleophilic scavenger in solution phase combinatorial synthesis.	2005 Jul-Aug	16004499
Structure investigation of Maltacine D1a, D1b and D1c-cyclic peptide lactones of the Maltacine complex from Bacillus subtilis.	2005 Oct	16178056
Citrate transporters play a critical role in aluminium-stimulated citrate efflux in rice bean (Vigna umbellata) roots.	2006 Apr	16446286
Improvement in isolation and identification of food-derived peptides in human plasma based on precolumn derivatization of peptides with phenyl isothiocyanate.	2006 Jul 26	16848504
The role of crude human saliva and purified salivary MUC5B and MUC7 mucins in the inhibition of Human Immunodeficiency Virus type 1 in an inhibition assay.	2006 Nov 24	17125499
Synthesis and biological evaluation of new 3-substituted indole derivatives as potential anti-inflammatory and analgesic agents.	2007 Jun 1	17395469
Isothiocyanato-calix[4]phyrin-(1,1,1,1): a useful intermediate for the synthesis of derivatised anion sensors.	2007 Jun 21	17551647
An easy synthesis of 5-functionally substituted ethyl 4-amino-1-aryl- pyrazolo-3-carboxylates: interesting precursors to sildenafil analogues.	2007 May 1	17470302
Synthesis and molluscicidal activity of new chromene and pyrano[2,3-c]pyrazole derivatives.	2007 Oct	17912679
Streptavidin in antibody pretargeting. 5. chemical modification of recombinant streptavidin for labeling with the alpha-particle-emitting radionuclides 213Bi and 211At.	2008 Jan	18072725
Isolation and characterization of a C12-lipopeptide produced by Bacillus subtilis HSO 121.	2008 Jul	18265435
Identification of food-derived bioactive peptides in blood and other biological samples.	2008 Jul-Aug	18727561
Evaluation of protective effects of Chi-Zhi-Huang decoction on Phase I drug metabolism of liver injured rats by cocktail probe drugs.	2008 May 22	18403144
Alcohol-induced decrease in muscle protein synthesis associated with increased binding of mTOR and raptor: Comparable effects in young and mature rats.	2009 Jan 20	19154606
High-throughput sequencing of peptoids and peptide-peptoid hybrids by partial edman degradation and mass spectrometry.	2009 Mar 9	19154119

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 00:36:51 GMT 2023` Edited by `admin` on `Sat Dec 16 00:36:51 GMT 2023`
Record UNII	0D58F84LSU
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PHENYL ISOTHIOCYANATE

Systematic Name

English

PHENYLISOTHIOCYANATE

Systematic Name

English

BENZENE, ISOTHIOCYANATO-

Systematic Name

English

ISOTHIOCYANIC ACID, PHENYL ESTER

Common Name

English

PHENYL ISOTHIOCYANATE [MI]

Common Name

English

NSC-5583

Code

English

Code System Code Type Description

MERCK INDEX

m8678