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Details

Stereochemistry ACHIRAL
Molecular Formula 2NO3.2O.U
Molecular Weight 394.0375
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of URANYL NITRATE

SMILES

[O--].[O--].[U+6].[O-][N+]([O-])=O.[O-][N+]([O-])=O

InChI

InChIKey=GGVVXLZQJGUJMP-UHFFFAOYSA-N
InChI=1S/2NO3.2O.U/c2*2-1(3)4;;;/q2*-1;2*-2;+6

HIDE SMILES / InChI
Molecular Formula NO3
Molecular Weight 62.0049
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula U
Molecular Weight 238.0289
Charge 6
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

There is no information related biological or pharmacological application of sodium diuranate. This is slightly soluble salts, which possesses some toxicity, that has been studied on rabbits

Approval Year

Unknown
139594
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Inhibition of HIV-1 proteinase by metal ions.
1992 Jun
Pathological and biochemical modifications of renal function in ibuprofen-induced interstitial nephritis.
1996 Jan
Calcium-binding proteins annexin A2 and S100A6 are sensors of tubular injury and recovery in acute renal failure.
2005 Dec
Uranium induces apoptosis and is genotoxic to normal rat kidney (NRK-52E) proximal cells.
2007 Aug
Cholesterol 7alpha-hydroxylase (CYP7A1) activity is modified after chronic ingestion of depleted uranium in the rat.
2010 May
Increased urinary excretion of albumin, hemopexin, transferrin and VDBP correlates with chronic sensitization to gentamicin nephrotoxicity in rats.
2013 Feb 8
Molecular, cellular, and tissue impact of depleted uranium on xenobiotic-metabolizing enzymes.
2014 Feb
Low-concentration uranium enters the HepG2 cell nucleus rapidly and induces cell stress response.
2015 Dec 25
Uranium modifies or not behavior and antioxidant status in the hippocampus of rats exposed since birth.
2015 Feb
Metallothionein deficiency aggravates depleted uranium-induced nephrotoxicity.
2015 Sep 15
Ghrelin protects against depleted uranium-induced apoptosis of MC3T3-E1 cells through oxidative stress-mediated p38-mitogen-activated protein kinase pathway.
2016 Jan 1
Patents

Patents

20090104111
12
7666387
12
US3156525
9
US3168370
9

Sample Use Guides

In Vivo Use Guide
toxic effect in rabbits: 4-hour exposures to uranium compounds using a lanolin vehicle showed that water-soluble compounds (uranyl fluoride, uranium tetrachloride, uranium pentachloride) were the most toxic; the slightly soluble compounds (uranium trioxide, sodium diuranate, ammonium diuranate) were less toxic, and the water insoluble compounds (uranium tetrafluoride, uranium dioxide, uranium peroxide, uriuranium octoxide) caused no deaths.
Route of Administration: Topical
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:44:41 GMT 2023
Edited
by admin
on Fri Dec 15 16:44:41 GMT 2023
Record UNII
0C0WI17JYF
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
URANYL NITRATE
MI  
Common Name English
URANYL NITRATE [MI]
Common Name English
URANIUM, BIS(NITRATO-.KAPPA.O)DIOXO-, (T-4)-
Systematic Name English
URANYL DINITRATE
Common Name English
URANIUM NITRATE OXIDE (UO2(NO3)2)
Common Name English
URANIUM, DINITRATODIOXO-
Common Name English
URANYL NITRATE (UO2(NO3)2)
Common Name English
Code System Code Type Description
HSDB
1018
Created by admin on Fri Dec 15 16:44:41 GMT 2023 , Edited by admin on Fri Dec 15 16:44:41 GMT 2023
PRIMARY
EPA CompTox
DTXSID6091556
Created by admin on Fri Dec 15 16:44:41 GMT 2023 , Edited by admin on Fri Dec 15 16:44:41 GMT 2023
PRIMARY
MESH
D014502
Created by admin on Fri Dec 15 16:44:42 GMT 2023 , Edited by admin on Fri Dec 15 16:44:42 GMT 2023
PRIMARY
RXCUI
1858851
Created by admin on Fri Dec 15 16:44:42 GMT 2023 , Edited by admin on Fri Dec 15 16:44:42 GMT 2023
PRIMARY
MERCK INDEX
m11318
Created by admin on Fri Dec 15 16:44:41 GMT 2023 , Edited by admin on Fri Dec 15 16:44:41 GMT 2023
PRIMARY Merck Index
CAS
36478-76-9
Created by admin on Fri Dec 15 16:44:41 GMT 2023 , Edited by admin on Fri Dec 15 16:44:41 GMT 2023
ALTERNATIVE
WIKIPEDIA
URANYL NITRATE
Created by admin on Fri Dec 15 16:44:42 GMT 2023 , Edited by admin on Fri Dec 15 16:44:42 GMT 2023
PRIMARY
ECHA (EC/EINECS)
233-266-3
Created by admin on Fri Dec 15 16:44:41 GMT 2023 , Edited by admin on Fri Dec 15 16:44:41 GMT 2023
PRIMARY
CAS
10102-06-4
Created by admin on Fri Dec 15 16:44:41 GMT 2023 , Edited by admin on Fri Dec 15 16:44:41 GMT 2023
PRIMARY
ECHA (EC/EINECS)
253-053-9
Created by admin on Fri Dec 15 16:44:41 GMT 2023 , Edited by admin on Fri Dec 15 16:44:41 GMT 2023
ALTERNATIVE
FDA UNII
0C0WI17JYF
Created by admin on Fri Dec 15 16:44:41 GMT 2023 , Edited by admin on Fri Dec 15 16:44:41 GMT 2023
PRIMARY
Related Record Type Details
Structure of URANIUM CATION (6+)
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of URANIUM CATION (6+)
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