ISCALIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 09:51:36 UTC 2023` Edited by `admin` on `Sat Dec 16 09:51:36 UTC 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	0628T707D0
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ISCALIMAB

Official Name

English

CFZ533

Code

English

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5 (B-CELL SURFACE ANTIGEN CD40))HUMAN MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN (1-450) (HOMO SAPIENS VH (IGHV3-30*03 (94%) (IGHD)-IGHJ4*01) (8.8.13) (1-120)-HOMO

Systematic Name

English

CFZ-533

Code

English

Iscalimab [WHO-DD]

Common Name

English

NVP-CFZ533

Code

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN CD40 ANTIGEN),(HUMAN MONOCLONAL CLONE NVS240705 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL CLONE NVS240705 .KAPPA.-CHAIN, DIMER

Common Name

English

iscalimab [INN]

Common Name

English

ISCALIMAB [USAN]

Common Name

English

Code System Code Type Description

DRUG BANK

DB15260

Created by admin on Sat Dec 16 09:51:36 UTC 2023 , Edited by admin on Sat Dec 16 09:51:36 UTC 2023

PRIMARY

NCI_THESAURUS

C175096

Created by admin on Sat Dec 16 09:51:36 UTC 2023 , Edited by admin on Sat Dec 16 09:51:36 UTC 2023

PRIMARY

USAN

GH-46

Created by admin on Sat Dec 16 09:51:36 UTC 2023 , Edited by admin on Sat Dec 16 09:51:36 UTC 2023

PRIMARY

CAS

2031153-61-2

Created by admin on Sat Dec 16 09:51:36 UTC 2023 , Edited by admin on Sat Dec 16 09:51:36 UTC 2023

PRIMARY

INN

10707

Created by admin on Sat Dec 16 09:51:36 UTC 2023 , Edited by admin on Sat Dec 16 09:51:36 UTC 2023

PRIMARY

FDA UNII

0628T707D0

Created by admin on Sat Dec 16 09:51:36 UTC 2023 , Edited by admin on Sat Dec 16 09:51:36 UTC 2023

PRIMARY

From	To
1_22	1_96
1_147	1_203
1_264	1_324
1_370	1_428
1_223	3_219
1_229	2_229
1_232	2_232
2_22	2_96
2_147	2_203
2_264	2_324
2_370	2_428
2_223	4_219
3_23	3_93
3_139	3_199
4_23	4_93
4_139	4_199

Related Record Type Details


					CA9PO31PIJ

TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5

TARGET -> INHIBITOR

Related Record Type Details


					0628T707D0

ISCALIMAB

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL