SUCROSE OCTAACETATE

US Previously Marketed

First approved in 2015

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C28H38O19
Molecular Weight	678.5899
Optical Activity	UNSPECIFIED
Defined Stereocenters	9 / 9
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(=O)OC[C@H]1O[C@@](COC(C)=O)(O[C@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]2OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O

InChI

InChIKey=ZIJKGAXBCRWEOL-SAXBRCJISA-N

InChI=1S/C28H38O19/c1-12(29)37-9-20-22(40-15(4)32)24(42-17(6)34)25(43-18(7)35)27(45-20)47-28(11-39-14(3)31)26(44-19(8)36)23(41-16(5)33)21(46-28)10-38-13(2)30/h20-27H,9-11H2,1-8H3/t20-,21-,22-,23-,24+,25-,26+,27-,28+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C28H38O19
Molecular Weight	678.5899
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	9 / 9
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: http://www.deyerchem.com/products_detail_e/id/26.html

Sucrose octaacetate is an acetylated derivative of sucrose. It can be used as a bitter additive, a denaturant for alcohol, a soaker for paper, as well as an insecticide, plasticizer for cellulosic&synthetic resin. It also can be used as an additive for paint and children's toys, etc. It can prevent mice or children from biting or tasting the goods because of its extreme bitter taste. Sucrose octaacetate was determined by the EPA to be usable as an inert ingredient in pesticides due to its low toxicity

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596

Sourcing

Vendor/Aggregator	ID	URL
3B Scientific (Wuhan) Corp	3B3-001729	http://www.3bsc.com/index/pro_info.php?id=23620
AA Blocks	AA000QLH	https://www.aablocks.com/goods/Goods/detail?id=AA000QLH
Aaron Chemicals	AR000RD9	http://www.aaronchem.com/126-14-7
abcr GmbH	AB141533	http://www.abcr.com/shop/en/AB141533
Achemo Scientific Limited	AC-10129	http://www.achemo.com/product_view.asp?ID=20
Achemtek	0104-017764	http://www.achemtek.com/126-14-7
Acorn PharmaTech	ACN-040007	http://www.acornpharmatech.com/
Acros Organics	AC419790010	https://www.fishersci.com/shop/products/sucrose-octaacetate-98-acros-organics/AC419790010
Acros Organics	AC419790051	https://www.fishersci.com/shop/products/sucrose-octaacetate-98-acros-organics-3/AC419790051
Acros Organics	AC419792500	https://www.fishersci.com/shop/products/sucrose-octaacetate-98-acros-organics/AC419792500
AHH Chemical co.,ltd	MT-58822	http://www.ahhchemical.com/product/MT-58822.html
AK Scientific, Inc. (AKSCI)	P669	http://www.aksci.com/item_detail.php?cat=P669
Alfa Chemistry	AP126147-A	https://reagents.alfa-chemistry.com/product/d-sucrose-octaacetate-cas-126-14-7-3362.html
Alfa Chemistry	AP126147-B	https://reagents.alfa-chemistry.com/product/sucrose-octaacetate-cas-126-14-7-3363.html
Alichem	490012263	http://www.alichem.com/en/products/126-14-7.html
Ambeed	A813260	https://www.ambeed.com/products/126-14-7.html
Aurora Fine Chemicals LLC	A13.111.609	http://online.aurorafinechemicals.com/info?ID=A13.111.609
Avantor Inc	200038-830	https://us.vwr.com/store/product/7520962/d-sucrose-octaacetate-98
Avantor Inc	EM8.22144.0250	https://us.vwr.com/store/product/15143054/d-sucrose-octaacetate-for-synthesis
BioSynth	Q-201753	https://www.biosynth.com/en/products/life-science/other-biochemicals/products/Q-201753.html
BLD Pharm	BD152100	http://www.bldpharm.com/products/126-14-7.html
Boerchem	BC221791	http://www.boerchem.com/?product_37464.html
Chem Scene	CS-0066987	http://www.chemscene.com/126-14-7.html
Chemenu	CM100834	http://www.chemenu.com/products/CM100834
ChemMol	44006636	http://www.chemmol.com/chemmol/44006636.html
ChemMol	49415750	http://www.chemmol.com/chemmol/49415750.html
Chemspace	CSSB00016990608	https://chem-space.com/CSSB00016990608
eNovation Chemicals	D915864	https://www.enovationchem.com/ProductDetails.asp?ProductID=D915864
eNovation Chemicals	Y1040676	https://www.enovationchem.com/ProductDetails.asp?ProductID=Y1040676
Glentham Life Sciences	GC6190	http://www.glentham.com/products/product/GC6190/
Hairui	HR135293	http://www.hairuichem.com/en/product/126-14-7.html
Lab Network	LN00200533	https://labnetwork.com/frontend-app/p/#!/moleculedetails/LN00200533
Matrix Scientific	99013	https://www.matrixscientific.com/099013.html
MedChem Express	HY-119309	https://www.medchemexpress.com/sucrose-octaacetate.html
MuseChem	R041950	https://www.musechem.com/product/R041950.html
Parchem	11956	http://www.parchem.com/chemical-supplier-distributor/Sucrose-Octaacetate-001956.aspx
Parchem	20919	http://www.parchem.com/chemical-supplier-distributor/sucrose-octaacetate-010919.aspx
Sigma-Aldrich	1623615_USP	https://www.sigmaaldrich.com/catalog/product/usp/1623615?utm_source=pubchem&utm_campaign=pubchem_2017&utm_medium=referral
Sigma-Aldrich	252603_ALDRICH	https://www.sigmaaldrich.com/catalog/product/aldrich/252603?utm_source=pubchem&utm_campaign=pubchem_2017&utm_medium=referral
Sigma-Aldrich	94474_SIAL	https://www.sigmaaldrich.com/catalog/product/sial/94474?utm_source=pubchem&utm_campaign=pubchem_2017&utm_medium=referral
Sigma-Aldrich	W303801_ALDRICH	https://www.sigmaaldrich.com/catalog/product/aldrich/w303801?utm_source=pubchem&utm_campaign=pubchem_2017&utm_medium=referral
Smolecule	S544079	http://www.smolecule.com/products/s544079
TCI (Tokyo Chemical Industry)	S0052	http://www.tcichemicals.com/eshop/en/us/commodity/S0052/index.html
THE BioTek	bt-285190	https://www.thebiotek.com/product/inhibitors/bt-285190
VladaChem	VL272584-1KG	https://www.vladachem.com/product.php?products=126-14-7
Yuhao Chemical	HL1518	http://www.chemyuhao.com/126-14-7.html

PubMed

Title	Date	PubMed
The perception of quinine taste intensity is associated with common genetic variants in a bitter receptor cluster on chromosome 12.	2010-11-01	20675712
Gustatory responsiveness to six bitter tastants in three species of nonhuman primates.	2009-05	19399556
Electron spin-lattice relaxation of nitroxyl radicals in temperature ranges that span glassy solutions to low-viscosity liquids.	2008-03	18166493
Analysis of axonal regeneration in the central and peripheral nervous systems of the NG2-deficient mouse.	2007-09-27	17900358
Behavioral genetics and taste.	2007-09-18	17903279
Photoinduced electron transfer in arylacridinium conjugates in a solid glass matrix.	2007-06-21	17539680
Rapid quantification of sucrose esters in oriental tobacco by liquid chromatography-ion trap mass spectrometry.	2007-01	17313139
Examination of glass transitions in CO(2)-processed, peracetylated sugars using sum frequency generation spectroscopy.	2006-08-15	16893233
Heritability and genetic covariation of sensitivity to PROP, SOA, quinine HCl, and caffeine.	2006-06	16527870
Deposition of small organic molecules by the displacement of two immiscible supercritical phases.	2006-02-28	16489797
Ultrathin film deposition by liquid CO2 free meniscus coating-uniformity and morphology.	2006-01-17	16401113
Bitterness suppression with zinc sulfate and na-cyclamate: a model of combined peripheral and central neural approaches to flavor modification.	2005-11	16132352
High resolution 1H NMR structural studies of sucrose octaacetate in supercritical carbon dioxide.	2005-10-21	16078290
Inbred mouse strains C57BL/6J and DBA/2J vary in sensitivity to a subset of bitter stimuli.	2005-06-20	15967025
Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice.	2005-06-06	15938754
Enhanced photoluminescence from group 14 metalloles in aggregated and solid solutions.	2005-03-21	15762727
The contribution of taste bud populations to bitter avoidance in mouse strains differentially sensitive to sucrose octa-acetate and quinine.	2004-11	15574813
Biochemical enrichment and biophysical characterization of a taste receptor for L-arginine from the catfish, Ictalurus puntatus.	2004-07-28	15282034
Variation in intake of sweet and bitter solutions by inbred strains of golden hamsters.	2004-07	15082943
The distinctiveness of ionic and nonionic bitter stimuli.	2004-01	14741226
A psychophysical investigation of binary bitter-compound interactions.	2003-05	12771017
Comparison of the responses of the chorda tympani and glossopharyngeal nerves to taste stimuli in C57BL/6J mice.	2003-03-04	12617752
Conditioned acceptance and preference but not altered taste reactivity responses to bitter and sour flavors paired with intragastric glucose infusion.	2003-02	12576114
A brief-access test for bitter taste in mice.	2002-02	11839611
High-resolution genetic mapping of the sucrose octaacetate taste aversion (Soa) locus on mouse Chromosome 6.	2001-09	11641717
Covariation in individuals' sensitivities to bitter compounds: evidence supporting multiple receptor/transduction mechanisms.	2001-07	11521845
Effect of compound sequence on bitterness enhancement.	2001-05	11369676
Soa genotype selectively affects mouse gustatory neural responses to sucrose octaacetate.	2001-04-27	11328963
Taste receptor cells that discriminate between bitter stimuli.	2001-02-23	11222863
Reduction of saltiness and bitterness after a chlorhexidine rinse.	2001-02	11238242
Behavioral specificity of the bitter taste gene Soa.	1997-12-31	9402622

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:26:21 GMT 2025` Edited by `admin` on `Mon Mar 31 21:26:21 GMT 2025`
Record UNII	07V591057T
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SUCROSE OCTA-ACETATE

Preferred Name

English

SUCROSE OCTAACETATE

Official Name

English

SUCROSE OCTAACETATE [FHFI]

Common Name

English

FEMA NO. 3038

Code

English

.ALPHA.-D-GLUCOPYRANOSIDE, 1,3,4,6-TETRA-O-ACETYL-.BETA.-D-FRUCTOFURANOSYL, TETRAACETATE

Common Name

English

SUCROSE OCTA-ACETATE [MART.]

Common Name

English

SUCROSE OCTAACETATE [USP-RS]

Common Name

English

Sucrose octa-acetate [WHO-DD]

Common Name

English

SUCROSE OCTAACETATE [MI]

Common Name

English

NSC-1695

Code

English

Classification Tree Code System Code

CFR

21 CFR 310.536