THIANAPHTHENE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H6S
Molecular Weight	134.198
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

S1C=CC2=C1C=CC=C2

InChI

InChIKey=FCEHBMOGCRZNNI-UHFFFAOYSA-N

InChI=1S/C8H6S/c1-2-4-8-7(3-1)5-6-9-8/h1-6H

HIDE SMILES / InChI

Molecular Formula	C8H6S
Molecular Weight	134.198
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Update on endocrine aspects of breast cancer: report from the 23rd San Antonio Breast Cancer Symposium, San Antonio, Texas, USA, 6-9 December 2000.	2001	11305952
Phase I study of a third-generation selective estrogen receptor modulator, LY353381.HCL, in metastatic breast cancer.	2001 Apr 1	11283133
Analysis of cross-resistance of the selective estrogen receptor modulators arzoxifene (LY353381) and LY117018 in tamoxifen-stimulated breast cancer xenografts.	2001 Aug	11489833
Raloxifene.	2001 Dec	11732640
Physical organic chemistry of transition metal carbene complexes. 23. Kinetic and thermodynamic acidities of cationic benzothienyl- and selenylcarbene complexes of rhenium in aqueous acetonitrile.	2001 Dec 5	11724595
Microbial desulfurization of alkylated dibenzothiophene and alkylated benzothiophene by recombinant Rhodococcus sp. strain T09.	2001 Jul	11499930
Electron transfer compatible molecular design of benzothiophene-acetophenone bichromophores: a theoretical approach.	2001 Mar 1	11300566
A novel palladium-mediated coupling approach to 2,3-disubstituted benzo(b)thiophenes and its application to the synthesis of tubulin binding agents.	2001 Mar 8	11259028
Desulfurization of benzothiophene by the Gram-negative bacterium, Sinorhizobium sp. KT55.	2001 Sep	11400068
Aerobic co-metabolism of sulfur, nitrogen and oxygen heterocycles by three marine bacterial consortia.	2002	11925758
Synthesis of fluoren-9-ones by the palladium-catalyzed cyclocarbonylation of o-halobiaryls.	2002 Aug 9	12153259
Cytochrome P450 3A4-mediated bioactivation of raloxifene: irreversible enzyme inhibition and thiol adduct formation.	2002 Jul	12119000
Purification and characterization of the monooxygenase catalyzing sulfur-atom specific oxidation of dibenzothiophene and benzothiophene from the thermophilic bacterium Paenibacillus sp. strain A11-2.	2002 Oct	12382053
4-Substituted D-glutamic acid analogues: the first potent inhibitors of glutamate racemase (MurI) enzyme with antibacterial activity.	2002 Sep 26	12238935
Photochemistry and photophysics of thienocarbazoles.	2003 Feb	12785049
Target specificity of selective estrogen receptor modulators within human endometrial cancer cells.	2003 Jul	12943742
Selective estrogen receptor modulators.	2003 May	12911186
The effect of minor-groove hydrogen-bond acceptors and donors on the stability and replication of four unnatural base pairs.	2003 May 21	12785844
Structure-activity relationship of benzo[b]thiophene-2-sulfonamide derivatives as novel human chymase inhibitors.	2003 Nov 17	14592513
Nitrosation, nitration, and autoxidation of the selective estrogen receptor modulator raloxifene by nitric oxide, peroxynitrite, and reactive nitrogen/oxygen species.	2003 Oct	14565768
Reactions that generate aromatic molecules: is aromatic stabilization less or more advanced than bond changes at the transition state? Kinetic and thermodynamic acidities of rhenium carbene complexes.	2003 Oct 8	14519018
Monitoring toxicity of industrial wastewater and specific chemicals to a green alga, nitrifying bacteria and an aquatic bacterium.	2004	15537017
Synthesis and NMR spectroscopic studies of allylsulfanyl-N1-alkyl-N4-phenyl-1,4-phenylenediamines and their cyclization products, 2,3-dihydro-1-benzothiophenes and thiochromans.	2004 Dec	15389922
Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: a structure-activity evaluation study.	2004 Dec 6	15501050
Combined application of stable carbon isotope analysis and specific metabolites determination for assessing in situ degradation of aromatic hydrocarbons in a tar oil-contaminated aquifer.	2004 Jan 15	14750740
Modulation of selective serotonin reuptake inhibitor and 5-HT1A antagonist activity in 8-aza-bicyclo[3.2.1]octane derivatives of 2,3-dihydro-1,4-benzodioxane.	2004 Jan 19	14698193
New 3-[4-(2,3-dihydro-14-benzodioxin-5-yl)piperazin-1-yl]-1-(5-substituted benzo[b]thiophen-3-yl)propanol derivatives with dual action at 5-HT(1A) serotonin receptors and serotonin transporter as a new class of antidepressants.	2004 Jul	15296084
Efficient isomer-pure synthesis of a benzo[b]thiophene analogue of pentacene.	2004 Mar 19	15058973
Palladium-catalyzed tandem reaction of yne-propargylic carbonates with boronic acids: a simple method for the synthesis of fused aromatic rings through allene-mediated electrocyclization.	2004 Oct 25	15378726
NH2-SEP-PAK cartridges for enrichment of Aromatic Sulfur Compounds from sea water: determination by GC-FID and GC-MS.	2004 Sep-Oct	15506625
Thermophilic biodesulfurization of various heterocyclic sulfur compounds and crude straight-run light gas oil fraction by a newly isolated strain Mycobacterium phlei WU-0103.	2005 Feb	15702256
Prediction of genotoxicity of chemical compounds by statistical learning methods.	2005 Jun	15962942
Hydroxylation activity of P450 BM-3 mutant F87V towards aromatic compounds and its application to the synthesis of hydroquinone derivatives from phenolic compounds.	2005 Jun	15549292
Benzothiophenes containing a piperazine side chain as selective ligands for the estrogen receptor alpha and their bioactivities in vivo.	2005 Mar 1	15713417
Synthesis and binding affinities of novel SRIF-mimicking beta-D-glucosides satisfying the requirement for a pi-cloud at C1.	2005 Mar 17	15760154

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:59:50 GMT 2023` Edited by `admin` on `Fri Dec 15 18:59:50 GMT 2023`
Record UNII	073790YQ2G
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

THIANAPHTHENE

Common Name

English

THIANAPHTHENE [MI]

Common Name

English

BENZOTHIOPHENE

Systematic Name

English

NSC-47196

Code

English

BENZOTHIOFURAN

Common Name

English

BENZO(B)THIOPHENE

Systematic Name

English

Code System Code Type Description

CHEBI

35858