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Details

Stereochemistry ABSOLUTE
Molecular Formula C13H9F2NO4
Molecular Weight 281.2117
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LEVOFLOXACIN Q-ACID

SMILES

C[C@H]1COC2=C(F)C(F)=CC3=C2N1C=C(C(O)=O)C3=O

InChI

InChIKey=NVKWWNNJFKZNJO-YFKPBYRVSA-N
InChI=1S/C13H9F2NO4/c1-5-4-20-12-9(15)8(14)2-6-10(12)16(5)3-7(11(6)17)13(18)19/h2-3,5H,4H2,1H3,(H,18,19)/t5-/m0/s1

HIDE SMILES / InChI
Molecular Formula C13H9F2NO4
Molecular Weight 281.2117
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Levofloxacin Q-acid is an intermediate of Levofloxacin, - an inhibitor of bacterial DNA gyrase and topoisomerase IV with a minimum inhibitory concentration (MIC) of 0.75 ug/mL against penicillin-resistant Streptococcus pneumoniae.

Approval Year

Unknown
149124
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Syntheses of quinolone hydrochloride enantiomers from synthons (R)- and (S)-2-methylpiperazine.
2005-04-01
Patents

Patents

07189847
2
EP0368410
1
US20070244318
1
WO2006048889A1
1

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:18:34 GMT 2025
Edited
by admin
on Mon Mar 31 18:18:34 GMT 2025
Record UNII
08GT8FY84E
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LEVOFLOXACIN RELATED COMPOUND B
USP   USP-RS  
Preferred Name English
LEVOFLOXACIN Q-ACID
Common Name English
LEVOFLOXACIN HEMIHYDRATE IMPURITY F [EP IMPURITY]
Common Name English
LEVOFLOXACIN RELATED COMPOUND B [USP-RS]
Common Name English
(S)-(-)-9,10-DIFLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-7H-PYRIDO(1,2,3-DE)(1,4)BENZOXAZINE-6-CARBOXYLIC ACID
Systematic Name English
7H-PYRIDO(1,2,3-DE)-1,4-BENZOXAZINE-6-CARBOXYLIC ACID, 9,10-DIFLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-, (3S)-
Systematic Name English
LEVOFLOXACIN RELATED COMPOUND B [USP IMPURITY]
Common Name English
(S)-9,10-DIFLUORO-3-METHYL-7-OXO-2,3-DIHYDRO-7H-PYRIDO(1,2,3-DE)(1,4)BENZOXAZINE-6-CARBOXYLIC ACID
Systematic Name English
LEVOFLOXACIN Q-ACID, (-)-
Common Name English
Code System Code Type Description
RS_ITEM_NUM
1362125
Created by admin on Mon Mar 31 18:18:34 GMT 2025 , Edited by admin on Mon Mar 31 18:18:34 GMT 2025
PRIMARY
EPA CompTox
DTXSID60143604
Created by admin on Mon Mar 31 18:18:34 GMT 2025 , Edited by admin on Mon Mar 31 18:18:34 GMT 2025
PRIMARY
FDA UNII
08GT8FY84E
Created by admin on Mon Mar 31 18:18:34 GMT 2025 , Edited by admin on Mon Mar 31 18:18:34 GMT 2025
PRIMARY
PUBCHEM
688333
Created by admin on Mon Mar 31 18:18:34 GMT 2025 , Edited by admin on Mon Mar 31 18:18:34 GMT 2025
PRIMARY
CAS
100986-89-8
Created by admin on Mon Mar 31 18:18:34 GMT 2025 , Edited by admin on Mon Mar 31 18:18:34 GMT 2025
PRIMARY
Related Record Type Details
Structure of LEVOFLOXACIN
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of LEVOFLOXACIN
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
NIH
NCATS
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