PORGAVIXIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 11:19:26 GMT 2023` Edited by `admin` on `Sat Dec 16 11:19:26 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	MOUSE CHIMERIC
Sequence Type	COMPLETE
Record UNII	07EY0HWO2M
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PORGAVIXIMAB

Official Name

English

porgaviximab [INN]

Common Name

English

2G4

Common Name

English

ZMAP COMPONENT C2G4

Common Name

English

IMMUNOGLOBULIN G1-KAPPA, ANTI-(EBOLAVIRUS GLYCOPROTEIN) CHIMERIC HOMO SAPIENS-MUS MUSCULUS MONOCLONAL ANTIBODY: .GAMMA.1 HEAVY CHAIN (1-451) (MUS MUSCULUS VH (IGHV6-6*02 (95%) (IGHD)-IGHJ4*01 (94%)) (8.10.12) (1-121) -HOMO SAPIENS IGHG1*01(CH1 K97>R(218)

Systematic Name

English

IMMUNOGLOBULIN G1, ANTI-(EBOLAVIRUS GLYCOPROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL C2G4 HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL C2G4 .KAPPA.-CHAIN, DIMER

Systematic Name

English

C2G4

Code

English

PORGAVIXIMAB [USAN]

Common Name

English

ZMAPP COMPONENT C2G4

Common Name

English

Porgaviximab [WHO-DD]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

440914

Created by admin on Sat Dec 16 11:19:26 GMT 2023 , Edited by admin on Sat Dec 16 11:19:26 GMT 2023

Code System Code Type Description

FDA UNII

07EY0HWO2M

Created by admin on Sat Dec 16 11:19:26 GMT 2023 , Edited by admin on Sat Dec 16 11:19:26 GMT 2023

PRIMARY

INN

10536

Created by admin on Sat Dec 16 11:19:26 GMT 2023 , Edited by admin on Sat Dec 16 11:19:26 GMT 2023

PRIMARY

USAN

DE-20

Created by admin on Sat Dec 16 11:19:26 GMT 2023 , Edited by admin on Sat Dec 16 11:19:26 GMT 2023

PRIMARY

CAS

1792982-55-8

Created by admin on Sat Dec 16 11:19:26 GMT 2023 , Edited by admin on Sat Dec 16 11:19:26 GMT 2023

PRIMARY

NCI_THESAURUS

C175195

Created by admin on Sat Dec 16 11:19:26 GMT 2023 , Edited by admin on Sat Dec 16 11:19:26 GMT 2023

PRIMARY

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_301
N	2_301

Related Record Type Details


					XH5V2SQ5FI

ZAIRE EBOLAVIRUS STRAIN KIKWIT-95 ENVELOPE GLYCOPROTEIN

TARGET -> INHIBITOR


					3R8G5WNW24

ZAIRE EBOLAVIRUS

TARGET ORGANISM->INHIBITOR

Comments:

Directly neutralizes virus in-vitro.

Related Record Type Details


					07EY0HWO2M

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL