MIDAZOGREL

Details

Stereochemistry	RACEMIC
Molecular Formula	C18H24N2O
Molecular Weight	284.396
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCC(OCC1=CC=CC=C1)\C=C\N2C=CN=C2

InChI

InChIKey=YPIURPNVKACZQH-ACCUITESSA-N

InChI=1S/C18H24N2O/c1-2-3-5-10-18(11-13-20-14-12-19-16-20)21-15-17-8-6-4-7-9-17/h4,6-9,11-14,16,18H,2-3,5,10,15H2,1H3/b13-11+

HIDE SMILES / InChI

Molecular Formula	C18H24N2O
Molecular Weight	284.396
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	1
Optical Activity	( + / - )

Description
Sources: Elks J., The Dictionary of Drugs: Chemical Data: Chemical Data, Structures, retrieved from:https://books.google.ru/books?id=0vXTBwAAQBAJ&pg=PA824&lpg=PA824&dq=MIDAZOGREL&source=bl&ots=6JTnv5Xwps&sig=ACfU3U2745N-XJQmLvFtTheM7z1LGFD2aA&hl=ru&sa=X&ved=2ahUKEwjH2KCY6NXiAhVoxIsKHWnRAuI4ChDoATAAegQICRAB#v=onepage&q=MIDAZOGREL&f=false | https://www.ncbi.nlm.nih.gov/pubmed/3082339

Midazogrel (CBS-645) is a specific inhibitor of thromboxane synthetase. It inhibits the platelet enzyme in human and is potentially useful as an antithrombotic agent. Midazogrel could be of interest in the treatment of the various diseases in which the pathological role of thromboxane A2 is suspected. However, information about the further development of this drug is not available.

Approval Year

PubMed

Title	Date	PubMed
Inhibition of platelet thromboxane synthetase by 1-(3-benzyloxy-1[E]octenyl)imidazole.	1986	3082339

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:21:39 GMT 2023` Edited by `admin` on `Fri Dec 15 16:21:39 GMT 2023`
Record UNII	04HCK0SD2O
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MIDAZOGREL

Official Name

English

(±)-1-((E)-3-(BENZYLOXY)-1-OCTENYL)IMIDAZOLE

Systematic Name

English

midazogrel [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1327