PEGARGIMINASE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 22:28:26 GMT 2025` Edited by `admin` on `Mon Mar 31 22:28:26 GMT 2025`
Protein Type	ENZYME
Protein Sub Type
Sequence Origin	BACTERIAL
Sequence Type	COMPLETE
Record UNII	0B7PYQ9YRT
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

PEGARGIMINASE

Official Name

English

0B7PYQ9YRT

Preferred Name

English

ADI-SS

Code

English

pegargiminase [INN]

Common Name

English

ADIPEG20

Code

English

PEGARGIMINASE [USAN]

Common Name

English

ADI-PEG20

Code

English

ADI-PEG

Code

English

PENTAKIS(N-(4-(.OMEGA.-METHOXYPOLY(OXYETHYLENE))-4-OXOBUTANOYL))-(111-GLUTAMIC ACID,209-SERINE)ARGININE DEIMINASE (ADI, ARGININE DIHYDROLASE, AD) FROM MYCOPLASMA HOMINIS

Systematic Name

English

ADI-PEG 20

Code

English

PEGYLATED ARGININE DEIMINASE

Common Name

English

ADI-PEG-20

Code

English

ADI-PEG20 ARGININE DEIMINASE

Common Name

English

Pegargiminase [WHO-DD]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

437014

Created by admin on Mon Mar 31 22:28:26 GMT 2025 , Edited by admin on Mon Mar 31 22:28:26 GMT 2025

FDA ORPHAN DRUG

118398

Created by admin on Mon Mar 31 22:28:26 GMT 2025 , Edited by admin on Mon Mar 31 22:28:26 GMT 2025

FDA ORPHAN DRUG

120898

Created by admin on Mon Mar 31 22:28:26 GMT 2025 , Edited by admin on Mon Mar 31 22:28:26 GMT 2025

EU-Orphan Drug

EU/3/14/1409

Created by admin on Mon Mar 31 22:28:26 GMT 2025 , Edited by admin on Mon Mar 31 22:28:26 GMT 2025

NCI_THESAURUS

C29726

Created by admin on Mon Mar 31 22:28:26 GMT 2025 , Edited by admin on Mon Mar 31 22:28:26 GMT 2025

Code System Code Type Description

FDA UNII

0B7PYQ9YRT

Created by admin on Mon Mar 31 22:28:26 GMT 2025 , Edited by admin on Mon Mar 31 22:28:26 GMT 2025

PRIMARY

SMS_ID

100000182376

Created by admin on Mon Mar 31 22:28:26 GMT 2025 , Edited by admin on Mon Mar 31 22:28:26 GMT 2025

PRIMARY

ChEMBL

CHEMBL3137346

Created by admin on Mon Mar 31 22:28:26 GMT 2025 , Edited by admin on Mon Mar 31 22:28:26 GMT 2025

PRIMARY

USAN

AB-41

Created by admin on Mon Mar 31 22:28:26 GMT 2025 , Edited by admin on Mon Mar 31 22:28:26 GMT 2025

PRIMARY

DRUG BANK

DB06592

Created by admin on Mon Mar 31 22:28:26 GMT 2025 , Edited by admin on Mon Mar 31 22:28:26 GMT 2025

PRIMARY

CAS

1394129-74-8

Created by admin on Mon Mar 31 22:28:26 GMT 2025 , Edited by admin on Mon Mar 31 22:28:26 GMT 2025

PRIMARY

NCI_THESAURUS

C91702

Created by admin on Mon Mar 31 22:28:26 GMT 2025 , Edited by admin on Mon Mar 31 22:28:26 GMT 2025

PRIMARY

INN

9906

Created by admin on Mon Mar 31 22:28:26 GMT 2025 , Edited by admin on Mon Mar 31 22:28:26 GMT 2025

PRIMARY

Related Record Type Details


					94ZLA3W45F

ARGININE

TARGET -> SUBSTRATE

Amount:

Related Record Type Details


					0B7PYQ9YRT

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_6] [1_55] [1_62] [1_65] [1_87] [1_90] [1_110] [1_120] [1_135] [1_194] [1_197] [1_207] [1_241] [1_244] [1_247] [1_252] [1_261] [1_277] [1_279] [1_291] [1_315] [1_323] [1_355] [1_367] [1_373] [1_404] [1_407]		Lys	Amount:	M-PEG-20000 N6-SUCCINYLAMIDE-LYSINE	PAE5985ESA
AMINO_ACID_SUBSTITUTION	[1_1]		Ser	Amount:	M-PEG-20000 N-SUCCINYLAMIDE-SERINE	82B7L6YL68

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL