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Details

Stereochemistry ACHIRAL
Molecular Formula C21H19N3O4S
Molecular Weight 409.458
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of J-30

SMILES

COC1=CC=C(C=C1)S(=O)(=O)N2CCC3=C2C(NC(=O)C4=CC=NC=C4)=CC=C3

InChI

InChIKey=QGWOKAXBIMWTNE-UHFFFAOYSA-N
InChI=1S/C21H19N3O4S/c1-28-17-5-7-18(8-6-17)29(26,27)24-14-11-15-3-2-4-19(20(15)24)23-21(25)16-9-12-22-13-10-16/h2-10,12-13H,11,14H2,1H3,(H,23,25)

HIDE SMILES / InChI

Molecular Formula C21H19N3O4S
Molecular Weight 409.458
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
A novel oral indoline-sulfonamide agent, N-[1-(4-methoxybenzenesulfonyl)-2,3-dihydro-1H-indol-7-yl]-isonicotinamide (J30), exhibits potent activity against human cancer cells in vitro and in vivo through the disruption of microtubule.
2007-10
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 22:50:45 GMT 2025
Edited
by admin
on Mon Mar 31 22:50:45 GMT 2025
Record UNII
0896Z9T2XN
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
4-PYRIDINECARBOXAMIDE, N-(2,3-DIHYDRO-1-((4-METHOXYPHENYL)SULFONYL)-1H-INDOL-7-YL)-
Preferred Name English
J-30
Common Name English
N-(1-(4-METHOXYPHENYLSULFONYL)-2,3-DIHYDRO-1H-INDOL-7-YL)ISONICOTINAMIDE
Systematic Name English
Code System Code Type Description
PUBCHEM
16215971
Created by admin on Mon Mar 31 22:50:45 GMT 2025 , Edited by admin on Mon Mar 31 22:50:45 GMT 2025
PRIMARY
FDA UNII
0896Z9T2XN
Created by admin on Mon Mar 31 22:50:45 GMT 2025 , Edited by admin on Mon Mar 31 22:50:45 GMT 2025
PRIMARY
CAS
916484-16-7
Created by admin on Mon Mar 31 22:50:45 GMT 2025 , Edited by admin on Mon Mar 31 22:50:45 GMT 2025
PRIMARY
Related Record Type Details
ACTIVE MOIETY