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Details

Stereochemistry ACHIRAL
Molecular Formula C4H5N
Molecular Weight 67.0892
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of METHACRYLONITRILE

SMILES

CC(=C)C#N

InChI

InChIKey=GYCMBHHDWRMZGG-UHFFFAOYSA-N
InChI=1S/C4H5N/c1-4(2)3-5/h1H2,2H3

HIDE SMILES / InChI

Molecular Formula C4H5N
Molecular Weight 67.0892
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Effect of caffeine and alcohol on the toxicity and metabolism of methacrylonitrile in male Sprague-Dawley rats.
2011-04-08
Photocycloaddition of enynones (4-acylbut-1-en-3-ynes) to alkenes.
2010-02-19
Cloning and functional expression of a nitrile hydratase (NHase) from Rhodococcus equi TG328-2 in Escherichia coli, its purification and biochemical characterisation.
2010-02
Comparative investigations of genotoxic activity of five nitriles in the comet assay and the Ames test.
2009-09-30
Elementary reactions and their role in gas-phase prebiotic chemistry.
2009-05-19
Magneto-responsive organogels prepared through surface-initiated atom transfer radical polymerization on iron nanoparticles.
2009-01
Novel catalytic activity of nitrile hydratase from Rhodococcus sp. N771.
2008-08
Effect of methacrylonitrile on membrane bound enzymes of rat brain.
2008-05-15
Investigation of xenobiotics metabolism, genotoxicity, and carcinogenicity using Cyp2e1(-/-) mice.
2007-10
Half-sandwich rhodium (and iridium) complexes as enantioselective catalysts for the 1,3-dipolar cycloaddition of 3,4-dihydroisoquinoline N-oxide to methacrylonitrile.
2007
Enantioselective addition of secondary phosphines to methacrylonitrile: catalysis and mechanism.
2005-12-07
Comparative metabolism of methacrylonitrile and acrylonitrile to cyanide using cytochrome P4502E1 and microsomal epoxide hydrolase-null mice.
2005-06-01
Directed organic grafting on locally doped silicon substrates.
2005-01
Brain lipid peroxidation and antioxidant status after acute methacrylonitrile intoxication.
2005
Nickel(II)-catalyzed highly enantioselective hydrophosphination of methacrylonitrile.
2004-11-17
Effects of aliphatic nitriles in micromass cultures of rat embryo limb bud cells.
2004-06
Characterization of the toxicity, mutagenicity, and carcinogenicity of methacrylonitrile in F344 Rats and B6C3F1 mice.
2003-04
Crystal structure of methyl endo-8-cyano-exo-8-methyl-3-oxo-2-oxabicyclo[2.2.2]oct-5-ene-6-carboxylate.
2003-03
Effect of methacrylonitrile on cytochrome P-450 2E1 (CYP2E1) expression in male F344 rats.
2002-04-12
Toxicology and carcinogenesis studies of methacrylonitrile (CAS No. 126-98-7) in F344/N rats and B6C3F1 mice (gavage studies).
2001-11
Comparative xenobiotic metabolism between Tg.AC and p53+/- genetically altered mice and their respective wild types.
2001-05
Role of cytochrome P-450 2E1 in methacrylonitrile metabolism and disposition.
1999-05
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:12:27 GMT 2025
Edited
by admin
on Mon Mar 31 19:12:27 GMT 2025
Record UNII
04S4K38612
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
METHACRYLONITRILE
MI  
Systematic Name English
NSC-24145
Preferred Name English
.ALPHA.-METHYLACRYLONITRILE
Systematic Name English
METHYLACRYLONITRILE [HSDB]
Common Name English
ISOBUTENENITRILE
Systematic Name English
ISOPROPENE CYANIDE
Common Name English
2-METHYL-2-PROPENENITRILE
Systematic Name English
2-CYANO-1-PROPENE
Systematic Name English
ISOPROPENYLNITRILE
Common Name English
METHACRYLONITRILE [MI]
Common Name English
Code System Code Type Description
MERCK INDEX
m7284
Created by admin on Mon Mar 31 19:12:27 GMT 2025 , Edited by admin on Mon Mar 31 19:12:27 GMT 2025
PRIMARY Merck Index
FDA UNII
04S4K38612
Created by admin on Mon Mar 31 19:12:27 GMT 2025 , Edited by admin on Mon Mar 31 19:12:27 GMT 2025
PRIMARY
MESH
C008385
Created by admin on Mon Mar 31 19:12:27 GMT 2025 , Edited by admin on Mon Mar 31 19:12:27 GMT 2025
PRIMARY
PUBCHEM
31368
Created by admin on Mon Mar 31 19:12:27 GMT 2025 , Edited by admin on Mon Mar 31 19:12:27 GMT 2025
PRIMARY
HSDB
5613
Created by admin on Mon Mar 31 19:12:27 GMT 2025 , Edited by admin on Mon Mar 31 19:12:27 GMT 2025
PRIMARY
CAS
126-98-7
Created by admin on Mon Mar 31 19:12:27 GMT 2025 , Edited by admin on Mon Mar 31 19:12:27 GMT 2025
PRIMARY
EPA CompTox
DTXSID1024176
Created by admin on Mon Mar 31 19:12:27 GMT 2025 , Edited by admin on Mon Mar 31 19:12:27 GMT 2025
PRIMARY
NSC
24145
Created by admin on Mon Mar 31 19:12:27 GMT 2025 , Edited by admin on Mon Mar 31 19:12:27 GMT 2025
PRIMARY
WIKIPEDIA
METHACRYLONITRILE
Created by admin on Mon Mar 31 19:12:27 GMT 2025 , Edited by admin on Mon Mar 31 19:12:27 GMT 2025
PRIMARY
ECHA (EC/EINECS)
204-817-5
Created by admin on Mon Mar 31 19:12:27 GMT 2025 , Edited by admin on Mon Mar 31 19:12:27 GMT 2025
PRIMARY
SMS_ID
300000053478
Created by admin on Mon Mar 31 19:12:27 GMT 2025 , Edited by admin on Mon Mar 31 19:12:27 GMT 2025
PRIMARY