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Approval Year

Unknown
139594
Substance Class Protein
Created
by admin
on Sat Dec 16 09:51:36 GMT 2023
Edited
by admin
on Sat Dec 16 09:51:36 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
0628T707D0
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ISCALIMAB
USAN   INN  
Official Name English
CFZ533
Code English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5 (B-CELL SURFACE ANTIGEN CD40))HUMAN MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN (1-450) (HOMO SAPIENS VH (IGHV3-30*03 (94%) (IGHD)-IGHJ4*01) (8.8.13) (1-120)-HOMO
Systematic Name English
CFZ-533
Code English
Iscalimab [WHO-DD]
Common Name English
NVP-CFZ533
Code English
IMMUNOGLOBULIN G1, ANTI-(HUMAN CD40 ANTIGEN),(HUMAN MONOCLONAL CLONE NVS240705 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL CLONE NVS240705 .KAPPA.-CHAIN, DIMER
Common Name English
iscalimab [INN]
Common Name English
ISCALIMAB [USAN]
Common Name English
Code System Code Type Description
DRUG BANK
DB15260
Created by admin on Sat Dec 16 09:51:36 GMT 2023 , Edited by admin on Sat Dec 16 09:51:36 GMT 2023
PRIMARY
NCI_THESAURUS
C175096
Created by admin on Sat Dec 16 09:51:36 GMT 2023 , Edited by admin on Sat Dec 16 09:51:36 GMT 2023
PRIMARY
USAN
GH-46
Created by admin on Sat Dec 16 09:51:36 GMT 2023 , Edited by admin on Sat Dec 16 09:51:36 GMT 2023
PRIMARY
CAS
2031153-61-2
Created by admin on Sat Dec 16 09:51:36 GMT 2023 , Edited by admin on Sat Dec 16 09:51:36 GMT 2023
PRIMARY
INN
10707
Created by admin on Sat Dec 16 09:51:36 GMT 2023 , Edited by admin on Sat Dec 16 09:51:36 GMT 2023
PRIMARY
FDA UNII
0628T707D0
Created by admin on Sat Dec 16 09:51:36 GMT 2023 , Edited by admin on Sat Dec 16 09:51:36 GMT 2023
PRIMARY
From To
1_22 1_96
1_147 1_203
1_264 1_324
1_370 1_428
1_223 3_219
1_229 2_229
1_232 2_232
2_22 2_96
2_147 2_203
2_264 2_324
2_370 2_428
2_223 4_219
3_23 3_93
3_139 3_199
4_23 4_93
4_139 4_199
Related Record Type Details
TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5
TARGET -> INHIBITOR
Related Record Type Details
ISCALIMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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