U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C9H12N2O2
Molecular Weight 180.2038
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TYROSINAMIDE, L-

SMILES

N[C@@H](CC1=CC=C(O)C=C1)C(N)=O

InChI

InChIKey=PQFMNVGMJJMLAE-QMMMGPOBSA-N
InChI=1S/C9H12N2O2/c10-8(9(11)13)5-6-1-3-7(12)4-2-6/h1-4,8,12H,5,10H2,(H2,11,13)/t8-/m0/s1

HIDE SMILES / InChI

Molecular Formula C9H12N2O2
Molecular Weight 180.2038
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
In vitro selection of DNA aptamers that bind L-tyrosinamide.
2001 Oct
Probing the binding specificity of C-type lectins in vivo.
2003
Antineoplastic agents. 487. Synthesis and biological evaluation of the antineoplastic agent 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene and derived amino acid amides.
2003 Feb 13
Immobilized DNA aptamers as target-specific chiral stationary phases for resolution of nucleoside and amino acid derivative enantiomers.
2004 Feb 15
Influence of alkyl group on amide nitrogen atom on fluorescence quenching of tyrosine amide and N-acetyltyrosine amide.
2004 Oct 1
Antineoplastic agents. 515. Synthesis of human cancer cell growth inhibitors derived from 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene.
2005 Aug
CE with electrochemical detection for investigation of label-free recognition of amino acid amides by guanine-rich DNA aptamers.
2007 Aug
Physiological variations of stem cell factor and stromal-derived factor-1 in murine models of liver injury and regeneration.
2008 Mar
Microcalorimetrics studies of the thermodynamics and binding mechanism between L-tyrosinamide and aptamer.
2008 May 29
Image-guided and passively tumour-targeted polymeric nanomedicines for radiochemotherapy.
2008 Sep 16
Synthesis, spectroscopic and structural elucidation of tyrosinamide hydrogensquarate monohydrate.
2009 Feb
Electropolymerized tyrosine-based thin films: selective cell binding via peptide recognition to novel electropolymerized biomimetic tyrosine RGDY films.
2009 Jan 1
Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers.
2009 Jul
Identification of tyrosine 806 as a molecular determinant of RET kinase sensitivity to ZD6474.
2009 Mar
Noncompetitive fluorescence polarization aptamer-based assay for small molecule detection.
2009 Sep 1
Design strategies of fluorescent biosensors based on biological macromolecular receptors.
2010
Glycan labeling strategies and their use in identification and quantification.
2010 Aug
Inhibition of Ser/Thr phosphatases induces capacitation-associated signaling in the presence of Src kinase inhibitors.
2010 Mar 12
Patents

Patents

Substance Class Chemical
Created
by admin
on Fri Dec 15 17:16:40 GMT 2023
Edited
by admin
on Fri Dec 15 17:16:40 GMT 2023
Record UNII
05LU01CS4T
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TYROSINAMIDE, L-
Common Name English
BENZENEPROPANAMIDE, .ALPHA.-AMINO-4-HYDROXY-, (.ALPHA.S)-
Systematic Name English
TYROSINAMIDE
Common Name English
TYRN
Common Name English
AMIDATED L-TYROSINE
Common Name English
L-TYROSINE AMIDE
Common Name English
(S)-2-AMINO-3-(4-HYDOXYPHENYL)PROPANAMIDE
Systematic Name English
TYROSINE AMIDE
Common Name English
L-TYROSINAMIDE
Common Name English
Code System Code Type Description
CAS
4985-46-0
Created by admin on Fri Dec 15 17:16:40 GMT 2023 , Edited by admin on Fri Dec 15 17:16:40 GMT 2023
PRIMARY
FDA UNII
05LU01CS4T
Created by admin on Fri Dec 15 17:16:40 GMT 2023 , Edited by admin on Fri Dec 15 17:16:40 GMT 2023
PRIMARY
PUBCHEM
151243
Created by admin on Fri Dec 15 17:16:40 GMT 2023 , Edited by admin on Fri Dec 15 17:16:40 GMT 2023
PRIMARY
CHEBI
21412
Created by admin on Fri Dec 15 17:16:40 GMT 2023 , Edited by admin on Fri Dec 15 17:16:40 GMT 2023
PRIMARY
DRUG BANK
DB03380
Created by admin on Fri Dec 15 17:16:40 GMT 2023 , Edited by admin on Fri Dec 15 17:16:40 GMT 2023
PRIMARY
EPA CompTox
DTXSID70198120
Created by admin on Fri Dec 15 17:16:40 GMT 2023 , Edited by admin on Fri Dec 15 17:16:40 GMT 2023
PRIMARY
Related Record Type Details
ENANTIOMER -> ENANTIOMER