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Details

Stereochemistry ACHIRAL
Molecular Formula C5H11N
Molecular Weight 85.1475
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1-METHYLPYRROLIDINE

SMILES

CN1CCCC1

InChI

InChIKey=AVFZOVWCLRSYKC-UHFFFAOYSA-N
InChI=1S/C5H11N/c1-6-4-2-3-5-6/h2-5H2,1H3

HIDE SMILES / InChI

Molecular Formula C5H11N
Molecular Weight 85.1475
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
A simple and rapid dispersive liquid-liquid microextraction method followed by GC-FID for determination of N-methylpyrrolidine in cefepime.
2010-12
Validation of capillary electrophoresis method for determination of N-methylpyrrolidine in cefepime for injection.
2010-11
Prospective monitoring of cefepime in intensive care unit adult patients.
2010
An improved ion chromatographic method for fast and sensitive determination of N-methylpyrrolidine in cefepime hydrochloride.
2009-08
Selective triplet-state formation during charge recombination in a fullerene/Bodipy molecular dyad (Bodipy=borondipyrromethene).
2009-07-27
Using the cationic surfactants N-cetyl-N-methylpyrrolidinium bromide and 1-cetyl-3-methylimidazolium bromide for sweeping-micellar electrokinetic chromatography.
2009-07-03
Embryotoxic potential of N-methyl-pyrrolidone (NMP) and three of its metabolites using the rat whole embryo culture system.
2009-06-01
Pyrrolidinium ionic liquid crystals with pendant mesogenic groups.
2009-05-19
Evaluation of Pharmasolve corneal permeability enhancement and its irritation on rabbit eyes.
2009-05
Formation and properties of stabilized aluminum nanoparticles.
2009-03
5-(2-Pyrrolidinyl)oxazolidinones and 2-(2-pyrrolidinyl)benzodioxanes: synthesis of all the stereoisomers and alpha4beta2 nicotinic affinity.
2009-02-01
Rapid homogeneous lauroylation of wheat straw hemicelluloses under mild conditions.
2008-11-24
Fiber diffraction as a screen for amyloid inhibitors.
2008-06
Protic ionic liquids based on the dimeric and oligomeric anions: [(AcO)xH(x-1)]-.
2008-05-28
1-Methyl-1-propyl-pyrrolidinium chloride.
2008-02-29
Evaluation of traps and lures for mass trapping of Mediterranean fruit fly in citrus groves.
2008-02
Preparation of second generation ionic liquids by efficient solvent-free alkylation of N-heterocycles with chloroalkanes.
2008-01-25
1,1'-Dimethyl-1,1'-(butane-1,4-di-yl)dipyrrolidinium dibromide methanol disolvate.
2008-01-11
Abstracts of papers presented at the 2008 pittsburgh conference.
2008
Nicotine: on the potential role of ionic liquids for its processing and purification.
2007-07-19
Anti-fibrillogenic and fibril-destabilizing activity of nicotine in vitro: implications for the prevention and therapeutics of Lewy body diseases.
2007-06
EPR studies of amine radical cations. Part 2. Thermal and photo-induced rearrangements of propargylamine and allylamine radical cations in low-temperature freon matrices.
2006-12-28
Glyoxalase I-type hemithioacetal isomerization reactivity of a mononuclear Ni(II) deprotonated amide complex.
2006-12-27
A nonradioactive high-throughput/high-content assay for measurement of the human serotonin reuptake transporter function in vitro.
2006-12
Synthetic inhibitors of cytochrome P-450 2A6: inhibitory activity, difference spectra, mechanism of inhibition, and protein cocrystallization.
2006-11-30
Electrokinetic chromatographic characterization of novel pseudo-phases based on N-alkyl-N-methylpyrrolidinium ionic liquid type surfactants.
2006-11
The synthesis of N,O-ferrocenyl pyrrolidine-containing ligands and their application in the diethyl- and diphenylzinc addition to aromatic aldehydes.
2006-09-29
Modeling proline ligation in the heme-dependent CO sensor, CooA, using small-molecule analogs.
2006-07
Influence of endotoxin induced fever on the pharmacokinetics of intramuscularly administered cefepime in rabbits.
2006-06
Direct synthesis of fused 1,2,3,4,5-pentathiepins.
2005-10-07
Synthesis of new, potent avermectin-like insecticidal agents.
2005-07-04
Molecular dissection of tropisetron, an alpha7 nicotinic acetylcholine receptor-selective partial agonist.
2005-04-22
5-substituted, 6-substituted, and unsubstituted 3-heteroaromatic pyridine analogues of nicotine as selective inhibitors of cytochrome P-450 2A6.
2005-01-13
Nicotine-related alkaloids and metabolites as inhibitors of human cytochrome P-450 2A6.
2004-02-15
A new class of potent non-imidazole H(3) antagonists: 2-aminoethylbenzofurans.
2004-02-09
Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the antipsychotic drug sulpiride.
2004-01-19
A simple and sensitive GC method for determination of N-methylpyrrolidine in cefepime and its preparation.
2003-11-24
Physicochemical determinants for drug induced blockade of HERG potassium channels: effect of charge and charge shielding.
2003-10
N-n-alkylpyridinium analogs, a novel class of nicotinic receptor antagonists: selective inhibition of nicotine-evoked [3H] dopamine overflow from superfused rat striatal slices.
2003-09
Kinetics and mechanism of ring transformation of S-[1-(4-methoxyphenyl)pyrrolidin-2-on-3-yl]isothiuronium bromide to 2-methylimino-5-[2-(4-methoxyphenylamino)ethyl]thiazolidin-4-one.
2003-04-07
N-methylpiperidinemethyl, N-methylpyrrolidyl and N-methylpyrrolidinemethyl esters as PET radiotracers for acetylcholinesterase activity.
2003-04
A new highly asymmetric chelation-controlled heck arylation.
2003-03-26
Nicotine breaks down preformed Alzheimer's beta-amyloid fibrils in vitro.
2002-11-01
Acetylation of rice straw with or without catalysts and its characterization as a natural sorbent in oil spill cleanup.
2002-10-23
Some aspects of NaBH(4) reduction in NMP.
2002-08
A comparative analysis of glove permeation resistance to paint stripping formulations.
2002-02-15
Studies on a soft glycopyrrolate analog, SG-1.
2002-02
O-Phosphonatomethylcholine, its analogues, alkyl esters, and their biological activity.
2001-12-06
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:52:51 GMT 2025
Edited
by admin
on Mon Mar 31 18:52:51 GMT 2025
Record UNII
06509TZU6C
Record Status Validated (UNII)
Record Version
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Name Type Language
1-METHYLPYRROLIDINE
Systematic Name English
NSC-65
Preferred Name English
CEFEPIME IMPURITY G [EP IMPURITY]
Common Name English
PYRROLIDINE, 1-METHYL-
Systematic Name English
N-METHYLTETRAHYDROPYRROLE
Systematic Name English
NSC-65579
Code English
N-METHYLPYRROLIDINE
Systematic Name English
METHYLPYRROLIDINE, 1-
Systematic Name English
CEFEPIME DIHYDROCHLORIDE MONOHYDRATE IMPURITY G [EP IMPURITY]
Common Name English
Code System Code Type Description
ECHA (EC/EINECS)
204-438-5
Created by admin on Mon Mar 31 18:52:51 GMT 2025 , Edited by admin on Mon Mar 31 18:52:51 GMT 2025
PRIMARY
EPA CompTox
DTXSID8042210
Created by admin on Mon Mar 31 18:52:51 GMT 2025 , Edited by admin on Mon Mar 31 18:52:51 GMT 2025
PRIMARY
PUBCHEM
8454
Created by admin on Mon Mar 31 18:52:51 GMT 2025 , Edited by admin on Mon Mar 31 18:52:51 GMT 2025
PRIMARY
NSC
65
Created by admin on Mon Mar 31 18:52:51 GMT 2025 , Edited by admin on Mon Mar 31 18:52:51 GMT 2025
PRIMARY
CAS
120-94-5
Created by admin on Mon Mar 31 18:52:51 GMT 2025 , Edited by admin on Mon Mar 31 18:52:51 GMT 2025
PRIMARY
FDA UNII
06509TZU6C
Created by admin on Mon Mar 31 18:52:51 GMT 2025 , Edited by admin on Mon Mar 31 18:52:51 GMT 2025
PRIMARY
NSC
65579
Created by admin on Mon Mar 31 18:52:51 GMT 2025 , Edited by admin on Mon Mar 31 18:52:51 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> METABOLITE INACTIVE
Converted rapidly to NMP-N-oxide
MINOR
URINE
Related Record Type Details
PARENT -> IMPURITY