URANYL NITRATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	2NO3.2O.U
Molecular Weight	394.0375
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[O--].[O--].[U+6].[O-][N+]([O-])=O.[O-][N+]([O-])=O

InChI

InChIKey=GGVVXLZQJGUJMP-UHFFFAOYSA-N

InChI=1S/2NO3.2O.U/c2*2-1(3)4;;;/q2*-1;2*-2;+6

HIDE SMILES / InChI

Molecular Formula	HO
Molecular Weight	17.0073
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	U
Molecular Weight	238.02891
Charge	6
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	NO3
Molecular Weight	62.0049
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www2.mst.dk/Udgiv/publications/2013/12/978-87-93026-82-7.pdf

There is no information related biological or pharmacological application of sodium diuranate. This is slightly soluble salts, which possesses some toxicity, that has been studied on rabbits

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596

PubMed

Title	Date	PubMed
Ghrelin protects against depleted uranium-induced apoptosis of MC3T3-E1 cells through oxidative stress-mediated p38-mitogen-activated protein kinase pathway.	2016-01-01	26529667
Low-concentration uranium enters the HepG2 cell nucleus rapidly and induces cell stress response.	2015-12-25	26362510
Metallothionein deficiency aggravates depleted uranium-induced nephrotoxicity.	2015-09-15	26148447
Uranium modifies or not behavior and antioxidant status in the hippocampus of rats exposed since birth.	2015-02	25743749
Molecular, cellular, and tissue impact of depleted uranium on xenobiotic-metabolizing enzymes.	2014-02	24146111
Increased urinary excretion of albumin, hemopexin, transferrin and VDBP correlates with chronic sensitization to gentamicin nephrotoxicity in rats.	2013-02-08	23261757
Cholesterol 7alpha-hydroxylase (CYP7A1) activity is modified after chronic ingestion of depleted uranium in the rat.	2010-05	20362056
Uranium induces apoptosis and is genotoxic to normal rat kidney (NRK-52E) proximal cells.	2007-08	17522072
Calcium-binding proteins annexin A2 and S100A6 are sensors of tubular injury and recovery in acute renal failure.	2005-12	16316344
Pathological and biochemical modifications of renal function in ibuprofen-induced interstitial nephritis.	1996-01	8820499
Inhibition of HIV-1 proteinase by metal ions.	1992-06	1612181

Patents

Sample Use Guides

In Vivo Use Guide

toxic effect in rabbits: 4-hour exposures to uranium compounds using a lanolin vehicle showed that water-soluble compounds (uranyl fluoride, uranium tetrachloride, uranium pentachloride) were the most toxic; the slightly soluble compounds (uranium trioxide, sodium diuranate, ammonium diuranate) were less toxic, and the water insoluble compounds (uranium tetrafluoride, uranium dioxide, uranium peroxide, uriuranium octoxide) caused no deaths.

Route of Administration: Topical

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:35:29 GMT 2025` Edited by `admin` on `Mon Mar 31 18:35:29 GMT 2025`
Record UNII	0C0WI17JYF
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

URANIUM NITRATE OXIDE (UO2(NO3)2)

Preferred Name

English

URANYL NITRATE

Common Name

English

URANYL NITRATE [MI]

Common Name

English

URANIUM, BIS(NITRATO-.KAPPA.O)DIOXO-, (T-4)-

Systematic Name

English

URANYL DINITRATE

Common Name

English

URANIUM, DINITRATODIOXO-

Common Name

English

URANYL NITRATE (UO2(NO3)2)

Common Name

English

Code System Code Type Description

HSDB

1018