1-METHYLPYRROLIDINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C5H11N
Molecular Weight	85.1475
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1CCCC1

InChI

InChIKey=AVFZOVWCLRSYKC-UHFFFAOYSA-N

InChI=1S/C5H11N/c1-6-4-2-3-5-6/h2-5H2,1H3

HIDE SMILES / InChI

Molecular Formula	C5H11N
Molecular Weight	85.1475
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
O-Phosphonatomethylcholine, its analogues, alkyl esters, and their biological activity.	2001 Dec 6	11728191
Some aspects of NaBH(4) reduction in NMP.	2002 Aug	12057647
Studies on a soft glycopyrrolate analog, SG-1.	2002 Feb	11878191
A comparative analysis of glove permeation resistance to paint stripping formulations.	2002 Jan-Feb	11843429
Nicotine breaks down preformed Alzheimer's beta-amyloid fibrils in vitro.	2002 Nov 1	12399141
Acetylation of rice straw with or without catalysts and its characterization as a natural sorbent in oil spill cleanup.	2002 Oct 23	12381129
N-methylpiperidinemethyl, N-methylpyrrolidyl and N-methylpyrrolidinemethyl esters as PET radiotracers for acetylcholinesterase activity.	2003 Apr	12745021
Kinetics and mechanism of ring transformation of S-[1-(4-methoxyphenyl)pyrrolidin-2-on-3-yl]isothiuronium bromide to 2-methylimino-5-[2-(4-methoxyphenylamino)ethyl]thiazolidin-4-one.	2003 Apr 7	12926396
A new highly asymmetric chelation-controlled heck arylation.	2003 Mar 26	12643695
A simple and sensitive GC method for determination of N-methylpyrrolidine in cefepime and its preparation.	2003 Nov 24	14623607
Physicochemical determinants for drug induced blockade of HERG potassium channels: effect of charge and charge shielding.	2003 Oct	15326914
N-n-alkylpyridinium analogs, a novel class of nicotinic receptor antagonists: selective inhibition of nicotine-evoked [3H] dopamine overflow from superfused rat striatal slices.	2003 Sep	12766255
Nicotine-related alkaloids and metabolites as inhibitors of human cytochrome P-450 2A6.	2004 Feb 15	14757175
A new class of potent non-imidazole H(3) antagonists: 2-aminoethylbenzofurans.	2004 Feb 9	14741270
Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the antipsychotic drug sulpiride.	2004 Jan 19	14698154
Molecular dissection of tropisetron, an alpha7 nicotinic acetylcholine receptor-selective partial agonist.	2005 Apr 22	15781147
5-substituted, 6-substituted, and unsubstituted 3-heteroaromatic pyridine analogues of nicotine as selective inhibitors of cytochrome P-450 2A6.	2005 Jan 13	15634016
Synthesis of new, potent avermectin-like insecticidal agents.	2005 Jul 4	15922315
Direct synthesis of fused 1,2,3,4,5-pentathiepins.	2005 Oct 7	16172686
A nonradioactive high-throughput/high-content assay for measurement of the human serotonin reuptake transporter function in vitro.	2006 Dec	17099247
Glyoxalase I-type hemithioacetal isomerization reactivity of a mononuclear Ni(II) deprotonated amide complex.	2006 Dec 27	17177453
EPR studies of amine radical cations. Part 2. Thermal and photo-induced rearrangements of propargylamine and allylamine radical cations in low-temperature freon matrices.	2006 Dec 28	17181339
Modeling proline ligation in the heme-dependent CO sensor, CooA, using small-molecule analogs.	2006 Jul	16724227
Influence of endotoxin induced fever on the pharmacokinetics of intramuscularly administered cefepime in rabbits.	2006 Jun	16645340
Electrokinetic chromatographic characterization of novel pseudo-phases based on N-alkyl-N-methylpyrrolidinium ionic liquid type surfactants.	2006 Nov	17075943
Synthetic inhibitors of cytochrome P-450 2A6: inhibitory activity, difference spectra, mechanism of inhibition, and protein cocrystallization.	2006 Nov 30	17125252
The synthesis of N,O-ferrocenyl pyrrolidine-containing ligands and their application in the diethyl- and diphenylzinc addition to aromatic aldehydes.	2006 Sep 29	16995663
Nicotine: on the potential role of ionic liquids for its processing and purification.	2007 Jul 19	17595131
Anti-fibrillogenic and fibril-destabilizing activity of nicotine in vitro: implications for the prevention and therapeutics of Lewy body diseases.	2007 Jun	17425956
Abstracts of papers presented at the 2008 pittsburgh conference.	2008	19365566
Evaluation of traps and lures for mass trapping of Mediterranean fruit fly in citrus groves.	2008 Feb	18330126
1-Methyl-1-propyl-pyrrolidinium chloride.	2008 Feb 29	21201968
1,1'-Dimethyl-1,1'-(butane-1,4-di-yl)dipyrrolidinium dibromide methanol disolvate.	2008 Jan 11	21201444
Preparation of second generation ionic liquids by efficient solvent-free alkylation of N-heterocycles with chloroalkanes.	2008 Jan 25	18259137
Fiber diffraction as a screen for amyloid inhibitors.	2008 Jun	18537544
Protic ionic liquids based on the dimeric and oligomeric anions: [(AcO)xH(x-1)]-.	2008 May 28	18473045
Rapid homogeneous lauroylation of wheat straw hemicelluloses under mild conditions.	2008 Nov 24	18793765
An improved ion chromatographic method for fast and sensitive determination of N-methylpyrrolidine in cefepime hydrochloride.	2009 Aug	19772725
5-(2-Pyrrolidinyl)oxazolidinones and 2-(2-pyrrolidinyl)benzodioxanes: synthesis of all the stereoisomers and alpha4beta2 nicotinic affinity.	2009 Feb 1	19097783
Selective triplet-state formation during charge recombination in a fullerene/Bodipy molecular dyad (Bodipy=borondipyrromethene).	2009 Jul 27	19551782
Using the cationic surfactants N-cetyl-N-methylpyrrolidinium bromide and 1-cetyl-3-methylimidazolium bromide for sweeping-micellar electrokinetic chromatography.	2009 Jul 3	19464693
Embryotoxic potential of N-methyl-pyrrolidone (NMP) and three of its metabolites using the rat whole embryo culture system.	2009 Jun 1	19281833
Formation and properties of stabilized aluminum nanoparticles.	2009 Mar	20355993
Evaluation of Pharmasolve corneal permeability enhancement and its irritation on rabbit eyes.	2009 May	19514982
Pyrrolidinium ionic liquid crystals with pendant mesogenic groups.	2009 May 19	19374454
Prospective monitoring of cefepime in intensive care unit adult patients.	2010	20359352
A simple and rapid dispersive liquid-liquid microextraction method followed by GC-FID for determination of N-methylpyrrolidine in cefepime.	2010 Dec	20949500
Validation of capillary electrophoresis method for determination of N-methylpyrrolidine in cefepime for injection.	2010 Nov	21044414

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:47:24 GMT 2023` Edited by `admin` on `Fri Dec 15 17:47:24 GMT 2023`
Record UNII	06509TZU6C
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1-METHYLPYRROLIDINE

Systematic Name

English

CEFEPIME IMPURITY G [EP IMPURITY]

Common Name

English

PYRROLIDINE, 1-METHYL-

Systematic Name

English

N-METHYLTETRAHYDROPYRROLE

Systematic Name

English

NSC-65579

Code

English

N-METHYLPYRROLIDINE

Systematic Name

English

METHYLPYRROLIDINE, 1-

Systematic Name

English

NSC-65

Code

English

CEFEPIME DIHYDROCHLORIDE MONOHYDRATE IMPURITY G [EP IMPURITY]

Common Name

English

Code System Code Type Description

ECHA (EC/EINECS)

204-438-5