SELENOCYSTEINE

First approved in 2004

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C3H7NO2Se
Molecular Weight	168.05
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

N[C@@H](C[SeH])C(O)=O

InChI

InChIKey=ZKZBPNGNEQAJSX-REOHCLBHSA-N

InChI=1S/C3H7NO2Se/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C3H7NO2Se
Molecular Weight	168.05
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/24194593 | http://www.nutrientsreview.com/proteins/amino-acids/selenocysteine.html

Selenocysteine is a naturally occurring amino acid. It is analog of cysteine where thiol (-SH) group is replaced by selenol (-SeH) group. 54 human proteins are known to contain selenocysteine. Among them are eukaryotic elongation factor, glucose-6-phosphate dehydrogenase, glutathione peroxidase, and others. Selenocysteine is contained in meat, fish, cheese, cereals, Brazil nut and walnuts.

Approval Year

PubMed

Title	Date	PubMed
Renal and hepatic ALA-D activity and selected oxidative stress parameters of rats exposed to inorganic mercury and organoselenium compounds.	2004-01	14630126
Selenium-containing compounds attenuate peroxynitrite-mediated NF-kappaB and AP-1 activation and interleukin-8 gene and protein expression in human leukocytes.	2003-11-01	14572605
Induction of glutathione-S-transferase mRNA levels by chemopreventive selenocysteine Se-conjugates.	2002-05-15	12034368
Nucleotide sequence and expression of the selenocysteine-containing polypeptide of formate dehydrogenase (formate-hydrogen-lyase-linked) from Escherichia coli.	1986-07	2941757

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:53:05 GMT 2025` Edited by `admin` on `Mon Mar 31 19:53:05 GMT 2025`
Record UNII	0CH9049VIS
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

SELENOCYSTEINE [MI]

Preferred Name

English

SELENOCYSTEINE

Systematic Name

English

3-SELENYL-L-ALANINE

Systematic Name

English

SELENIUM CYSTEINE

Systematic Name

English

L-SELENOCYSTEINE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C73539