Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C8H6S |
| Molecular Weight | 134.198 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
S1C=CC2=C1C=CC=C2
InChI
InChIKey=FCEHBMOGCRZNNI-UHFFFAOYSA-N
InChI=1S/C8H6S/c1-2-4-8-7(3-1)5-6-9-8/h1-6H
| Molecular Formula | C8H6S |
| Molecular Weight | 134.198 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Synthesis and biological activity of alpha-bromoacryloyl lexitropsin conjugates. | 2005-11 |
|
| Biodesulfurization of dibenzothiophene and other organic sulfur compounds by a newly isolated Microbacterium strain ZD-M2. | 2005-06-01 |
|
| Prediction of genotoxicity of chemical compounds by statistical learning methods. | 2005-06 |
|
| Hydroxylation activity of P450 BM-3 mutant F87V towards aromatic compounds and its application to the synthesis of hydroquinone derivatives from phenolic compounds. | 2005-06 |
|
| Triplet-triplet energy transfer controlled by the donor-acceptor distance in rigidly held palladium-containing cofacial bisporphyrins. | 2005-05-20 |
|
| Selective adsorption of thiophene and 1-benzothiophene on metal-ion-exchanged zeolites in organic medium. | 2005-05-15 |
|
| Efficient access to 2-aryl-3-substituted benzo[b]thiophenes. | 2005-04-29 |
|
| Synthesis and binding affinities of novel SRIF-mimicking beta-D-glucosides satisfying the requirement for a pi-cloud at C1. | 2005-03-17 |
|
| Poly(thiaheterohelicene): a stiff conjugated helical polymer comprised of fused benzothiophene rings. | 2005-03-03 |
|
| Benzothiophenes containing a piperazine side chain as selective ligands for the estrogen receptor alpha and their bioactivities in vivo. | 2005-03-01 |
|
| Desulfurization of dibenzothiophene, benzothiophene, and other thiophene analogs by a newly isolated bacterium, Gordonia alkanivorans strain 1B. | 2005-03 |
|
| In vitro metabolic fate of a novel structural class: evidence for the formation of a reactive intermediate on a benzothiophene moiety. | 2005-02-28 |
|
| Benzo[b]thiophenesulphonamide 1,1-dioxide derivatives inhibit tNOX activity in a redox state-dependent manner. | 2005-02-28 |
|
| Design, synthesis, and biological evaluation of novel potent and selective alphavbeta3/alphavbeta5 integrin dual inhibitors with improved bioavailability. Selection of the molecular core. | 2005-02-24 |
|
| Simultaneous determination of NSO-heterocycles, homocycles and their metabolites in groundwater of tar oil contaminated sites using LC with diode array UV and fluorescence detection. | 2005-02-18 |
|
| Organoboron compounds with an 8-hydroxyquinolato chelate and its derivatives: substituent effects on structures and luminescence. | 2005-02-07 |
|
| Thermophilic biodesulfurization of various heterocyclic sulfur compounds and crude straight-run light gas oil fraction by a newly isolated strain Mycobacterium phlei WU-0103. | 2005-02 |
|
| Endocrinology and hormone therapy in breast cancer: selective oestrogen receptor modulators and downregulators for breast cancer - have they lost their way? | 2005 |
|
| Adsorption, desorption, and conversion of thiophene on H-ZSM5. | 2004-12-07 |
|
| Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: a structure-activity evaluation study. | 2004-12-06 |
|
| Synthesis and NMR spectroscopic studies of allylsulfanyl-N1-alkyl-N4-phenyl-1,4-phenylenediamines and their cyclization products, 2,3-dihydro-1-benzothiophenes and thiochromans. | 2004-12 |
|
| NH2-SEP-PAK cartridges for enrichment of Aromatic Sulfur Compounds from sea water: determination by GC-FID and GC-MS. | 2004-10-28 |
|
| Palladium-catalyzed tandem reaction of yne-propargylic carbonates with boronic acids: a simple method for the synthesis of fused aromatic rings through allene-mediated electrocyclization. | 2004-10-25 |
|
| Benzothiophene and naphthalene derived constrained SERMs. | 2004-10-18 |
|
| New 3-[4-(2,3-dihydro-14-benzodioxin-5-yl)piperazin-1-yl]-1-(5-substituted benzo[b]thiophen-3-yl)propanol derivatives with dual action at 5-HT(1A) serotonin receptors and serotonin transporter as a new class of antidepressants. | 2004-07 |
|
| Phenylpiperazinylmethylheterocycle derivatives: synthesis and dopamine receptor binding profiles. | 2004-07 |
|
| C17,20-lyase inhibitors I. Structure-based de novo design and SAR study of C17,20-lyase inhibitors. | 2004-05-01 |
|
| [Determination of sulfur compounds in fluid catalytic cracking gasoline by gas chromatography with a sulfur chemiluminescence detector]. | 2004-05 |
|
| Synthesis and serotonergic activity of variously substituted (3-amido)phenylpiperazine derivatives and benzothiophene-4-piperazine derivatives: novel antagonists for the vascular 5-HT1B receptor. | 2004-04 |
|
| Design, synthesis and structure-activity relationship of novel RXR-selective modulators. | 2004-03-22 |
|
| Discovery of novel heteroaryl-substituted chalcones as inhibitors of TNF-alpha-induced VCAM-1 expression. | 2004-03-22 |
|
| Efficient isomer-pure synthesis of a benzo[b]thiophene analogue of pentacene. | 2004-03-19 |
|
| Synthesis and cytotoxic activity of lipophilic sulphonamide derivatives of the benzo[b]thiophene 1,1-dioxide. | 2004-03-01 |
|
| Synthesis of new thiophene and benzo[b]thiophene hydrazide derivatives as human NPY Y(5) antagonists. | 2004-02-09 |
|
| A synthesis of heteroaromatic analogues of 1-methyl-1,2,3,4-tetrahydroisoquinoline using the Pummerer-type cyclization reaction: observation of tandem cyclization reaction. | 2004-02 |
|
| Elimination of sulfur from aromatic heterocycles by a water-soluble arene ruthenium cluster: synthesis and molecular structure of [H2S2Ru4(C6H6)4]Cl2. | 2004-01-21 |
|
| Modulation of selective serotonin reuptake inhibitor and 5-HT1A antagonist activity in 8-aza-bicyclo[3.2.1]octane derivatives of 2,3-dihydro-1,4-benzodioxane. | 2004-01-19 |
|
| Combined application of stable carbon isotope analysis and specific metabolites determination for assessing in situ degradation of aromatic hydrocarbons in a tar oil-contaminated aquifer. | 2004-01-15 |
|
| Potent inhibition of human liver aldehyde oxidase by raloxifene. | 2004-01 |
|
| Monitoring toxicity of industrial wastewater and specific chemicals to a green alga, nitrifying bacteria and an aquatic bacterium. | 2004 |
|
| Advances in estrogen receptor biology: prospects for improvements in targeted breast cancer therapy. | 2004 |
|
| Structure-activity relationship of benzo[b]thiophene-2-sulfonamide derivatives as novel human chymase inhibitors. | 2003-11-17 |
|
| Reactions that generate aromatic molecules: is aromatic stabilization less or more advanced than bond changes at the transition state? Kinetic and thermodynamic acidities of rhenium carbene complexes. | 2003-10-08 |
|
| Nitrosation, nitration, and autoxidation of the selective estrogen receptor modulator raloxifene by nitric oxide, peroxynitrite, and reactive nitrogen/oxygen species. | 2003-10 |
|
| 2,6-disubstituted pyran-4-one and thiopyran-4-one inhibitors of DNA-Dependent protein kinase (DNA-PK). | 2003-09-15 |
|
| Synthesis and binding affinities of fluoroalkylated raloxifenes. | 2003-08-15 |
|
| Target specificity of selective estrogen receptor modulators within human endometrial cancer cells. | 2003-07 |
|
| Selective estrogen receptor modulators. | 2003-05 |
|
| Design, synthesis and in vitro evaluation of novel benzo[b]thiophene derivatives as serotonin N-acetyltransferase (AANAT) inhibitors. | 2003-04 |
|
| Advances in breast cancer treatment and prevention: preclinical studies on aromatase inhibitors and new selective estrogen receptor modulators (SERMs). | 2003 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:29:19 GMT 2025
by
admin
on
Mon Mar 31 19:29:19 GMT 2025
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| Record UNII |
073790YQ2G
|
| Record Status |
Validated (UNII)
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| Record Version |
|
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35858
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m10725
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7221
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202-395-7
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11095-43-5
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35857
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073790YQ2G
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C088015
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Benzothiophene
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DTXSID2052736
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47196
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