BIVATUZUMAB MERTANSINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 07:50:20 GMT 2025` Edited by `admin` on `Wed Apr 02 07:50:20 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	INCOMPLETE
Record UNII	074GT4PR9D
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BIWA-4 MERTANSINE

Preferred Name

English

BIVATUZUMAB MERTANSINE

Official Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN CD44V6 (ANTIGEN)) (HUMAN-MOUSE MONOCLONAL BIWA4 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL BIWA4 .KAPPA.-CHAIN, DIMER, MERTANSINE CONJUGATE

Systematic Name

English

Code System Code Type Description

CAS

936332-86-4

Created by admin on Wed Apr 02 07:50:20 GMT 2025 , Edited by admin on Wed Apr 02 07:50:20 GMT 2025

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FDA UNII

074GT4PR9D

Created by admin on Wed Apr 02 07:50:20 GMT 2025 , Edited by admin on Wed Apr 02 07:50:20 GMT 2025

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INN

7965

Created by admin on Wed Apr 02 07:50:20 GMT 2025 , Edited by admin on Wed Apr 02 07:50:20 GMT 2025

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EVMPD

SUB20327

Created by admin on Wed Apr 02 07:50:20 GMT 2025 , Edited by admin on Wed Apr 02 07:50:20 GMT 2025

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SMS_ID

100000175008

Created by admin on Wed Apr 02 07:50:20 GMT 2025 , Edited by admin on Wed Apr 02 07:50:20 GMT 2025

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ChEMBL

CHEMBL2108413

Created by admin on Wed Apr 02 07:50:20 GMT 2025 , Edited by admin on Wed Apr 02 07:50:20 GMT 2025

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Related Record Type Details


					7KI95LX9LZ

TARGET->LIGAND

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION					CYSTEINYL-MERTANSINE	R4N2PA8764

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL