2-CHLORODIAZEPAM

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H12Cl2N2O
Molecular Weight	319.185
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1C2=CC=C(Cl)C=C2C(=NCC1=O)C3=CC=CC=C3Cl

InChI

InChIKey=VPAYQWRBBOGGPY-UHFFFAOYSA-N

InChI=1S/C16H12Cl2N2O/c1-20-14-7-6-10(17)8-12(14)16(19-9-15(20)21)11-4-2-3-5-13(11)18/h2-8H,9H2,1H3

HIDE SMILES / InChI

Molecular Formula	C16H12Cl2N2O
Molecular Weight	319.185
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://dx.doi.org/10.1016/j.forsciint.2016.09.006
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/24604775

Dicazepam (known as Ro5-3448, chlorodiazepam and 2'-chloro-diazepam) is a 2’-chloro derivative of diazepam that has emerged as a designer drug and is intended for forensic and research applications. It is metabolized in vivo into the pharmacologically active which can be detected in urine.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
Characterization of the designer benzodiazepine diclazepam and preliminary data on its metabolism and pharmacokinetics.	2014 Jul-Aug	24604775

Patents

Sample Use Guides

In Vivo Use Guide

one tablet of diclazepam (declared amount: 1 mg) was ingested

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:58:36 GMT 2023` Edited by `admin` on `Fri Dec 15 17:58:36 GMT 2023`
Record UNII	070818R7PB
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2-CHLORODIAZEPAM

Common Name

English

1-METHYL-7-CHLORO-5-(2-CHLOROPHENYL)-1H-1,4-BENZODIAZEPINE-2(3H)-ONE

Systematic Name

English

DICLAZEPAM

Common Name

English

RO 5-3448

Code

English

CHLORODIAZEPAM

Common Name

English

2H-1,4-BENZODIAZEPIN-2-ONE

Systematic Name

English

2-CHLORODIAZEPAM [HSDB]

Common Name

English

2H-1,4-BENZODIAZEPIN-2-ONE, 7-CHLORO-5-(2-CHLOROPHENYL)-1,3-DIHYDRO-1-METHYL-

Systematic Name

English

Classification Tree Code System Code

WIKIPEDIA

Designer-drugs-Diclazepam